Now showing items 1-17 of 17

    • ABO Blood Group and Risk of Coronary Heart Disease in Two Prospective Cohort Studies 

      He, Meian; Wolpin, Brian; Rexrode, Kathy; Manson, JoAnn E.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Hu, Frank B.; Qi, Lu (American Heart Association, 2012)
      Objective-Epidemiological data regarding the association between ABO blood groups and risk of coronary heart disease (CHD) have been inconsistent. We sought to investigate the associations between ABO blood group and CHD ...
    • Association Between a Genetic Variant Related to Glutamic Acid Metabolism and Coronary Heart Disease in Individuals with Type 2 Diabetes 

      Qi, Lu; Qi, Qibin; Prudente, Sabrina; Mendonca, Christine; Andreozzi, Francesco; di Pietro, Natalia; Sturma, Mariella; Novelli, Valeria; Mannino, Gaia Chiara; Formoso, Gloria; Gervino, Ernest V.; Hauser, Thomas H.; Muehlschlegel, Jochen D.; Niewczas, Monika A.; Krolewski, Andrzej S.; Biolo, Gianni; Pandolfi, Assunta; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Sesti, Giorgio; Trischitta, Vincenzo; Hu, Frank; Doria, Alessandro (American Medical Association, 2013)
      IMPORTANCE Diabetes is associated with an elevated risk of coronary heart disease (CHD). Previous studies have suggested that the genetic factors predisposing to excess cardiovascular risk may be different in diabetic and ...
    • Associations of Bowel Movement Frequency with Risk of Cardiovascular Disease and Mortality among US Women 

      Ma, Wenjie; Li, Yanping; Heianza, Yoriko; Staller, Kyle D.; Chan, Andrew T.; Rimm, Eric B.; Rexrode, Kathryn M.; Qi, Lu (Nature Publishing Group, 2016)
      Emerging evidence suggests a potential impact of gastrointestinal function on cardiometabolic risk. Abnormal bowel movements have been related to various cardiovascular risk factors such as dyslipidemia, hypertension, ...
    • Determinants and Consequences of Obesity 

      Hruby, Adela; Manson, JoAnn; Qi, Lu; Malik, Vasanti; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Sun, Qi; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Hu, Frank (American Public Health Association, 2016)
      Objectives. To review the contribution of the Nurses' Health Studies (NHS and NHS II) in addressing hypotheses regarding risk factors for and consequences of obesity.Methods. Narrative review of the publications of the NHS ...
    • Diet, Lifestyle, Biomarkers, Genetic Factors, and Risk of Cardiovascular Disease in the Nurses’ Health Studies 

      Yu, Edward; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Qi, Lu; Rexrode, Kathryn; Albert, Christine; Sun, Qi; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Hu, Frank; Manson, JoAnn (American Public Health Association, 2016)
      Objectives. To review the contributions of the Nurses' Health Studies (NHSs) to the understanding of cardiovascular disease etiology in women.Methods. We performed a narrative review of the publications of the NHS and NHS ...
    • Dietary phosphatidylcholine and risk of all-cause and cardiovascular-specific mortality among US women and men 

      Zheng, Yan; Li, Yanping; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Hu, Frank; Albert, Christine; Rexrode, Kathryn; Manson, JoAnn; Qi, Lu (Oxford University Press, 2016)
      Background: The trimethylamine-containing nutrient phosphatidylcholine is the major dietary source for the gut microbiota metabolite trimethylamine-N-oxide (TMAO), which has been related to cardiovascular diseases (CVDs) ...
    • Gallstones and risk of coronary heart disease: prospective analysis of 270,000 men and women from 3 US cohorts and meta-analysis 

      Zheng, Yan; Xu, Min; Li, Yanping; Hruby, Adela; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Hu, Frank; Wirth, Janine; Albert, Christine; Rexrode, Kathryn; Manson, JoAnn; Qi, Lu (American Heart Association, 2016)
      Objective Gallstone disease has been related to cardiovascular risk factors; however, whether presence of gallstones predicts coronary heart disease (CHD) is not well established.Approach and Results We followed up 269142 ...
    • Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes 

