Browsing by Author "Sassi, Slim"

Now showing items 1-1 of 1

    • Small-Molecule Targeting of Brachyury Transcription Factor Addiction in Chordoma 

      Sharifnia, Tanaz; Wawer, Mathias J.; Chen, Ting; Huang, Qing-Yuan; Weir, Barbara A.; Sizemore, Ann; Lawlor, Matthew A.; Goodale, Amy; Cowley, Glenn S.; Vazquez, Francisca; Ott, Christopher; Francis, Joshua M.; Sassi, Slim; Cogswell, Patricia; Sheppard, Hadley E.; Zhang, Tinghu; Gray, Nathanael; Clarke, Paul A.; Blagg, Julian; Workman, Paul; Sommer, Josh; Hornicek, Francis; Root, David E.; Hahn, William; Bradner, James E.; Wong, Kwok-Kin; Clemons, Paul A.; Lin, Charles Y.; Kotz, Joanne D.; Schreiber, Stuart (Springer Science and Business Media LLC, 2019-01-21)
      Chordoma is a primary bone cancer with no approved therapy. The identification of therapeutic targets in this disease has been challenging due to the infrequent occurrence of clinically actionable somatic mutations in ...