Browsing by Author "Bertagnolli, Monica"

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    • Celecoxib inhibits early cutaneous wound healing 

      Fairweather, Mark; Heit, Yvonne I.; Buie, Justin David; Rosenberg, Laura Michele; Briggs, Alexandra; Orgill, Dennis Paul; Bertagnolli, Monica Marie (Elsevier BV, 2015)
      BACKGROUND: Cyclooxygenase-2 (COX-2) is an inducible enzyme that is rapidly upregulated in response to injury, resulting in the production of prostaglandin E2 (PGE2), a primary mediator of inflammation and wound healing. ...

    • Germline variants and advanced colorectal adenomas: Adenoma Prevention with Celecoxib trial genome-wide association study 

      Wang, Jiping; Carvajal-Carmona, Luis G.; Chu, Jen-Hwa; Zauber, Ann G.; KUBO, Michikai; Matsuda, Koichi; Dunlop, Malcolm; Houlston, Richard S.; Sieber, Oliver; Lipton, Lara; Gibbs, Peter; Martin, Nicholas G.; Montgomery, George Glennon; Young, Joanne; Baird, Paul N.; Ratain, Mark J.; Nakamura, Yusuke; Weiss, Scott Tillman; Tomlinson, Ian; Bertagnolli, Monica Marie (American Association for Cancer Research (AACR), 2013)
      Purpose: Identification of single nucleotide polymorphisms (SNPs) associated with development of advanced colorectal adenomas. Experimental Design: Discovery Phase: 1,406 Caucasian patients (139 advanced adenoma cases ...