Now showing items 1-4 of 4

    • GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration 

      Tamura, Rodrigo E.; Paccez, Juliano D.; Duncan, Kristal C.; Morale, Mirian G.; Simabuco, Fernando M.; Dillon, Simon; Correa, Ricardo G.; Gu, Xuesong; Libermann, Towia A.; Zerbini, Luiz F. (Impact Journals LLC, 2016)
      The epithelium-specific Ets transcription factor, SPDEF, plays a critical role in metastasis of prostate and breast cancer cells. While enhanced SPDEF expression blocks migration and invasion, knockdown of SPDEF expression ...
    • Meta-analysis of transcriptome data identifies a novel 5-gene pancreatic adenocarcinoma classifier 

      Bhasin, Manoj K.; Ndebele, Kenneth; Bucur, Octavian; Yee, Eric U.; Otu, Hasan H.; Plati, Jessica; Bullock, Andrea; Gu, Xuesong; Castan, Eduardo; Zhang, Peng; Najarian, Robert; Muraru, Maria S.; Miksad, Rebecca; Khosravi-Far, Roya; Libermann, Towia A. (Impact Journals LLC, 2016)
      Purpose Pancreatic ductal adenocarcinoma (PDAC) is largely incurable due to late diagnosis. Superior early detection biomarkers are critical to improving PDAC survival and risk stratification. Experimental Design Optimized ...
    • Recurrent Olfactory Neuroblastoma Treated With Cetuximab and Sunitinib: A Case Report 

      Wang, Lizhi; Ding, Yan; Wei, Lai; Zhao, Dewei; Wang, Ruoyu; Zhang, Yuewei; Gu, Xuesong; Wang, Zhiqiang (Wolters Kluwer Health, 2016)
      Abstract Olfactory neuroblastoma (ONB) is a rare cancer originating in the olfactory epithelium of the nasal vault. The recurrence rate of ONB is high, as the standard treatment of surgery followed by radiotherapy and/or ...
    • Tie2 protects the vasculature against thrombus formation in systemic inflammation 

      Higgins, Sarah; De Ceunynck, Karen; Kellum, John; Chen, Xiuying; Gu, Xuesong; Chaudhry, Sharjeel; Schulman, Sol; Libermann, Towia; Lu, Shulin; Shapiro, Nathan; Christiani, David; Flaumenhaft, Robert; Parikh, & (American Society for Clinical Investigation, 2018-03-05)
      Disordered coagulation contributes to death in sepsis and lacks effective treatments. Existing markers of disseminated intravascular coagulation (DIC) reflect its sequelae rather than its causes, delaying diagnosis and ...