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    • Proteasome Activator Enhances Survival of Huntington's Disease Neuronal Model Cells 

      Seo, Hyemyung; Sonntag, Kai-Christian; Kim, Woori; Cattaneo, Elena; Isacson, Ole Stefan (Public Library of Science, 2007)
      In patients with Huntington's disease (HD), the proteolytic activity of the ubiquitin proteasome system (UPS) is reduced in the brain and other tissues. The pathological hallmark of HD is the intraneuronal nuclear protein ...