Now showing items 1-20 of 26

    • Correlative light and electron microscopy using cathodoluminescence from nanoparticles with distinguishable colours 

      Glenn, David R.; Zhang, Huidan; Kasthuri, Narayanan; Schalek, Richard L.; Lo, P. K.; Trifonov, Alexei; Park, Hongkun; Lichtman, Jeff; Walsworth, Ronald L. (Nature Publishing Group, 2012)
      Correlative light and electron microscopy promises to combine molecular specificity with nanoscale imaging resolution. However, there are substantial technical challenges including reliable co-registration of optical and ...
    • Coupled Spins in Diamond: From Quantum Control to Metrology and Many-Body Physics 

      Kucsko, Georg (2016-05-16)
      The study of quantum mechanics, together with the ability to coherently control and manipulate quantum systems in the lab has led to a myriad of discoveries and real world applications. In this thesis we present experiments ...
    • Coupling of NV Centers to Photonic Crystal Nanobeams in Diamond 

      Hausmann, Birgit Judith Maria; Shields, Brendan John; Quan, Qimin; Chu, Yiwen; de Leon, Nathalie Pulmones; Evans, Ruffin Eley; Burek, Michael John; Zibrov, Alexander S; Markham, M.; Twitchen, D. J.; Park, Hongkun; Lukin, Mikhail D.; Loncar, Marko (American Chemical Society (ACS), 2013)
      The realization of efficient optical interfaces for solid-state atom-like systems is an important problem in quantum science with potential applications in quantum communications and quantum information processing. We ...
    • Deterministic Coupling of a Single Nitrogen Vacancy Center to a Photonic Crystal Cavity 

      Englund, Dirk; Shields, Brendan John; Rivoire, Kelley; Hatami, Fariba; Vučković, Jelena; Park, Hongkun; Lukin, Mikhail D. (American Chemical Society, 2010)
      We describe and experimentally demonstrate a technique for deterministic, large coupling between a photonic crystal (PC) nanocavity and single photon emitters. The technique is based on in situ scanning of a PC cavity over ...
    • Dynamic regulatory network controlling Th17 cell differentiation 

      Yosef, Nir; Shalek, Alex K.; Gaublomme, Jellert T.; Jin, Hulin; Lee, Youjin; Awasthi, Amit; Wu, Chuan; Karwacz, Katarzyna; Xiao, Sheng; Jorgolli, Marsela; Gennert, David; Satija, Rahul; Shakya, Arvind; Lu, Diana Y.; Trombetta, John J.; Pillai, Meenu R.; Ratcliffe, Peter J.; Coleman, Mathew L.; Bix, Mark; Tantin, Dean; Park, Hongkun; Kuchroo, Vijay K.; Regev, Aviv (2013)
      Despite their importance, the molecular circuits that control the differentiation of naïve T cells remain largely unknown. Recent studies that reconstructed regulatory networks in mammalian cells have focused on short-term ...
    • Elucidation of immune cell function via nanotechnology and single-cell profiling. 

      Gaublomme, Jellert Thomas (2014-06-06)
      A healthy immune system's core challenge is to mount appropriate responses to an immense and unknown variety of antigenic stimuli. By unraveling the regulatory networks that drive and control immune-cell behaviors, we can ...
    • Free-Standing Mechanical and Photonic Nanostructures in Single-Crystal Diamond 

      Burek, Michael John; de Leon, Nathalie Pulmones; Shields, Brendan John; Hausmann, Birgit Judith Maria; Chu, Yiwen; Quan, Qimin; Zibrov, Alexander S; Park, Hongkun; Lukin, Mikhail D.; Loncar, Marko (American Chemical Society (ACS), 2012)
      A variety of nanoscale photonic, mechanical, electronic, and optoelectronic devices require scalable thin film fabrication. Typically, the device layer is defined by thin film deposition on a substrate of a different ...
    • Integrated Nanoscale Tools for Interrogating Living Cells 

