Now showing items 1-7 of 7

    • Bioenergetic Measurements in Children with Bipolar Disorder: A Pilot \(^{31}\)P Magnetic Resonance Spectroscopy Study 

      Sikoglu, Elif M.; Jensen, John Eric; Vitaliano, Gordana Dragan; Liso Navarro, Ana A.; Renshaw, Perry Franklin; Frazier, Jean A.; Moore, Constance M. (Public Library of Science, 2013)
      Background: Research exploring Bipolar Disorder (BD) phenotypes and mitochondrial dysfunction, particularly in younger subjects, has been insufficient to date. Previous studies have found abnormal cerebral pH levels in ...
    • Brain Activation During Working Memory Is Altered in Patients With Type 1 Diabetes During Hypoglycemia 

      Bolo, Nicolas R.; Musen, Gail; Jacobson, Alan Marc; Weinger, Katie; McCartney, Richard L.; Flores, Veronica; Renshaw, Perry Franklin; Simonson, Donald Craig (American Diabetes Association, 2011)
      OBJECTIVE To investigate the effects of acute hypoglycemia on working memory and brain function in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS Using blood oxygen level–dependent (BOLD) functional magnetic ...
    • Effects of Sleep Deprivation on Brain Bioenergetics, Sleep, and Cognitive Performance in Cocaine-Dependent Individuals 

      Trksak, George H.; Bracken, Bethany K.; Jensen, J. Eric; Plante, David T.; Penetar, David M.; Tartarini, Wendy L.; Maywalt, Melissa A.; Dorsey, Cynthia M.; Renshaw, Perry F.; Lukas, Scott E. (Hindawi Publishing Corporation, 2013)
      In cocaine-dependent individuals, sleep is disturbed during cocaine use and abstinence, highlighting the importance of examining the behavioral and homeostatic response to acute sleep loss in these individuals. The current ...
    • Excitatory Neurotransmitters in Brain Regions in Interictal Migraine Patients 

      Prescot, Andrew; Becerra, Lino Renan; Pendse, Gautam; Tully, Shannon; Jensen, Eric; Hargreaves, Richard; Renshaw, Perry Franklin; Burstein, Rami; Borsook, David (BioMed Central, 2009)
      Objective: To examine biochemical differences in the anterior cingulate cortex (ACC) and insula during the interictal phase of migraine patients. We hypothesized that there may be differences in levels of excitatory amino ...
    • A Longitudinal Pilot Proton MRS Investigation of the Manic and Euthymic States of Bipolar Disorder 

      Brady, Roscoe Owen; Cooper, Anne; Jensen, John Eric; Tandon, Neeraj; Cohen, Bruce Michael; Renshaw, Perry Franklin; Keshavan, Matcheri S; Öngür, Dost (Nature Publishing Group, 2012)
      Several lines of evidence implicate dysfunction in brain energy production as a key component of bipolar disorder. In particular, elevated brain lactate levels observed in this condition suggest a shift from aerobic to ...
    • New Clathrin-Based Nanoplatforms for Magnetic Resonance Imaging 

      Vitaliano, Franco; Vitaliano, Gordana Dragan; Rios, Jose D.; Renshaw, Perry Franklin; Teicher, Martin Hersch (Public Library of Science, 2012)
      Background: Magnetic Resonance Imaging (MRI) has high spatial resolution, but low sensitivity for visualization of molecular targets in the central nervous system (CNS). Our goal was to develop a new MRI method with the ...
    • Reduced T2* Values in Soleus Muscle of Patients with Type 2 Diabetes Mellitus 

      Sung, Young-Hoon; Habecker, Erin; Haws, Charlotte; Villafuerte, Rosemond A.; Dobbins, Robert L.; Hodge, Rebecca J.; Nunez, Derek J. R.; Zuo, Chun S.; Simonson, Donald Craig; Wang, Jian; Henry, Michael; Renshaw, Perry Franklin (Public Library of Science, 2012)
      Tissue water transverse relaxation times (T2) are highly sensitive to fluid and lipid accumulations in skeletal muscles whereas the related T2* is sensitive to changes in tissue oxygenation in addition to factors affecting ...