Now showing items 1-20 of 67

    • ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: A comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas 

      Johnatty, Sharon E.; Beesley, Jonathan; Gao, Bo; Chen, Xiaoqing; Lu, Yi; Law, Matthew H.; Henderson, Michelle J.; Russell, Amanda J.; Hedditch, Ellen L.; Emmanuel, Catherine; Fereday, Sian; Webb, Penelope M.; Goode, Ellen L.; Vierkant, Robert A.; Fridley, Brooke L.; Cunningham, Julie M; Fasching, Peter A.; Beckmann, Matthias W.; Ekici, Arif B.; Hogdall, Estrid; Kjaer, Susanne K.; Jensen, Allan; Hogdall, Claus; Brown, Robert; Paul, Jim; Lambrechts, Sandrina; Despierre, Evelyn; Vergote, Ignace; Lester, Jenny; Karlan, Beth Y.; Heitz, Florian; du Bois, Andreas; Harter, Philipp; Schwaab, Ira; Bean, Yukie; Pejovic, Tanja; Levine, Douglas A.; Goodman, Marc T.; Camey, Michael E.; Thompson, Pamela J.; Lurie, Galina; Shildkraut, Joellen; Berchuck, Andrew; Terry, Kathryn Lynne; Cramer, Daniel William; Norris, Murray D.; Haber, Michelle; MacGregor, Stuart; deFazio, Anna; Chenevix-Trench, Georgia (Elsevier BV, 2013)
      Objective ABCB1 encodes the multi-drug efflux pump P-glycoprotein (P-gp) and has been implicated in multi-drug resistance. We comprehensively evaluated this gene and flanking regions for an association with clinical ...
    • ABO blood group and risk of epithelial ovarian cancer within the Ovarian Cancer Association Consortium 

      Poole, Elizabeth M.; Gates, Margaret A.; High, Brigit A.; Chanock, Stephen J.; Cramer, Daniel William; Cunningham, Julie M.; Fridley, Brooke L.; Gayther, Simon A.; Goode, Ellen L.; Iversen, Edwin S.; Lissowska, Jolanta; Weber, Rachel T. Palmieri; Pharoah, Paul D. P.; Phelan, Catherine M.; Ramus, Susan J.; Schildkraut, Joellen M.; Sutphen, Rebecca; Tsai, Ya-Yu; Tyrer, Jonathan; Vierkant, Robert A.; Wentzensen, Nicolas; Yang, Hannah P.; Terry, Kathryn Lynne; Tworoger, Shelley Slate (Springer Science + Business Media, 2012)
      Purpose Previous studies have examined the association between ABO blood group and ovarian cancer risk, with inconclusive results. Methods In 8 studies participating in the Ovarian Cancer Association Consortium ...
    • Analysis of Over 10,000 Cases Finds No Association between Previously Reported Candidate Polymorphisms and Ovarian Cancer Outcome 

      White, K. L.; Vierkant, R. A.; Fogarty, Z. C.; Charbonneau, B.; Block, M. S.; Pharoah, P. D. P.; Chenevix-Trench, G.; Rossing, M. A.; Cramer, Daniel William; Pearce, C. L.; Schildkraut, J. M.; Menon, U.; Kjaer, S. K.; Levine, D. A.; Gronwald, J.; Culver, H. A.; Whittemore, A. S.; Karlan, B. Y.; Lambrechts, D.; Wentzensen, N.; Kupryjanczyk, J.; Chang-Claude, J.; Bandera, E. V.; Hogdall, E.; Heitz, F.; Kaye, S. B.; Fasching, P. A.; Campbell, I.; Goodman, M. T.; Pejovic, T.; Bean, Y.; Lurie, G.; Eccles, D.; Hein, A.; Beckmann, M. W.; Ekici, A. B.; Paul, J.; Brown, R.; Flanagan, J. M.; Harter, P.; du Bois, A.; Schwaab, I.; Hogdall, C. K.; Lundvall, L.; Olson, S. H.; Orlow, I.; Paddock, L. E.; Rudolph, A.; Eilber, U.; Dansonka-Mieszkowska, A.; Rzepecka, I. K.; Ziolkowska-Seta, I.; Brinton, L.; Yang, H.; Garcia-Closas, M.; Despierre, E.; Lambrechts, S.; Vergote, I.; Walsh, C.; Lester, J.; Sieh, W.; McGuire, V.; Rothstein, J. H.; Ziogas, A.; Lubinski, J.; Cybulski, C.; Menkiszak, J.; Jensen, A.; Gayther, S. A.; Ramus, S. J.; Gentry-Maharaj, A.; Berchuck, A.; Wu, A. H.; Pike, M. C.; Van DenBerg, D.; Terry, Kathryn Lynne; Vitonis, A. F.; Doherty, J. A.; Johnatty, S. E.; deFazio, A.; Song, H.; Tyrer, J.; Sellers, T. A.; Phelan, C. M.; Kalli, K. R.; Cunningham, J. M.; Fridley, B. L.; Goode, E. L. (American Association for Cancer Research (AACR), 2013)
      Background Ovarian cancer is a leading cause of cancer-related death among women. In an effort to understand contributors to disease outcome, we evaluated single-nucleotide polymorphisms (SNPs) previously associated ...
    • Androgen Receptor Cytosine, Adenine, Guanine Repeats, and Haplotypes in Relation to Ovarian Cancer Risk 

