Now showing items 1-2 of 2

    • A neural basis for melanocortin-4 receptor regulated appetite 

      Garfield, Alastair S.; Li, Chia; Madara, Joseph C.; Shah, Bhavik P.; Webber, Emily; Steger, Jennifer S.; Campbell, John N.; Gavrilova, Oksana; Lee, Charlotte E.; Olson, David P.; Elmquist, Joel K.; Tannous, Bakhos A.; Krashes, Michael J.; Lowell, Bradford B. (2015)
      Pro-opiomelanocortin (POMC)- and agouti-related peptide (AgRP)-expressing neurons are oppositely regulated by caloric depletion and co-ordinately stimulate and inhibit homeostatic satiety, respectively. This bimodality is ...
    • A Novel Excitatory Paraventricular Nucleus to AgRP Neuron Circuit that Drives Hunger 

      Krashes, Michael J.; Shah, Bhavik P.; Madara, Joseph C.; Olson, David P.; Strochlic, David E.; Garfield, Alastair S.; Vong, Linh; Pei, Hongjuan; Watabe-Uchida, Mitsuko; Uchida, Naoshige; Liberles, Stephen D.; Lowel, Bradford B. (2014)
      Summary Hunger is a hard-wired motivational state essential for survival. Agouti-related peptide (AgRP)-expressing neurons in the arcuate nucleus (ARC) at the base of the hypothalamus are crucial to its control. They are ...