Now showing items 1-16 of 16

    • The “ART” of Linkage: Pre-Treatment Loss to Care after HIV Diagnosis at Two PEPFAR Sites in Durban, South Africa 

      Losina, Elena; Bassett, Ingrid; Giddy, Janet; Chetty, Senica; Regan, Susan; Walensky, Rochelle; Ross, Douglas; Scott, Callie A.; Uhler, Lauren M.; Katz, Jeffrey; Holst, Helga; Freedberg, Kenneth (Public Library of Science (PLoS), 2010-03-04)
      Background Although loss to follow-up after antiretroviral therapy (ART) initiation is increasingly recognized, little is known about pre-treatment losses to care (PTLC) after an initial positive HIV test. Our objective ...
    • The Clinical and Economic Impact of Point-of-Care CD4 Testing in Mozambique and Other Resource-Limited Settings: A Cost-Effectiveness Analysis 

      Hyle, Emily P.; Jani, Ilesh V.; Lehe, Jonathan; Su, Amanda E.; Wood, Robin; Quevedo, Jorge; Losina, Elena; Bassett, Ingrid V.; Pei, Pamela P.; Paltiel, A. David; Resch, Stephen; Freedberg, Kenneth A.; Peter, Trevor; Walensky, Rochelle P. (Public Library of Science, 2014)
      Background: Point-of-care CD4 tests at HIV diagnosis could improve linkage to care in resource-limited settings. Our objective is to evaluate the clinical and economic impact of point-of-care CD4 tests compared to ...
    • Diagnostic Accuracy of a Point-of-Care Urine Test for Tuberculosis Screening Among Newly-Diagnosed HIV-Infected Adults: A Prospective, Clinic-Based Study 

      Drain, Paul K.; Losina, Elena; Coleman, Sharon M.; Giddy, Janet; Ross, Douglas; Katz, Jeffrey; Walensky, Rochelle; Freedberg, Kenneth; Bassett, Ingrid (Springer Science and Business Media LLC, 2014-02-26)
      Background A rapid diagnostic test for active tuberculosis (TB) at the clinical point-of-care could expedite case detection and accelerate TB treatment initiation. We assessed the diagnostic accuracy of a rapid urine ...
    • Drug-Resistant Tuberculosis among HIV-Infected Patients Starting Antiretroviral Therapy in Durban, South Africa 

      Hom, Jeffrey K.; Wang, Bingxia; Chetty, Senica; Giddy, Janet; Mazibuko, Matilda; Allen, Jenny; Walensky, Rochelle P.; Losina, Elena; Freedberg, Kenneth Alan; Bassett, Ingrid Valerie (Public Library of Science, 2012)
      Objective: To estimate the prevalence of drug-resistant tuberculosis (TB) and describe the resistance patterns in patients commencing antiretroviral therapy (ART) in an HIV clinic in Durban, South Africa. Design ...
    • Factors Associated with Self-Reported Repeat HIV Testing after a Negative Result in Durban, South Africa 

      Regan, Susan; Losina, Elena; Chetty, Senica; Giddy, Janet; Walensky, Rochelle P.; Ross, Douglas Sterling; Holst, Helga; Katz, Jeffrey Neil; Freedberg, Kenneth Alan; Bassett, Ingrid Valerie (Public Library of Science, 2013)
      Background: Routine screening for HIV infection leads to early detection and treatment. We examined patient characteristics associated with repeated screening in a high prevalence country. Methods: We analyzed data from a ...
    • High rates of unplanned interruptions from HIV care early after antiretroviral therapy initiation in Nigeria 

      Ahonkhai, Aimalohi A.; Banigbe, Bolanle; Adeola, Juliet; Onwuatuelo, Ifeyinwa; Bassett, Ingrid V.; Losina, Elena; Freedberg, Kenneth A.; Okonkwo, Prosper; Regan, Susan (BioMed Central, 2015)
      Background: Unplanned care interruption (UCI) challenges effective HIV treatment. We determined the frequency and risk factors for UCI in Nigeria. Methods: We conducted a retrospective-cohort study of adults initiating ...
    • Improving HIV Outcomes in Resource-Limited Countries: The Importance of Quality Indicators 

      Ahonkhai, Aimalohi A; Bassett, Ingrid Valerie; Ferris, Timothy Gregg; Freedberg, Kenneth Alan (BioMed Central, 2012)
      Background: Resource-limited countries increasingly depend on quality indicators to improve outcomes within HIV treatment programs, but indicators of program performance suitable for use at the local program level remain ...
    • The Linkage Outcomes of a Large-scale, Rapid Transfer of HIV-infected Patients From Hospital-based to Community-based Clinics in South Africa 

      Cloete, Christie; Regan, Susan; Giddy, Janet; Govender, Tessa; Erlwanger, Alison; Gaynes, Melanie R.; Freedberg, Kenneth A.; Katz, Jeffrey N.; Walensky, Rochelle P.; Losina, Elena; Bassett, Ingrid V. (Oxford University Press, 2014)
      Background: President's Emergency Plan for AIDS Relief (PEPFAR) funding changes have resulted in human immunodeficiency virus (HIV) clinic closures. We evaluated linkage to care following a large-scale patient transfer ...
    • Linkage to HIV, TB and Non-Communicable Disease Care from a Mobile Testing Unit in Cape Town, South Africa 

