Browsing by Author "Gold, Diane"

Now showing items 1-20 of 36

    • Air Pollution and ST-Segment Depression in Elderly Subjects 

      MacCallum, Gail; Canner, Marina J.; Gold, Diane R.; Litonjua, Augusto Ampil; Zanobetti, Antonella; Coull, Brent Andrew; Schwartz, Joel David; Verrier, Richard Leonard; Nearing, Bruce David; Suh MacIntosh, Helen H.; Stone, Peter Howard (National Institue of Environmental Health Sciences, 2005)
      Increased levels of daily ambient particle pollution have been associated with increased risk of cardiovascular morbidity. Black carbon (BC) is a measure of the traffic-related component of particles. We investigated ...

    • Air Pollution Exposure and Abnormal Glucose Tolerance during Pregnancy: The Project Viva Cohort 

      Fleisch, Abby F.; Gold, Diane R.; Rifas-Shiman, Sheryl L.; Koutrakis, Petros; Schwartz, Joel D.; Kloog, Itai; Melly, Steven; Coull, Brent A.; Zanobetti, Antonella; Gillman, Matthew W.; Oken, Emily (National Institute of Environmental Health Sciences, 2014)
      Background: Exposure to fine particulate matter (PM with diameter ≤ 2.5 μm; PM2.5) has been linked to type 2 diabetes mellitus, but associations with hyperglycemia in pregnancy have not been well studied. Methods: We studied ...

    • Air pollution exposure and gestational diabetes mellitus among pregnant women in Massachusetts: a cohort study 

      Fleisch, Abby F.; Kloog, Itai; Luttmann-Gibson, Heike; Gold, Diane R.; Oken, Emily; Schwartz, Joel D. (BioMed Central, 2016)
      Background: Rodent and human studies suggest an association between air pollution exposure and type 2 diabetes mellitus, but the extent to which air pollution is associated with gestational diabetes mellitus (GDM) is less ...

    • Ambient air pollution, lung function, and airway responsiveness in asthmatic children 

      Ierodiakonou, Despo; Zanobetti, Antonella; Coull, Brent Andrew; Melly, Steven John; Postma, Dirkje S.; Boezen, H. Marike; Vonk, Judith M.; Williams, Paul V.; Shapiro, Gail G.; McKone, Edward F.; Hallstrand, Teal S.; Koenig, Jane Q.; Schildcrout, Jonathan S.; Lumley, Thomas; Fuhlbrigge, Anne Louise; Koutrakis, Petros; Schwartz, Joel David; Weiss, Scott Tillman; Gold, Diane R. (Elsevier BV, 2016)
      Background: Although ambient air pollution has been linked to reduced lung function in healthy children, longitudinal analyses of pollution effects in asthma are lacking. Objective: To investigate pollution effects in ...

    • Ambient and Microenvironmental Particles and Exhaled Nitric Oxide Before and After a Group Bus Trip 

      Adar, Sara Dubowsky; Adamkiewicz, Gary; Gold, Diane R.; Schwartz, Joel David; Coull, Brent Andrew; Suh MacIntosh, Helen H. (National Institute of Environmental Health Sciences, 2007)
      Objectives: Airborne particles have been linked to pulmonary oxidative stress and inflammation. Because these effects may be particularly great for traffic-related particles, we examined associations between particle ...

    • Autonomic Effects of Controlled Fine Particulate Exposure in Young Healthy Adults: Effect Modification by Ozone 

      Fakhri, Asghar A.; Ilic, Ljubomir M.; Wellenius, Gregory A.; Urch, Bruce; Silverman, Frances; Gold, Diane R.; Mittleman, Murray A. (National Institute of Environmental Health Sciences, 2009)
      Background: Human controlled-exposure studies have assessed the impact of ambient fine particulate matter on cardiac autonomic function measured by heart rate variability (HRV), but whether these effects are modified by ...

    • Baseline Repeated Measures from Controlled Human Exposure Studies: Associations between Ambient Air Pollution Exposure and the Systemic Inflammatory Biomarkers IL-6 and Fibrinogen 

      Thompson, Aaron M.S.; Zanobetti, Antonella; Silverman, Frances; Schwartz, Joel David; Coull, Brent Andrew; Urch, Bruce; Speck, Mary; Brook, Jeffrey R.; Manno, Michael; Gold, Diane R. (National Institute of Environmental Health Sciences, 2009)
      Introduction: Systemic inflammation may be one of the mechanisms mediating the association between ambient air pollution and cardiovascular morbidity and mortality. Interleukin-6 (IL-6) and fibrinogen are biomarkers of ...