      Jorgolli, Marsela (2015-05-13)
      The development of next-generation, nanoscale technologies that interface biological systems will pave the way towards new understanding of such complex systems. Nanowires – one-dimensional nanoscale structures – have shown ...
    • Magnetic Field Imaging with Nitrogen-Vacancy Ensembles 

      Pham, Linh My; Le Sage, David Anthony; Stanwix, Paul L.; Yeung, Tsun Kwan; Glenn, David R.; Trifonov, Alexei; Cappellaro, Paola; Hemmer, Philip; Lukin, Mikhail D.; Park, Hongkun; Yacoby, Amir; Walsworth, Ronald L. (Institute of Physics, 2011)
      We demonstrate a method of imaging spatially varying magnetic fields using a thin layer of nitrogen-vacancy (NV) centers at the surface of a diamond chip. Fluorescence emitted by the two-dimensional NV ensemble is detected ...
    • Magnetic Resonance Detection of Individual Proton Spins Using Quantum Reporters 

      Sushkov, Alexander; Lovchinsky, I.; Chisholm, N.; Walsworth, Ronald Lee; Park, Hongkun; Lukin, Mikhail D. (American Physical Society (APS), 2014)
      We demonstrate a method of magnetic resonance imaging with single nuclear-spin sensitivity under ambient conditions. Our method employs isolated electronic-spin quantum bits (qubits) as magnetic resonance “reporters” on ...
    • Magnetic resonance spectroscopy of an atomically thin material using a single-spin qubit 

      Lovchinsky, Igor; Lukin, Mikhail D.; Sanchez-Yamagishi, Javier; Urbach, Elana Kahn; Choi, Soonwon; Fang, Shiang; Andersen, Trond Ikdahl; Watanabe, Kenji; Taniguchi, Takashi; Bylinskii, Alexei; Kaxiras, Efthimios; Kim, Philip; Park, Hongkun (American Association for the Advancement of Science (AAAS), 2017)
      Two-dimensional (2D) materials offer a promising platform for exploring condensed matter phenomena and developing technological applications. However, the reduction of material dimensions to the atomic scale poses a challenge ...
    • Nanometre-scale thermometry in a living cell 

      Kucsko, Georg; Maurer, Peter; Yao, Norman Ying; KUBO, MICHAEL; Noh, Hyungi; Lo, P. K.; Park, Hongkun; Lukin, Mikhail D. (Nature Publishing Group, 2013)
      Sensitive probing of temperature variations on nanometre scales is an outstanding challenge in many areas of modern science and technology. In particular, a thermometer capable of subdegree temperature resolution over a ...
    • Nanoscale NMR spectroscopy and imaging of multiple nuclear species 

      DeVience, Stephen J.; Pham, Linh My; Lovchinsky, Igor; Sushkov, Alexander; Bar-Gill, Nir; Belthangady, Chinmay N.; Casola, Francesco; Corbett, Madeleine; Zhang, Huiliang; Lukin, Mikhail D.; Park, Hongkun; Yacoby, Amir; Walsworth, Ronald Lee (Nature Publishing Group, 2015)
      Nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI) provide non-invasive information about multiple nuclear species in bulk matter, with wide-ranging applications from basic physics and ...
    • Nanotools for Neuroscience and Brain Activity Mapping 

      Alivisatos, A. Paul; Andrews, Anne M.; Boyden, Edward S.; Chun, Miyoung; Church, George McDonald; Deisseroth, Karl; Donoghue, John P.; Fraser, Scott E.; Lippincott-Schwartz, Jennifer; Looger, Loren L.; Masmanidis, Sotiris; McEuen, Paul L.; Nurmikko, Arto V.; Park, Hongkun; Peterka, Darcy S.; Reid, Clay; Roukes, Michael L.; Scherer, Axel; Schnitzer, Mark; Sejnowski, Terrence J.; Shepard, Kenneth L.; Tsao, Doris; Turrigiano, Gina; Weiss, Paul; Xu, Chris; Yuste, Rafael; Zhuang, Xiaowei (American Chemical Society (ACS), 2013)
      Neuroscience is at a crossroads. Great effort is being invested into deciphering specific neural interactions and circuits. At the same time, there exist few general theories or principles that explain brain function. We ...
    • Nanowire electrodes for high-density stimulation and measurement of neural circuits 