      Terry, Kathryn Lynne; De Vivo, Immaculata; Titus-Ernstoff, Linda; Shih, Mei-Chiung; Cramer, Daniel William (American Association for Cancer Research (AACR), 2005)
      Biological and epidemiologic evidence suggest that androgen or its receptor may play a role in ovarian cancer pathogenesis. The most notable genetic factor influencing androgen receptor (AR) activity is the functional ...
    • Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk 

      Lee, Alice W.; Ness, Roberta B.; Roman, Lynda D.; Terry, Kathryn Lynne; Schildkraut, Joellen M.; Chang-Claude, Jenny; Doherty, Jennifer A.; Menon, Usha; Cramer, Daniel William; Gayther, Simon A.; Risch, Harvey; Gentry-Maharaj, Aleksandra; Goodman, Marc T.; Modugno, Francesmary; Eilber, Ursula; Moysich, Kirsten B.; Berchuck, Andrew; Rossing, Mary Anne; Jensen, Allan; Wicklund, Kristine G.; Cushing-Haugen, Kara L.; Hogdall, Estrid; Rudolph, Anja; Thompson, Pamela J.; Wilkens, Lynne R.; Kjaer, Susanne K.; Carney, Michael E.; Stram, Daniel O.; Ramus, Susan J.; Wu, Anna H.; Pike, Malcolm C.; Pearce, Celeste Leigh (Ovid Technologies (Wolters Kluwer Health), 2016)
      OBJECTIVE: To describe the association between postmenopausal estrogen-only therapy use and risk of ovarian carcinoma, specifically with regard to disease histotype and duration and timing of use. METHODS: We conducted a ...
    • The association between socioeconomic status and tumour stage at diagnosis of ovarian cancer: A pooled analysis of 18 case-control studies 

      Præstegaard, Camilla; Kjaer, Susanne K.; Nielsen, Thor S.S.; Jensen, Signe M.; Webb, Penelope M.; Nagle, Christina M.; Høgdall, Estrid; Risch, Harvey A.; Rossing, Mary Anne; Doherty, Jennifer A.; Wicklund, Kristine G.; Goodman, Marc T.; Modugno, Francesmary; Moysich, Kirsten; Ness, Roberta B.; Edwards, Robert P.; Goode, Ellen L.; Winham, Stacey J.; Fridley, Brooke L.; Cramer, Daniel William; Terry, Kathryn Lynne; Schildkraut, Joellen M.; Berchuck, Andrew; Bandera, Elisa V.; Paddock, Lisa; Kiemeney, Lambertus A.; Massuger, Leon F.; Wentzensen, Nicolas; Pharoah, Paul; Song, Honglin; Whittemore, Alice S.; McGuire, Valerie; Sieh, Weiva; Rothstein, Joseph; Anton-Culver, Hoda; Ziogas, Argyrios; Menon, Usha; Gayther, Simon A.; Ramus, Susan J.; Gentry-Maharaj, Aleksandra; Wu, Anna H.; Pearce, Celeste L.; Pike, Malcolm C.; Lee, Alice W.; Chang-Claude, Jenny; Jensen, Allan (Elsevier BV, 2016)
      PURPOSE: Socioeconomic status (SES) is a known predictor of survival for several cancers and it has been suggested that SES differences affecting tumour stage at diagnosis may be the most important explanatory factor for ...
    • The Association Between Talc Use and Ovarian Cancer 

      Cramer, Daniel William; Vitonis, Allison F.; Terry, Kathryn Lynne; Welch, William Robert; Titus, Linda J. (Ovid Technologies (Wolters Kluwer Health), 2016)
      BACKGROUND: Multiple studies of ovarian cancer and genital talc use have led only to consensus about possible carcinogenicity. Seeking greater clarity, we examined this association in 2,041 cases with epithelial ovarian ...
    • The Association Between Talc Use and Ovarian Cancer: A Retrospective Case–Control Study in Two US States 

      Cramer, Daniel W.; Vitonis, Allison F.; Terry, Kathryn L.; Welch, William R.; Titus, Linda J. (Lippincott Williams & Wilkins, 2015)
      Background: Multiple studies of ovarian cancer and genital talc use have led only to consensus about possible carcinogenicity. Seeking greater clarity, we examined this association in 2,041 cases with epithelial ovarian ...
    • Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populations 