      Qi, Lu; Cornelis, Marilyn C.; Kraft, Peter; Jensen, Majken; Dam, Rob van; Sun, Qi; Girman, Cynthia J.; Laurie, Cathy C.; Mirel, Daniel B.; Hunter, David J.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Hu, Frank B. (Oxford University Press, 2010)
      Blood soluble E-selectin (sE-selectin) levels have been related to various conditions such as type 2 diabetes. We performed a genome-wide association study among women of European ancestry from the Nurses' Health Study, ...
    • Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels 

      Qi, Qibin; Menzaghi, Claudia; Smith, Shelly; Liang, Liming; Rekeneire, Nathalie de; Garcia, Melissa E.; Lohman, Kurt K.; Miljkovic, Iva; Strotmeyer, Elsa S.; Cummings, Steve R.; Kanaya, Alka M.; Tylavsky, Frances A.; Satterfield, Suzanne; Ding, Jingzhong; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Trischitta, Vincenzo; Hu, Frank B.; Liu, Yongmei; Qi, Lu (Oxford University Press, 2012)
      Resistin is a polypeptide hormone that was reported to be associated with insulin resistance, inflammation and risk of type 2 diabetes and cardiovascular disease. We conducted a genome-wide association (GWA) study on ...
    • Joint association between birth weight at term and later life adherence to a healthy lifestyle with risk of hypertension: a prospective cohort study 

      Li, Yanping; Ley, Sylvia H.; VanderWeele, Tyler J.; Curhan, Gary C.; Rich-Edwards, Janet W.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Forman, John P.; Hu, Frank B.; Qi, Lu (BMC, 2015)
      Background: Low birth weight and unhealthy lifestyles in adulthood have been independently associated with an elevated risk of hypertension. However, no study has examined the joint effects of these factors on incidence ...
    • Lifestyle Cardiovascular Risk Score, Genetic Risk Score, and Myocardial Infarction in Hispanic/Latino Adults Living in Costa Rica 

      Sotos‐Prieto, Mercedes; Baylin, Ana; Campos, Hannia; Qi, Lu; Mattei, Josiemer (John Wiley and Sons Inc., 2016)
      Background: A lifestyle cardiovascular risk score (LCRS) and a genetic risk score (GRS) have been independently associated with myocardial infarction (MI) in Hispanics/Latinos. Interaction or joint association between these ...
    • Novel locus including FGF21 is associated with dietary macronutrient intake 

      Chu, Audrey Y.; Workalemahu, Tsegaselassie; Paynter, Nina P.; Rose, Lynda M.; Giulianini, Franco; Tanaka, Toshiko; Ngwa, Julius S.; Qi, Qibin; Curhan, Gary C.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Hunter, David J.; Pasquale, Louis R.; Ridker, Paul M.; Hu, Frank B.; Chasman, Daniel I.; Qi, Lu (Oxford University Press, 2013)
      Dietary intake of macronutrients (carbohydrate, protein, and fat) has been associated with risk of chronic conditions such as obesity and diabetes. Family studies have reported a moderate contribution of genetics to variation ...
    • Phobic anxiety symptom scores and incidence of type 2 diabetes in US men and women 

      Farvid, Maryam; Qi, Lu; Hu, Frank; Kawachi, Ichiro; Okereke, Olivia; Kubzansky, Laura; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600 (, 2014)
      Context: Emotional stress may be a risk factor for type 2 diabetes (T2D), but the relation between phobic anxiety symptoms and risk of T2D is uncertain. Objective: To evaluate prospectively the association between phobic ...
    • Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children 