    • Birth cohorts in asthma and allergic diseases: Report of a NIAID/NHLBI/MeDALL joint workshop 

      Bousquet, Jean; Gern, James E.; Martinez, Fernando D.; Anto, Josep M.; Johnson, Christine Haynes; Holt, Patrick G.; Lemanske, Robert F.; Le Souëf, Peter N.; Tepper, Robert Ira; von Mutius, Erika R.M.; Arshad, S. Hasan; Bacharier, Leonard B.; Becker, Allan; Belanger, Kathleen; Bergström, Anna; Bernstein, David I.; Cabana, Michael D.; Carroll, Kecia N.; Castro, Mario; Cooper, Philip J.; Gillman, Matthew William; Gold, Diane R.; Henderson, John; Heinrich, Joachim; Hong, Soo-Jong; Jackson, Danielle; Keil, Thomas; Kozyrskyj, Anita L.; Lødrup Carlsen, Karin C.; Miller, Rachel Blair; Momas, Isabelle; Morgan, Wayne J.; Noel, Patricia; Ownby, Dennis R.; Pinart, Mariona; Ryan, Patrick H.; Schwaninger, Julie M.; Sears, Malcolm R.; Simpson, Angela; Smit, Henriette A.; Stern, Debra A.; Subbarao, Padmaja; Valenta, Rudolf; Wang, Xiaobin; Weiss, Scott Tillman; Wood, Robert J.; Wright, Anne L.; Wright, Rosalind Jo; Togias, Alkis; Gergen, Peter J. (Elsevier BV, 2014)
      Population-based birth cohorts on asthma and allergies increasingly provide new insights into the development and natural history of the diseases. Over 130 birth cohorts focusing on asthma and allergy have been initiated ...

    • Brachial Artery Responses to Ambient Pollution, Temperature, and Humidity in People with Type 2 Diabetes: A Repeated-Measures Study 

      Zanobetti, Antonella; Luttmann-Gibson, Heike; Horton, Edward S.; Cohen, Allison; Coull, Brent A.; Hoffmann, Barbara; Schwartz, Joel D.; Mittleman, Murray A.; Li, Yongsheng; Stone, Peter H.; de Souza, Celine; Lamparello, Brooke; Koutrakis, Petros; Gold, Diane R. (National Institute of Environmental Health Sciences, 2014)
      Background: Extreme weather and air pollution are associated with increased cardiovascular risk in people with diabetes. Objectives: In a population with diabetes, we conducted a novel assessment of vascular brachial artery ...

    • Controlled Exposure Study of Air Pollution and T-Wave Alternans in Volunteers without Cardiovascular Disease 

      Kusha, Marjan; Masse, Stephane; Farid, Talha; Urch, Bruce; Silverman, Frances; Brook, Robert D; Mangat, Iqwal; Speck, Mary; Nair, Krishnakumar; Poku, Kwaku; Wellenius, Gregory A; Nanthakumar, Kumaraswamy; Gold, Diane R.; Chris, Meyer; Mittleman, Murray A. (National Institute of Environmental Health Sciences, 2012)
      Background: Epidemiological studies have assessed T-wave alternans (TWA) as a possible mechanism of cardiac arrhythmias related to air pollution in high-risk subjects and have reported associations with increased TWA ...

    • Diabetes, Obesity, and Hypertension May Enhance Associations between Air Pollution and Markers of Systemic Inflammation 

      Dubowsky, Sara D.; Suh, Helen; Schwartz, Joel David; Coull, Brent Andrew; Gold, Diane R. (National Institute of Environmental Health Sciences, 2006)
      Airborne particulate matter (PM) may lead to increased cardiac risk through an inflammatory pathway. Therefore, we investigated associations between ambient PM and markers of systemic inflammation among repeated measures ...

    • Diagnostic accuracy of the bronchodilator response in children 

      Tse, Szewah; Gold, Diane R.; Sordillo, Joanne; Hoffman, Elaine; Gillman, Matthew William; Rifas-Shiman, Sheryl Lynn; Fuhlbrigge, Anne Louise; Tantisira, Kelan; Weiss, Scott Tillman; Litonjua, Augusto Ampil (Elsevier BV, 2013)
      Background: The bronchodilator response (BDR) reflects the reversibility of airflow obstruction and is recommended as an adjunctive test to diagnose asthma. The validity of the commonly used definition of BDR, a 12% or ...