      Gates, Margaret A.; Tworoger, Shelley Slate; Terry, Kathryn Lynne; De Vivo, Immaculata; Hunter, David J.; Hankinson, Susan Elizabeth; Cramer, Daniel William (Wiley-Blackwell, 2009)
      Recent genome-wide scans identified several novel breast cancer risk alleles, including variants of the FGFR2, MAP3K1, and LSP1 genes, and a study of associations between these alleles and characteristics of breast cancer ...
    • Breast-feeding the last born child and risk of ovarian cancer 

      Titus-Ernstoff, Linda; Rees, Judy R.; Terry, Kathryn Lynne; Cramer, Daniel William (Springer Science + Business Media, 2009)
      Conflicting reports regarding the relationship between breast-feeding and ovarian cancer risk suggest a possible influence of patterns of breast-feeding. We used logistic regression to examine breast-feeding in a large ...
    • Cigarette smoking and risk of ovarian cancer: a pooled analysis of 21 case–control studies 

      Faber, Mette T.; Kjær, Susanne K.; Dehlendorff, Christian; Chang-Claude, Jenny; Andersen, Klaus K.; Høgdall, Estrid; Webb, Penelope M.; Jordan, Susan J.; Rossing, Mary Anne; Doherty, Jennifer A.; Lurie, Galina; Thompson, Pamela J.; Carney, Michael E.; Goodman, Marc T.; Ness, Roberta B.; Modugno, Francesmary; Edwards, Robert P.; Bunker, Clareann H.; Goode, Ellen L.; Fridley, Brooke L.; Vierkant, Robert A.; Larson, Melissa C.; Schildkraut, Joellen; Cramer, Daniel William; Terry, Kathryn Lynne; Vitonis, Allison F.; Bandera, Elisa V.; Olson, Sara H.; King, Melony; Chandran, Urmila; Kiemeney, Lambertus A.; Massuger, Leon F. A. G.; van Altena, Anne M.; Vermeulen, Sita H.; Brinton, Louise; Wentzensen, Nicolas; Lissowska, Jolanta; Yang, Hannah P.; Moysich, Kirsten B.; Odunsi, Kunle; Kasza, Karin; Odunsi-Akanji, Oluwatosin; Song, Honglin; Pharaoh, Paul; Shah, Mitul; Whittemore, Alice S.; McGuire, Valerie; Sieh, Weiva; Sutphen, Rebecca; Menon, Usha; Gayther, Simon A.; Ramus, Susan J.; Gentry-Maharaj, Aleksandra; Pearce, Celeste Leigh; Wu, Anna H.; Pike, Malcolm C.; Risch, Harvey A.; Jensen, Allan (Springer Science + Business Media, 2013)
      Purpose The majority of previous studies have observed an increased risk of mucinous ovarian tumors associated with cigarette smoking, but the association with other histological types is unclear. In a large pooled ...
    • Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer 