      Kilpeläinen, Tuomas O.; Qi, Lu; Brage, Soren; Sharp, Stephen J.; Sonestedt, Emily; Demerath, Ellen; Ahmad, Tariq; Mora, Samia; Kaakinen, Marika; Sandholt, Camilla Helene; Holzapfel, Christina; Autenrieth, Christine S.; Hyppönen, Elina; Cauchi, Stéphane; He, Meian; Kutalik, Zoltan; Kumari, Meena; Stančáková, Alena; Meidtner, Karina; Balkau, Beverley; Tan, Jonathan T.; Mangino, Massimo; Timpson, Nicholas J.; Song, Yiqing; Zillikens, M. Carola; Jablonski, Kathleen A.; Garcia, Melissa E.; Johansson, Stefan; Bragg-Gresham, Jennifer L.; Wu, Ying; van Vliet-Ostaptchouk, Jana V.; Onland-Moret, N. Charlotte; Zimmermann, Esther; Rivera, Natalia V.; Tanaka, Toshiko; Stringham, Heather M.; Silbernagel, Günther; Kanoni, Stavroula; Feitosa, Mary F.; Snitker, Soren; Ruiz, Jonatan R.; Metter, Jeffery; Larrad, Maria Teresa Martinez; Atalay, Mustafa; Hakanen, Maarit; Amin, Najaf; Cavalcanti-Proença, Christine; Grøntved, Anders; Hallmans, Göran; Jansson, John-Olov; Kuusisto, Johanna; Kähönen, Mika; Lutsey, Pamela L.; Nolan, John J.; Palla, Luigi; Pedersen, Oluf; Pérusse, Louis; Renström, Frida; Scott, Robert A.; Shungin, Dmitry; Sovio, Ulla; Tammelin, Tuija H.; Rönnemaa, Tapani; Lakka, Timo A.; Uusitupa, Matti; Rios, Manuel Serrano; Ferrucci, Luigi; Bouchard, Claude; Meirhaeghe, Aline; Fu, Mao; Walker, Mark; Borecki, Ingrid B.; Dedoussis, George V.; Fritsche, Andreas; Ohlsson, Claes; Boehnke, Michael; Bandinelli, Stefania; van Duijn, Cornelia M.; Ebrahim, Shah; Lawlor, Debbie A.; Gudnason, Vilmundur; Harris, Tamara B.; Sørensen, Thorkild I. A.; Mohlke, Karen L.; Hofman, Albert; Uitterlinden, André G.; Tuomilehto, Jaakko; Lehtimäki, Terho; Raitakari, Olli; Isomaa, Bo; Njølstad, Pål R.; Florez, Jose C.; Liu, Simin; Ness, Andy; Spector, Timothy D.; Tai, E. Shyong; Froguel, Philippe; Boeing, Heiner; Laakso, Markku; Marmot, Michael (Public Library of Science, 2011)
      Background: The FTO gene harbors the strongest known susceptibility locus for obesity. While many individual studies have suggested that physical activity (PA) may attenuate the effect of FTO on obesity risk, other studies ...
    • Sugar-Sweetened Beverages and Genetic Risk of Obesity 

      Qi, Qibin; Chu, Audrey Y.; Kang, Jae H.; Jensen, Majken K.; Curhan, Gary C.; Pasquale, Louis R.; Ridker, Paul M.; Hunter, David J.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Chasman, Daniel I.; Hu, Frank B.; Qi, Lu (Massachusetts Medical Society, 2012)
      BACKGROUND Temporal increases in the consumption of sugar-sweetened beverages have paralleled the rise in obesity prevalence, but whether the intake of such beverages interacts with the genetic predisposition to adiposity ...
    • Television Watching, Leisure-Time Physical Activity and the Genetic Predisposition in Relation to Body Mass Index in Women and Men 

      Qi, Qibin; Li, Yanping; Chomistek, Andrea K.; Kang, Jae H.; Curhan, Gary C.; Pasquale, Louis R.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Hu, Frank B.; Qi, Lu (American Heart Association, 2012)
      Background-Previous studies on gene-lifestyle interaction and obesity have focused mostly on the FTO gene and physical activity, whereas little attention has been paid to sedentary behavior as indicated by television (TV) ...
    • Whole grain, cereal fiber, bran, and germ intake and the risks of all-cause and CVD-specific mortality among women with type 2 diabetes 

      He, Meian; Dam, Rob van; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Hu, Frank B.; Qi, Lu (American Heart Association, 2010)