Now showing items 1-2 of 2

    • Hin-Mediated DNA Knotting and Recombining Promote Replicon Dysfunction and Mutation 

      Deibler, Richard Wendel; Mann, Jennifer K.; Sumners, De Witt L.; Zechiedrich, Lynn (BioMed Central, 2007)
      Background: The genetic code imposes a dilemma for cells. The DNA must be long enough to encode for the complexity of an organism, yet thin and flexible enough to fit within the cell. The combination of these properties ...
    • The Why and How of DNA Unlinking 

      Liu, Zhirong; Deibler, Richard Wendel; Chan, Hue Sun; Zechiedrich, Lynn (Oxford University Press, 2009)
      The nucleotide sequence of DNA is the repository of hereditary information. Yet, it is now clear that the DNA itself plays an active role in regulating the ability of the cell to extract its information. Basic biological ...