      Lawrenson, Kate; Li, Qiyuan; Kar, Siddhartha; Seo, Ji-Heui; Tyrer, Jonathan; Spindler, Tassja J.; Lee, Janet; Chen, Yibu; Karst, Alison; Drapkin, Ronny; Aben, Katja K. H.; Anton-Culver, Hoda; Antonenkova, Natalia; Bowtell, David; Webb, Penelope M.; deFazio, Anna; Baker, Helen; Bandera, Elisa V.; Bean, Yukie; Beckmann, Matthias W.; Berchuck, Andrew; Bisogna, Maria; Bjorge, Line; Bogdanova, Natalia; Brinton, Louise A.; Brooks-Wilson, Angela; Bruinsma, Fiona; Butzow, Ralf; Campbell, Ian G.; Carty, Karen; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Chen, Anne; Chen, Zhihua; Cook, Linda S.; Cramer, Daniel W.; Cunningham, Julie M.; Cybulski, Cezary; Dansonka-Mieszkowska, Agnieszka; Dennis, Joe; Dicks, Ed; Doherty, Jennifer A.; Dörk, Thilo; du Bois, Andreas; Dürst, Matthias; Eccles, Diana; Easton, Douglas T.; Edwards, Robert P.; Eilber, Ursula; Ekici, Arif B.; Fasching, Peter A.; Fridley, Brooke L.; Gao, Yu-Tang; Gentry-Maharaj, Aleksandra; Giles, Graham G.; Glasspool, Rosalind; Goode, Ellen L.; Goodman, Marc T.; Grownwald, Jacek; Harrington, Patricia; Harter, Philipp; Hasmad, Hanis Nazihah; Hein, Alexander; Heitz, Florian; Hildebrandt, Michelle A. T.; Hillemanns, Peter; Hogdall, Estrid; Hogdall, Claus; Hosono, Satoyo; Iversen, Edwin S.; Jakubowska, Anna; James, Paul; Jensen, Allan; Ji, Bu-Tian; Karlan, Beth Y.; Kruger Kjaer, Susanne; Kelemen, Linda E.; Kellar, Melissa; Kelley, Joseph L.; Kiemeney, Lambertus A.; Krakstad, Camilla; Kupryjanczyk, Jolanta; Lambrechts, Diether; Lambrechts, Sandrina; Le, Nhu D.; Lee, Alice W.; Lele, Shashi; Leminen, Arto; Lester, Jenny; Levine, Douglas A.; Liang, Dong; Lissowska, Jolanta; Lu, Karen; Lubinski, Jan; Lundvall, Lene; Massuger, Leon F. A. G.; Matsuo, Keitaro; McGuire, Valerie; McLaughlin, John R.; Nevanlinna, Heli; McNeish, Ian; Menon, Usha; Modugno, Francesmary; Moysich, Kirsten B.; Narod, Steven A.; Nedergaard, Lotte; Ness, Roberta B.; Azmi, Mat Adenan Noor; Odunsi, Kunle; Olson, Sara H.; Orlow, Irene; Orsulic, Sandra; Weber, Rachel Palmieri; Pearce, Celeste L.; Pejovic, Tanja; Pelttari, Liisa M.; Permuth-Wey, Jennifer; Phelan, Catherine M.; Pike, Malcolm C.; Poole, Elizabeth M.; Ramus, Susan J.; Risch, Harvey A.; Rosen, Barry; Rossing, Mary Anne; Rothstein, Joseph H.; Rudolph, Anja; Runnebaum, Ingo B.; Rzepecka, Iwona K.; Salvesen, Helga B.; Schildkraut, Joellen M.; Schwaab, Ira; Sellers, Thomas A.; Shu, Xiao-Ou; Shvetsov, Yurii B.; Siddiqui, Nadeem; Sieh, Weiva; Song, Honglin; Southey, Melissa C.; Sucheston, Lara; Tangen, Ingvild L.; Teo, Soo-Hwang; Terry, Kathryn L.; Thompson, Pamela J.; Timorek, Agnieszka; Tsai, Ya-Yu; Tworoger, Shelley S.; van Altena, Anne M.; Van Nieuwenhuysen, Els; Vergote, Ignace; Vierkant, Robert A.; Wang-Gohrke, Shan; Walsh, Christine; Wentzensen, Nicolas; Whittemore, Alice S.; Wicklund, Kristine G.; Wilkens, Lynne R.; Woo, Yin-Ling; Wu, Xifeng; Wu, Anna H.; Yang, Hannah; Zheng, Wei; Ziogas, Argyrios; Monteiro, Alvaro; Pharoah, Paul D.; Gayther, Simon A.; Freedman, Matthew L. (Nature Pub. Group, 2015)
      Genome-wide association studies have reported 11 regions conferring risk of high-grade serous epithelial ovarian cancer (HGSOC). Expression quantitative trait locus (eQTL) analyses can identify candidate susceptibility ...
    • Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancer 

      Kotsopoulos, Joanne; Vitonis, Allison F.; Terry, Kathryn Lynne; De Vivo, Immaculata; Cramer, Daniel William; Hankinson, Susan Elizabeth; Tworoger, Shelley Slate (Springer Science + Business Media, 2008)
      We evaluated whether genetic variability, as well as menopausal status, modify the association between coffee intake and risk of ovarian cancer. Risk factor information and biologic specimens from three large epidemiological ...
    • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk 