      Robinson, Jacob T.; Jorgolli, Marsela; Park, Hongkun (Frontiers Media S.A., 2013)
      Brain-machine interfaces (BMIs) that can precisely monitor and control neural activity will likely require new hardware with improved resolution and specificity. New nanofabricated electrodes with feature sizes and densities ...
    • Nanowire-Mediated Delivery Enables Functional Interrogation of Primary Immune Cells: Application to the Analysis of Chronic Lymphocytic Leukemia 

      Shalek, Alexander Kann; Gaublomme, Jellert Thomas; Wang, Lili; Yosef, Nir; Chevrier, Nicolas; Andersen, Mette S.; Robinson, Jacob T.; Pochet, Nathalie; Neuberg, Donna S.; Gertner, Rona S.; Amit, Ido; Brown, Jennifer Ruth; Hacohen, Nir; Regev, Aviv; Wu, Cathy Ju-Ying; Park, Hongkun (American ChemicalSociety, 2012)
      A circuit level understanding of immune cells and hematological cancers has been severely impeded by a lack of techniques that enable intracellular perturbation without significantly altering cell viability and function. ...
    • Nanowires as Optoelectronic and Photonic Elements 

      Yu, Chun Liang (2013-02-08)
      Integrated photonic circuits require small photonic elements. Recent progress in nanowire synthesis and nanofabrication enables us to investigate the potential of nanowires in novel integrated photonic devices. This thesis ...
    • Near-field Electrical Detection of Optical Plasmons and Single Plasmon Sources 

      Falk, Abraham; Koppens, Frank; Yu, Chun Liang; Kang, Kibum; Snapp, Nathalie; Akimov, Alexey; Jo, Moon-Ho; Lukin, Mikhail D.; Park, Hongkun (Nature Publishing Group, 2009)
      Photonic circuits can be much faster than their electronic counterparts, but they are difficult to miniaturize below the optical wavelength scale. Nanoscale photonic circuits based on surface plasmon polaritons (SPPs) are ...
    • NMR technique for determining the depth of shallow nitrogen-vacancy centers in diamond 

      Pham, Linh My; DeVience, Stephen J.; Casola, Francesco; Lovchinsky, Igor; Sushkov, Alexander; Bersin, Eric Alexander; Lee, Junghyun; Urbach, Elana; Cappellaro, Paola; Park, Hongkun; Yacoby, Amir; Lukin, Mikhail D.; Walsworth, Ronald Lee (American Physical Society (APS), 2016)
      We demonstrate a robust experimental method for determining the depth of individual shallow nitrogen-vacancy (NV) centers in diamond with ∼1 nm uncertainty. We use a confocal microscope to observe single NV centers ...
    • Nuclear magnetic resonance detection and spectroscopy of single proteins using quantum logic 

      Lovchinsky, Igor; Sushkov, Alexander; Urbach, Elana Kahn; de Leon, N; Choi, Soonwon; De Greve, Kristiaan; Evans, Ruffin Eley; Gertner, Rona S.; Bersin, Eric Alexander; Muller, C; McGuinness, L.; Jelezko, F.; Walsworth, Ronald Lee; Park, Hongkun; Lukin, Mikhail D. (American Association for the Advancement of Science (AAAS), 2016)
      Nuclear magnetic resonance spectroscopy is a powerful tool for the structural analysis of organic compounds and biomolecules but typically requires macroscopic sample quantities. We use a sensor, which consists of two ...