      Govindasamy, Darshini; Kranzer, Katharina; van Schaik, Nienke; Noubary, Farzad; Wood, Robin; Walensky, Rochelle P.; Freedberg, Kenneth A.; Bassett, Ingrid V.; Bekker, Linda-Gail (Public Library of Science, 2013)
      Background: HIV counseling and testing may serve as an entry point for non-communicable disease screening. Objectives: To determine the yield of newly-diagnosed HIV, tuberculosis (TB) symptoms, diabetes and hypertension, ...
    • Mobile HIV Screening in Cape Town, South Africa: Clinical Impact, Cost and Cost-Effectiveness 

      Bassett, Ingrid V.; Govindasamy, Darshini; Erlwanger, Alison S.; Hyle, Emily P.; Kranzer, Katharina; van Schaik, Nienke; Noubary, Farzad; Paltiel, A. David; Wood, Robin; Walensky, Rochelle P.; Losina, Elena; Bekker, Linda-Gail; Freedberg, Kenneth A. (Public Library of Science, 2014)
      Background: Mobile HIV screening may facilitate early HIV diagnosis. Our objective was to examine the cost-effectiveness of adding a mobile screening unit to current medical facility-based HIV testing in Cape Town, South ...
    • Predictors of HIV infection: a prospective HIV screening study in a Ugandan refugee settlement 

      O’Laughlin, Kelli N.; Rabideau, Dustin J.; Kasozi, Julius; Parker, Robert A.; Bustamante, Nirma D.; Faustin, Zikama M.; Greenwald, Kelsy E.; Walensky, Rochelle P.; Bassett, Ingrid V. (BioMed Central, 2016)
      Background: The instability faced by refugees may place them at increased risk of exposure to HIV infection. Nakivale Refugee Settlement in southwestern Uganda hosts 68,000 refugees from 11 countries, many with high HIV ...
    • A randomized trial to optimize HIV/TB care in South Africa: design of the Sizanani trial 

      Bassett, Ingrid V; Giddy, Janet; Chaisson, Christine E; Ross, Douglas; Bogart, Laura M; Coleman, Sharon M; Govender, Tessa; Robine, Marion; Erlwanger, Alison; Freedberg, Kenneth A; Katz, Jeffrey N; Walensky, Rochelle P; Losina, Elena (BioMed Central, 2013)
      Background: Despite increases in HIV testing, only a fraction of people newly diagnosed with HIV infection enter the care system and initiate antiretroviral therapy (ART) in South Africa. We report on the design and initial ...
    • Rapid urine lipoarabinomannan assay as a clinic-based screening test for active tuberculosis at HIV diagnosis 

      Drain, Paul K.; Losina, Elena; Coleman, Sharon M.; Giddy, Janet; Ross, Douglas; Katz, Jeffrey N.; Bassett, Ingrid V. (BioMed Central, 2016)
      Background: World Health Organization (WHO) recommends tuberculosis (TB) screening at HIV diagnosis. We evaluated the inclusion of rapid urine lipoarabinomannan (LAM) testing in TB screening algorithms. Methods: We enrolled ...
    • Risk Factors for Late-Stage HIV Disease Presentation at Initial HIV Diagnosis in Durban, South Africa 

      Drain, Paul; Losina, Elena; Parker, Gary; Giddy, Janet; Ross, Douglas; Katz, Jeffrey Neil; Coleman, Sharon M.; Bogart, Laura M.; Freedberg, Kenneth A.; Walensky, Rochelle P.; Bassett, Ingrid Valerie (Public Library of Science, 2013)
      Background: After observing persistently low CD4 counts at initial HIV diagnosis in South Africa, we sought to determine risk factors for late-stage HIV disease presentation among adults. Methods: We surveyed adults prior ...
    • Routine HIV Testing in Adolescents and Young Adults Presenting to an Outpatient Clinic in Durban, South Africa 

      Ramirez-Avila, Lynn; Nixon, Kristy; Noubary, Farzad; Giddy, Janet; Losina, Elena; Walensky, Rochelle P.; Bassett, Ingrid Valerie (Public Library of Science, 2012)
      Objectives: Although youth (12–24 years) in Sub-Saharan Africa have a high HIV risk, many have poor access to HIV testing services and are unaware of their status. Our objective was to evaluate the proportion of adolescents ...
    • Sizanani: A Randomized Trial of Health System Navigators to Improve Linkage to HIV and TB Care in South Africa 

      Bassett, Ingrid V.; Coleman, Sharon M.; Giddy, Janet; Bogart, Laura M.; Chaisson, Christine E.; Ross, Douglas; Jacobsen, Margo M.; Robine, Marion; Govender, Tessa; Freedberg, Kenneth A.; Katz, Jeffrey N.; Walensky, Rochelle P.; Losina, Elena (JAIDS Journal of Acquired Immune Deficiency Syndromes, 2016)
      Background: A fraction of HIV-diagnosed individuals promptly initiate antiretroviral therapy (ART). We evaluated the efficacy of health system navigators for improving linkage to HIV and tuberculosis (TB) care among newly ...