      Chornokur, Ganna; Lin, Hui-Yi; Tyrer, Jonathan P.; Lawrenson, Kate; Dennis, Joe; Amankwah, Ernest K.; Qu, Xiaotao; Tsai, Ya-Yu; Jim, Heather S. L.; Chen, Zhihua; Chen, Ann Y.; Permuth-Wey, Jennifer; Aben, Katja KH.; Anton-Culver, Hoda; Antonenkova, Natalia; Bruinsma, Fiona; Bandera, Elisa V.; Bean, Yukie T.; Beckmann, Matthias W.; Bisogna, Maria; Bjorge, Line; Bogdanova, Natalia; Brinton, Louise A.; Brooks-Wilson, Angela; Bunker, Clareann H.; Butzow, Ralf; Campbell, Ian G.; Carty, Karen; Chang-Claude, Jenny; Cook, Linda S.; Cramer, Daniel W.; Cunningham, Julie M.; Cybulski, Cezary; Dansonka-Mieszkowska, Agnieszka; du Bois, Andreas; Despierre, Evelyn; Dicks, Ed; Doherty, Jennifer A.; Dörk, Thilo; Dürst, Matthias; Easton, Douglas F.; Eccles, Diana M.; Edwards, Robert P.; Ekici, Arif B.; Fasching, Peter A.; Fridley, Brooke L.; Gao, Yu-Tang; Gentry-Maharaj, Aleksandra; Giles, Graham G.; Glasspool, Rosalind; Goodman, Marc T.; Gronwald, Jacek; Harrington, Patricia; Harter, Philipp; Hein, Alexander; Heitz, Florian; Hildebrandt, Michelle A. T.; Hillemanns, Peter; Hogdall, Claus K.; Hogdall, Estrid; Hosono, Satoyo; Jakubowska, Anna; Jensen, Allan; Ji, Bu-Tian; Karlan, Beth Y.; Kelemen, Linda E.; Kellar, Mellissa; Kiemeney, Lambertus A.; Krakstad, Camilla; Kjaer, Susanne K.; Kupryjanczyk, Jolanta; Lambrechts, Diether; Lambrechts, Sandrina; Le, Nhu D.; Lee, Alice W.; Lele, Shashi; Leminen, Arto; Lester, Jenny; Levine, Douglas A.; Liang, Dong; Lim, Boon Kiong; Lissowska, Jolanta; Lu, Karen; Lubinski, Jan; Lundvall, Lene; Massuger, Leon F. A. G.; Matsuo, Keitaro; McGuire, Valerie; McLaughlin, John R.; McNeish, Iain; Menon, Usha; Milne, Roger L.; Modugno, Francesmary; Moysich, Kirsten B.; Ness, Roberta B.; Nevanlinna, Heli; Eilber, Ursula; Odunsi, Kunle; Olson, Sara H.; Orlow, Irene; Orsulic, Sandra; Weber, Rachel Palmieri; Paul, James; Pearce, Celeste L.; Pejovic, Tanja; Pelttari, Liisa M.; Pike, Malcolm C.; Poole, Elizabeth M.; Risch, Harvey A.; Rosen, Barry; Rossing, Mary Anne; Rothstein, Joseph H.; Rudolph, Anja; Runnebaum, Ingo B.; Rzepecka, Iwona K.; Salvesen, Helga B.; Schernhammer, Eva; Schwaab, Ira; Shu, Xiao-Ou; Shvetsov, Yurii B.; Siddiqui, Nadeem; Sieh, Weiva; Song, Honglin; Southey, Melissa C.; Spiewankiewicz, Beata; Sucheston, Lara; Teo, Soo-Hwang; Terry, Kathryn L.; Thompson, Pamela J.; Thomsen, Lotte; Tangen, Ingvild L.; Tworoger, Shelley S.; van Altena, Anne M.; Vierkant, Robert A.; Vergote, Ignace; Walsh, Christine S.; Wang-Gohrke, Shan; Wentzensen, Nicolas; Whittemore, Alice S.; Wicklund, Kristine G.; Wilkens, Lynne R.; Wu, Anna H.; Wu, Xifeng; Woo, Yin-Ling; Yang, Hannah; Zheng, Wei; Ziogas, Argyrios; Hasmad, Hanis N.; Berchuck, Andrew; Iversen, Edwin S.; Schildkraut, Joellen M.; Ramus, Susan J.; Goode, Ellen L.; Monteiro, Alvaro N. A.; Gayther, Simon A.; Narod, Steven A.; Pharoah, Paul D. P.; Sellers, Thomas A.; Phelan, Catherine M. (Public Library of Science, 2015)
      Background: Defective cellular transport processes can lead to aberrant accumulation of trace elements, iron, small molecules and hormones in the cell, which in turn may promote the formation of reactive oxygen species, ...
    • Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC) 