    • Differences in Heart Rate Variability Associated with Long-Term Exposure to NO2 

      Dietrich, Denise Felber; Gemperli, Armin; Gaspoz, Jean-Michel; Schindler, Christian; Rochat, Thierry; Barthélémy, Jean-Claude; Pons, Marco; Roche, Frédéric; Probst Hensch, Nicole M.; Bridevaux, Pierre-Olivier; Gerbase, Margaret W.; Neu, Urs; Ackermann-Liebrich, Ursula; Liu, L.-J. Sally; Gold, Diane R.; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2008)
      Background: Heart rate variability (HRV), a measure of cardiac autonomic tone, has been associated with cardiovascular morbidity and mortality. Short-term studies have shown that subjects exposed to higher traffic-associated ...

    • Diversity of the Gut Microbiota and Eczema in Early Life 

      Forno, Erick; Onderdonk, Andrew Bruce; McCracken, John Patrick; Litonjua, Augusto Ampil; Laskey, Daniel; Delaney, Mary Louise Rodriguez; DuBois, Andrea M; Gold, Diane R.; Ryan, Louise Marie; Weiss, Scott Tillman; Celedón, Juan C (BioMed Central, 2008)
      Background: A modest number of prospective studies of the composition of the intestinal microbiota and eczema in early life have yielded conflicting results. Objective: To examine the relationship between the bacterial ...

    • DNA Hypomethylation, Ambient Particulate Matter, and Increased Blood Pressure: Findings From Controlled Human Exposure Experiments 

      Bellavia, Andrea; Urch, Bruce; Speck, Mary; Brook, Robert D.; Scott, Jeremy A.; Albetti, Benedetta; Behbod, Behrooz; North, Michelle; Valeri, Linda; Bertazzi, Pier Alberto; Silverman, Frances; Gold, Diane; A. Baccarelli, Andrea (Blackwell Publishing Ltd, 2013)
      Background: Short‐term exposures to fine (<2.5 μm aerodynamic diameter) ambient particulate‐matter (PM) have been related with increased blood pressure (BP) in controlled‐human exposure and community‐based studies. However, ...

    • Effects of Ambient Coarse, Fine, and Ultrafine Particles and Their Biological Constituents on Systemic Biomarkers: A Controlled Human Exposure Study 

      Liu, Ling; Urch, Bruce; Poon, Raymond; Szyszkowicz, Mieczyslaw; Speck, Mary; Gold, Diane R.; Wheeler, Amanda J.; Scott, James A.; Brook, Jeffrey R.; Thorne, Peter S.; Silverman, Frances S. (NLM-Export, 2015)
      Background: Ambient coarse, fine, and ultrafine particles have been associated with mortality and morbidity. Few studies have compared how various particle size fractions affect systemic biomarkers. Objectives: We examined ...

    • Effects of Endotoxin Exposure on Childhood Asthma Risk are Modified by a Genetic Polymorphism in ACAA1 

      Sordillo, Joanne; Sharma, Sunita; Poon, Audrey; Su, Jessica Ann Lasky; Belanger, Kathleen; Milton, Donald Kirby; Bracken, Michael B; Triche, Elizabeth W; Leaderer, Brian P; Gold, Diane R.; Litonjua, Augusto Ampil (BioMed Central, 2011)
      Background: Polymorphisms in the endotoxin-mediated TLR4 pathway genes have been associated with asthma and atopy. We aimed to examine how genetic polymorphisms in innate immunity pathways interact with endotoxin to influence ...

    • Environmental tobacco smoke, indoor allergens, and childhood asthma. 

      Gold, Diane R. (2000)
      Both environmental tobacco smoke and indoor allergens can exacerbate already established childhood albeit primarily through quite disparate mechanisms. In infancy and childhood, environmental tobacco smoke (ETS) exposure ...

    • Factors Affecting the Association between Ambient Concentrations and Personal Exposures to Particles and Gases 

      Sarnat, Stefanie Ebelt; Coull, Brent Andrew; Schwartz, Joel David; Gold, Diane R.; Suh MacIntosh, Helen H. (National Institute of Environmental Health Sciences, 2005)
      Results from air pollution exposure assessment studies suggest that ambient fine particles [particulate matter with aerodynamic diameter ≤ 2.5 μg (PM2.5)], but not ambient gases, are strong proxies of corresponding personal ...

    • Fungal Levels in the Home and Allergic Rhinitis by 5 Years of Age 

      Stark, Paul C.; Celedón, Juan C.; Chew, Ginger L.; Ryan, Louise Marie; Burge, Harriet A.; Muilenberg, Michael L.; Gold, Diane R. (National Institute of Environmental Health Sciences, 2005)
      Studies have repeatedly demonstrated that sensitization to fungi, such as Alternaria, is strongly associated with allergic rhinitis and asthma in children. However, the role of exposure to fungi in the development of ...