Browsing by Author "Ascherio, Alberto"

Now showing items 1-8 of 8

    • Dietary and Genetic Risk Factors for Parkinson's Disease 

      Hughes, Katherine Carlson (2016-04-25)
      Parkinson’s disease (PD) is the second most common neurodegenerative disease. Motor symptoms typically do not manifest until significant neuronal loss has already occurred, highlighting the need for early detection and ...

    • Genome-Wide Association Study of Circulating Vitamin D Levels 

      Ahn, Jiyoung; Yu, Kai; Stolzenberg-Solomon, Rachael; McCullough, Marjorie L.; Gallicchio, Lisa; Jacobs, Eric J.; Helzlsouer, Kathy; Jacobs, Kevin B.; Li, Qizhai; Weinstein, Stephanie J.; Purdue, Mark; Virtamo, Jarmo; Horst, Ronald; Chanock, Stephen; Hayes, Richard B.; Kraft, Peter; Albanes, Demetrius; Simon, Kelly Claire; Ascherio, Alberto B.; Wheeler, William; Hunter, David J. (Oxford University Press, 2010)
      The primary circulating form of vitamin D, 25-hydroxy-vitamin D [25(OH)D], is associated with multiple medical outcomes, including rickets, osteoporosis, multiple sclerosis and cancer. In a genome-wide association study ...

    • Overview of the Microbiome Among Nurses study (Micro-N) as an example of prospective characterization of the microbiome within cohort studies 

      Song, Mingyang; Everett, Christine; Li, Chengchen; Wilkinson, Jeremy; Nguyen, Long; McIver, Lauren; Ivey, Kerry; Izard, Jacques; Palacios, Natalia; Eliassen, A.; Willett, Walter; Ascherio, Alberto; Sun, Qi; Tworoger, Shelley; Chang, Andrew; Garrett, Wendy; Huttenhower, Curtis; Rimm, Eric; Song, Mingyang (Springer Science and Business Media LLC, 2021-04-21)
      A lack of prospective studies has been a major barrier for assessing the role of the microbiome in human health and disease on a population-wide scale. To address this significant knowledge gap, we have launched a large-scale ...

    • Particulate matter and risk of parkinson disease in a large prospective study of women 

      Palacios, Natalia; Fitzgerald, Kathryn C; Hart, Jaime E; Weisskopf, Marc G; Schwarzschild, Michael A; Ascherio, Alberto; Laden, Francine (BioMed Central, 2014)
      Background: Exposure to air pollution has been implicated in a number of adverse health outcomes and the effect of particulate matter (PM) on the brain is beginning to be recognized. Yet, no prospective study has examined ...

    • Perinatal Air Pollutant Exposures and Autism Spectrum Disorder in the Children of Nurses’ Health Study II Participants 

      Roberts, Andrea L.; Lyall, Kristen; Hart, Jaime E.; Laden, Francine; Just, Allan C.; Bobb, Jennifer F.; Koenen, Karestan C.; Ascherio, Alberto; Weisskopf, Marc G. (National Institute of Environmental Health Sciences, 2013)
      Objective: Air pollution contains many toxicants known to affect neurological function and to have effects on the fetus in utero. Recent studies have reported associations between perinatal exposure to air pollutants and ...

    • A Prospective Analysis of Airborne Metal Exposures and Risk of Parkinson Disease in the Nurses’ Health Study Cohort 

      Palacios, Natalia; Fitzgerald, Kathryn; Roberts, Andrea L.; Hart, Jaime E.; Weisskopf, Marc G.; Schwarzschild, Michael A.; Ascherio, Alberto; Laden, Francine (NLM-Export, 2014)
      Background: Exposure to metals has been implicated in the pathogenesis of Parkinson disease (PD). Objectives: We sought to examine in a large prospective study of female nurses whether exposure to airborne metals was ...

    • Research on the Premotor Symptoms of Parkinson’s Disease: Clinical and Etiological Implications 

      Chen, Honglei; Burton, Edward A.; Ross, G. Webster; Huang, Xuemei; Savica, Rodolfo; Abbott, Robert D.; Ascherio, Alberto; Caviness, John N.; Gao, Xiang; Gray, Kimberly A.; Hong, Jau-Shyong; Kamel, Freya; Jennings, Danna; Kirshner, Annette; Lawler, Cindy; Liu, Rui; Miller, Gary W.; Nussbaum, Robert; Peddada, Shyamal D.; Rick, Amy Comstock; Ritz, Beate; Siderowf, Andrew D.; Tanner, Caroline M.; Tröster, Alexander I.; Zhang, Jing (National Institute of Environmental Health Sciences, 2013)
      Background: The etiology and natural history of Parkinson’s disease (PD) are not well understood. Some non-motor symptoms such as hyposmia, rapid eye movement sleep behavior disorder, and constipation may develop during ...

    • Vitamin D and Neurodegenerative Disease With Selected Topics Related to Correlated and Missing Outcome Data 

      Fitzgerald, Kathryn C. (2015-09-15)
      The following dissertation addresses of two themes: the role of vitamin D and neurodegenerative diseases and methodologic concepts related to correlated missing outcome data. In the first chapter, the relation between ...