      Jim, Heather S.L.; Lin, Hui-Yi; Tyrer, Jonathan P.; Lawrenson, Kate; Dennis, Joe; Chornokur, Ganna; Chen, Zhihua; Chen, Ann Y.; Permuth-Wey, Jennifer; Aben, Katja KH.; Anton-Culver, Hoda; Antonenkova, Natalia; Bruinsma, Fiona; Bandera, Elisa V.; Bean, Yukie T.; Beckmann, Matthias W.; Bisogna, Maria; Bjorge, Line; Bogdanova, Natalia; Brinton, Louise A.; Brooks-Wilson, Angela; Bunker, Clareann H.; Butzow, Ralf; Campbell, Ian G.; Carty, Karen; Chang-Claude, Jenny; Cook, Linda S.; Cramer, Daniel W.; Cunningham, Julie M.; Cybulski, Cezary; Dansonka-Mieszkowska, Agnieszka; du Bois, Andreas; Despierre, Evelyn; Sieh, Weiva; Doherty, Jennifer A.; Dörk, Thilo; Dürst, Matthias; Easton, Douglas F.; Eccles, Diana M.; Edwards, Robert P.; Ekici, Arif B.; Fasching, Peter A.; Fridley, Brooke L.; Gao, Yu-Tang; Gentry-Maharaj, Aleksandra; Giles, Graham G.; Glasspool, Rosalind; Goodman, Marc T.; Gronwald, Jacek; Harter, Philipp; Hasmad, Hanis N.; Hein, Alexander; Heitz, Florian; Hildebrandt, Michelle A.T.; Hillemanns, Peter; Hogdall, Claus K.; Hogdall, Estrid; Hosono, Satoyo; Iversen, Edwin S.; Jakubowska, Anna; Jensen, Allan; Ji, Bu-Tian; Karlan, Beth Y.; Kellar, Melissa; Kiemeney, Lambertus A.; Krakstad, Camilla; Kjaer, Susanne K.; Kupryjanczyk, Jolanta; Vierkant, Robert A.; Lambrechts, Diether; Lambrechts, Sandrina; Le, Nhu D.; Lee, Alice W.; Lele, Shashi; Leminen, Arto; Lester, Jenny; Levine, Douglas A.; Liang, Dong; Lim, Boon Kiong; Lissowska, Jolanta; Lu, Karen; Lubinski, Jan; Lundvall, Lene; Massuger, Leon F.A.G.; Matsuo, Keitaro; McGuire, Valerie; McLaughlin, John R.; McNeish, Ian; Menon, Usha; Milne, Roger L.; Modugno, Francesmary; Thomsen, Lotte; Moysich, Kirsten B.; Ness, Roberta B.; Nevanlinna, Heli; Eilber, Ursula; Odunsi, Kunle; Olson, Sara H.; Orlow, Irene; Orsulic, Sandra; Palmieri Weber, Rachel; Paul, James; Pearce, Celeste L.; Pejovic, Tanja; Pelttari, Liisa M.; Pike, Malcolm C.; Poole, Elizabeth M.; Schernhammer, Eva; Risch, Harvey A.; Rosen, Barry; Rossing, Mary Anne; Rothstein, Joseph H.; Rudolph, Anja; Runnebaum, Ingo B.; Rzepecka, Iwona K.; Salvesen, Helga B.; Schwaab, Ira; Shu, Xiao-Ou; Shvetsov, Yurii B.; Siddiqui, Nadeem; Song, Honglin; Southey, Melissa C.; Spiewankiewicz, Beata; Sucheston-Campbell, Lara; Teo, Soo-Hwang; Terry, Kathryn L.; Thompson, Pamela J.; Tangen, Ingvild L.; Tworoger, Shelley S.; van Altena, Anne M.; Vergote, Ignace; Walsh, Christine S.; Wang-Gohrke, Shan; Wentzensen, Nicolas; Whittemore, Alice S.; Wicklund, Kristine G.; Wilkens, Lynne R.; Wu, Anna H.; Wu, Xifeng; Woo, Yin-Ling; Yang, Hannah; Zheng, Wei; Ziogas, Argyrios; Amankwah, Ernest; Berchuck, Andrew; Schildkraut, Joellen M.; Kelemen, Linda E.; Ramus, Susan J.; Monteiro, Alvaro N.A.; Goode, Ellen L.; Narod, Steven A.; Gayther, Simon A.; Pharoah, Paul D. P.; Sellers, Thomas A.; Phelan, Catherine M. (2016)
      Disruption in circadian gene expression, whether due to genetic variation or environmental factors (e.g., light at night, shiftwork), is associated with increased incidence of breast, prostate, gastrointestinal and hematologic ...
    • Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk 

      Terry, Kathryn Lynne; Tworoger, Shelley Slate; Gates, M. A.; Cramer, Daniel William; Hankinson, Susan Elizabeth (Oxford University Press (OUP), 2009)
      Insulin-like growth factor (IGF) 1 and its binding proteins foster cellular proliferation and inhibit apoptosis. In vitro studies show that IGF1 increases ovarian cell growth and invasive potential, suggesting a role for ...
    • Common variants at 19p13 are associated with susceptibility to ovarian cancer 

      Bolton, Kelly L; Tyrer, Jonathan; Song, Honglin; Ramus, Susan J; Notaridou, Maria; Jones, Chris; Sher, Tanya; Gentry-Maharaj, Aleksandra; Wozniak, Eva; Tsai, Ya-Yu; Weidhaas, Joanne; Paik, Daniel; Van Den Berg, David J; Stram, Daniel O; Pearce, Celeste Leigh; Wu, Anna H; Brewster, Wendy; Anton-Culver, Hoda; Ziogas, Argyrios; Narod, Steven A; Levine, Douglas A; Kaye, Stanley B; Brown, Robert; Paul, Jim; Flanagan, James; Sieh, Weiva; McGuire, Valerie; Whittemore, Alice S; Campbell, Ian; Gore, Martin E; Lissowska, Jolanta; Yang, Hanna P; Medrek, Krzysztof; Gronwald, Jacek; Lubinski, Jan; Jakubowska, Anna; Le, Nhu D; Cook, Linda S; Kelemen, Linda E; Brook-Wilson, Angela; Massuger, Leon F A G; Kiemeney, Lambertus A; Aben, Katja K H; van Altena, Anne M; Houlston, Richard; Tomlinson, Ian; Palmieri, Rachel T; Moorman, Patricia G; Schildkraut, Joellen; Iversen, Edwin S; Phelan, Catherine; Vierkant, Robert A; Cunningham, Julie M; Goode, Ellen L; Fridley, Brooke L; Kruger-Kjaer, Susan; Blaeker, Jan; Hogdall, Estrid; Hogdall, Claus; Gross, Jenny; Karlan, Beth Y; Ness, Roberta B; Edwards, Robert P; Odunsi, Kunle; Moyisch, Kirsten B; Baker, Julie A; Modugno, Francesmary; Heikkinenen, Tuomas; Butzow, Ralf; Nevanlinna, Heli; Leminen, Arto; Bogdanova, Natalia; Antonenkova, Natalia; Doerk, Thilo; Hillemanns, Peter; Dürst, Matthias; Runnebaum, Ingo; Thompson, Pamela J; Carney, Michael E; Goodman, Marc T; Lurie, Galina; Wang-Gohrke, Shan; Hein, Rebecca; Chang-Claude, Jenny; Rossing, Mary Anne; Cushing-Haugen, Kara L; Doherty, Jennifer; Chen, Chu; Rafnar, Thorunn; Besenbacher, Soren; Sulem, Patrick; Stefansson, Kari; Birrer, Michael James; Terry, Kathryn Lynne; Hernandez, Dena; Cramer, Daniel William; Vergote, Ignace; Amant, Frederic; Lambrechts, Diether; Despierre, Evelyn; Fasching, Peter A; Beckmann, Matthias W; Thiel, Falk C; Ekici, Arif B; Chen, Xiaoqing; Johnatty, Sharon E; Webb, Penelope M; Beesley, Jonathan; Chanock, Stephen; Garcia-Closas, Montserrat; Sellers, Tom; Easton, Douglas F; Berchuck, Andrew; Chenevix-Trench, Georgia; Pharoah, Paul D P; Gayther, Simon A (Nature Publishing Group, 2010)
      Epithelial ovarian cancer (EOC) is the leading cause of death from gynecological malignancy in the developed world accounting for 4 percent of deaths from cancer in women1. We performed a three-phase genome-wide association ...
    • Common variants at theCHEK2gene locus and risk of epithelial ovarian cancer 

      Lawrenson, Kate; Iversen, Edwin S.; Tyrer, Jonathan; Weber, Rachel Palmieri; Concannon, Patrick; Hazelett, Dennis J.; Li, Qiyuan; Marks, Jeffrey R.; Berchuck, Andrew; Lee, Janet M.; Aben, Katja K.H.; Anton-Culver, Hoda; Antonenkova, Natalia; Bandera, Elisa V.; Bean, Yukie; Beckmann, Matthias W.; Bisogna, Maria; Bjorge, Line; Bogdanova, Natalia; Brinton, Louise A.; Brooks-Wilson, Angela; Bruinsma, Fiona; Butzow, Ralf; Campbell, Ian G.; Carty, Karen; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Chen, Ann; Chen, Zhihua; Cook, Linda S.; Cramer, Daniel William; Cunningham, Julie M.; Cybulski, Cezary; Plisiecka-Halasa, Joanna; Dennis, Joe; Dicks, Ed; Doherty, Jennifer A.; Dörk, Thilo; du Bois, Andreas; Eccles, Diana; Easton, Douglas T.; Edwards, Robert P.; Eilber, Ursula; Ekici, Arif B.; Fasching, Peter A.; Fridley, Brooke L.; Gao, Yu-Tang; Gentry-Maharaj, Aleksandra; Giles, Graham G.; Glasspool, Rosalind; Goode, Ellen L.; Goodman, Marc T.; Gronwald, Jacek; Harter, Philipp; Hasmad, Hanis Nazihah; Hein, Alexander; Heitz, Florian; Hildebrandt, Michelle A.T.; Hillemanns, Peter; Hogdall, Estrid; Hogdall, Claus; Hosono, Satoyo; Jakubowska, Anna; Paul, James; Jensen, Allan; Karlan, Beth Y.; Kjaer, Susanne Kruger; Kelemen, Linda E.; Kellar, Melissa; Kelley, Joseph L.; Kiemeney, Lambertus A.; Krakstad, Camilla; Lambrechts, Diether; Lambrechts, Sandrina; Le, Nhu D.; Lee, Alice W.; Cannioto, Rikki; Leminen, Arto; Lester, Jenny; Levine, Douglas A.; Liang, Dong; Lissowska, Jolanta; Lu, Karen; Lubinski, Jan; Lundvall, Lene; Massuger, Leon F.A.G.; Matsuo, Keitaro; McGuire, Valerie; McLaughlin, John R.; Nevanlinna, Heli; McNeish, Iain; Menon, Usha; Modugno, Francesmary; Moysich, Kirsten B.; Narod, Steven A.; Nedergaard, Lotte; Ness, Roberta B.; Noor Azmi, Mat Adenan; Odunsi, Kunle; Olson, Sara H.; Orlow, Irene; Orsulic, Sandra; Pearce, Celeste L.; Pejovic, Tanja; Pelttari, Liisa M.; Permuth-Wey, Jennifer; Phelan, Catherine M.; Pike, Malcolm C.; Poole, Elizabeth M.; Ramus, Susan J.; Risch, Harvey A.; Rosen, Barry; Rossing, Mary Anne; Rothstein, Joseph H.; Rudolph, Anja; Runnebaum, Ingo B.; Rzepecka, Iwona K.; Salvesen, Helga B.; Budzilowska, Agnieszka; Sellers, Thomas A.; Shu, Xiao-Ou; Shvetsov, Yurii B.; Siddiqui, Nadeem; Sieh, Weiva; Song, Honglin; Southey, Melissa C.; Sucheston, Lara; Tangen, Ingvild L.; Teo, Soo-Hwang; Terry, Kathryn Lynne; Thompson, Pamela J.; Timorek, Agnieszka; Tworoger, Shelley Slate; Nieuwenhuysen, Els Van; Vergote, Ignace; Vierkant, Robert A.; Wang-Gohrke, Shan; Walsh, Christine; Wentzensen, Nicolas; Whittemore, Alice S.; Wicklund, Kristine G.; Wilkens, Lynne R.; Woo, Yin-Ling; Wu, Xifeng; Wu, Anna H.; Yang, Hannah; Zheng, Wei; Ziogas, Argyrios; Coetzee, Gerhard A.; Freedman, Matthew Lawrence; Monteiro, Alvaro N.A.; Moes-Sosnowska, Joanna; Kupryjanczyk, Jolanta; Pharoah, Paul D.; Gayther, Simon A.; Schildkraut, Joellen M. (Oxford University Press (OUP), 2015)
      Genome-wide association studies have identified 20 genomic regions associated with risk of epithelial ovarian cancer (EOC), but many additional risk variants may exist. Here, we evaluated associations between common genetic ...
    • Consortium analysis of 7 candidate SNPs for ovarian cancer 

      Ramus, Susan J.; Vierkant, Robert A.; Johnatty, Sharon E.; Pike, Malcolm C.; Van Den Berg, David J.; Wu, Anna H.; Pearce, Celeste Leigh; Menon, Usha; Gentry-Maharaj, Aleksandra; Gayther, Simon A.; DiCioccio, Richard A.; McGuire, Valerie; Whittemore, Alice S.; Song, Honglin; Easton, Douglas F.; Pharoah, Paul D.P.; Garcia-Closas, Montserrat; Chanock, Stephen; Lissowska, Jolanta; Brinton, Louise; Terry, Kathryn Lynne; Cramer, Daniel William; Tworoger, Shelley Slate; Hankinson, Susan Elizabeth; Berchuck, Andrew; Moorman, Patricia G.; Schildkraut, Joellen M.; Cunningham, Julie M.; Liebow, Mark; Kjaer, Susanne Krüger; Hogdall, Estrid; Hogdall, Claus; Blaakaer, Jan; Ness, Roberta B.; Moysich, Kirsten B.; Edwards, Robert P.; Carney, Michael E.; Lurie, Galina; Goodman, Marc T.; Wang-Gohrke, Shan; Kropp, Silke; Chang-Claude, Jenny; Webb, Penelope M.; Chen, Xiaoqing; Beesley, Jonathan; Chenevix-Trench, Georgia; Goode, Ellen L. (Wiley-Blackwell, 2008)
      The Ovarian Cancer Association Consortium selected 7 candidate single nucleotide polymorphisms (SNPs), for which there is evidence from previous studies of an association with variation in ovarian cancer or breast cancer ...
    • Correlates of the preoperative level of CA125 at presentation of ovarian cancer 

      Cramer, Daniel William; Vitonis, Allison F.; Welch, William Robert; Terry, Kathryn Lynne; Goodman, Annekathryn; Rueda, Bo Ruben; Berkowitz, Ross Stuart (Elsevier BV, 2010)
      Objective CA125 at presentation of ovarian cancer carries important prognostic significance; but, other than tumor characteristics, little is known about factors that influence CA125 levels. We examined the effect of ...