Browsing by Author "Weaver, James"
Now showing items 1-20 of 21
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Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses
Son, Reuben S.; Smith, Kyle C.; Gowrishankar, Thiruvallur R.; Vernier, P. Thomas; Weaver, James C. (Springer US, 2014)Science increasingly involves complex modeling. Here we describe a model for cell electroporation in which membrane properties are dynamically modified by poration. Spatial scales range from cell membrane thickness (5 nm) ... -
Biomimetic shark skin: design, fabrication and hydrodynamic function
Wen, L; Weaver, James C.; Lauder, George V. (The Company of Biologists, 2014)Although the functional properties of shark skin have been of considerable interest to both biologists and engineers because of the complex hydrodynamic effects of surface roughness, no study to date has successfully ... -
Bone Marrow–on–a–Chip Replicates Hematopoietic Niche Physiology in Vitro
Torisawa, Yu-suke; Spina, Catherine; Mammoto, Tadanori; Mammoto, Akiko; Weaver, James C.; Tat, Tracy; Collins, James J.; Ingber, Donald Elliot (Nature Publishing Group, 2014)Current in vitro hematopoiesis models fail to demonstrate the cellular diversity and complex functions of living bone marrow; hence, most translational studies relevant to the hematologic system are conducted in live ... -
Characterization of a Mechanically Tunable Gyroid Photonic Crystal Inspired by the Butterfly Parides Sesostris
Pouya, Caroline; Overvelde, Johannes Tesse bastiaan; Kolle, Mathias; Aizenberg, Joanna; Bertoldi, Katia; Weaver, James C.; Vukusic, Pete (Wiley, 2015)Dynamically tunable three-dimensional photonic materials offer potential for the development of novel optical technologies. For spectral ranges of interest, however, the systematic and high-throughput characterization of ... -
Complex Ordered Patterns in Mechanical Instability Induced Geometrically Frustrated Triangular Cellular Structures
Kang, Sung Hoon; Shan, Sicong; Kosmrlj, Andrej; Noorduin, Wim L.; Shian, Samuel; Weaver, James C.; Clarke, David R.; Bertoldi, Katia (American Physical Society, 2014)Geometrical frustration arises when a local order cannot propagate throughout the space because of geometrical constraints. This phenomenon plays a major role in many systems leading to disordered ground-state configurations. ... -
Condensation on slippery asymmetric bumps
Park, Kyoo-Chul; Kim, Philseok; Grinthal, Alison Elizabeth; He, Neil; Fox, David; Weaver, James C.; Aizenberg, Joanna (Springer Nature, 2016)Controlling dropwise condensation is fundamental to water- harvesting systems1–3, desalination4, thermal power generation4–8, air conditioning9, distillation towers10, and numerous other applications4,5,11. For any of ... -
Dimpled elastic sheets: a new class of non-porous negative Poisson’s ratio materials
Javid, Farhad; Smith-Roberge, Evelyne; Innes, Matthew C.; Shanian, Ali; Weaver, James C.; Bertoldi, Katia (Nature Publishing Group, 2015)In this study, we report a novel periodic material with negative Poisson’s ratio (also called auxetic materials) fabricated by denting spherical dimples in an elastic flat sheet. While previously reported auxetic materials ... -
Fabrication of Paper-Templated Structures of Noble Metals
Christodouleas, Dionysios C.; Simeone, Felice C.; Tayi, Alok Suryavamsee; Targ, Sonia; Weaver, James C.; Jayaram, Kaushik; Fernández-Abedul, Maria Teresa; Whitesides, George McClelland (Wiley-Blackwell, 2017)This manuscript describes a simple and rapid method for fabricating freestanding structures composed primarily (>94% w/w, and 55–80 at%) of noble metals (e.g., gold, silver, platinum, etc.) and having physical morphologies ... -
Gains and losses of coral skeletal porosity changes with ocean acidification acclimation
Fantazzini, Paola; Mengoli, Stefano; Pasquini, Luca; Bortolotti, Villiam; Brizi, Leonardo; Mariani, Manuel; Di Giosia, Matteo; Fermani, Simona; Capaccioni, Bruno; Caroselli, Erik; Prada, Fiorella; Zaccanti, Francesco; Levy, Oren; Dubinsky, Zvy; Kaandorp, Jaap A.; Konglerd, Pirom; Hammel, Jörg U.; Dauphin, Yannicke; Cuif, Jean-Pierre; Weaver, James C.; Fabricius, Katharina E.; Wagermaier, Wolfgang; Fratzl, Peter; Falini, Giuseppe; Goffredo, Stefano (Nature Pub. Group, 2015)Ocean acidification is predicted to impact ecosystems reliant on calcifying organisms, potentially reducing the socioeconomic benefits these habitats provide. Here we investigate the acclimation potential of stony corals ... -
A highly conspicuous mineralized composite photonic architecture in the translucent shell of the blue-rayed limpet
Li, Ling; Kolle, Stefan; Weaver, James C.; Ortiz, Christine; Aizenberg, Joanna; Kolle, Mathias (Nature Pub. Group, 2015)Many species rely on diverse selections of entirely organic photonic structures for the manipulation of light and the display of striking colours. Here we report the discovery of a mineralized hierarchical photonic ... -
Honeycomb Actuators Inspired by the Unfolding of Ice Plant Seed Capsules
Guiducci, Lorenzo; Razghandi, Khashayar; Bertinetti, Luca; Turcaud, Sébastien; Rüggeberg, Markus; Weaver, James C.; Fratzl, Peter; Burgert, Ingo; Dunlop, John W. C. (Public Library of Science, 2016)Plant hydro-actuated systems provide a rich source of inspiration for designing autonomously morphing devices. One such example, the pentagonal ice plant seed capsule, achieves complex mechanical actuation which is critically ... -
Hydrogels with tunable stress relaxation regulate stem cell fate and activity
Chaudhuri, Ovijit; Gu, Luo; Klumpers, Darinka; Darnell, Max; Bencherif, Sidi A.; Weaver, James C.; Huebsch, Nathaniel; Lee, Hong-pyo; Lippens, Evi; Duda, Georg N.; Mooney, David J. (2015)Natural extracellular matrices (ECMs) are viscoelastic and exhibit stress relaxation. However, hydrogels used as synthetic ECMs for three-dimensional (3D) culture are typically elastic. Here, we report a materials approach ... -
Mechanically robust lattices inspired by deep-sea glass sponges
Fernandes, Matheus C.; Aizenberg, Joanna; Weaver, James; Bertoldi, Katia (Springer Science and Business Media LLC, 2020-09-21)The predominantly deep-sea hexactinellid sponges are known for their ability to construct remarkably complex skeletons from amorphous hydrated silica. The skeletal system from one such example, Euplectella aspergillum, ... -
Multi-scale thermal stability of a hard thermoplastic protein-based material
Latza, Victoria; Guerette, Paul A.; Ding, Dawei; Amini, Shahrouz; Kumar, Akshita; Schmidt, Ingo; Keating, Steven; Oxman, Neri; Weaver, James C.; Fratzl, Peter; Miserez, Ali; Masic, Admir (Nature Pub. Group, 2015)Although thermoplastic materials are mostly derived from petro-chemicals, it would be highly desirable, from a sustainability perspective, to produce them instead from renewable biopolymers. Unfortunately, biopolymers ... -
Rational design of reconfigurable prismatic architected materials
Overvelde, Johannes Tesse bastiaan; Weaver, James C.; Hoberman, Chuck; Bertoldi, Katia (Springer Nature, 2017)Advances in fabrication technologies are enabling the production of architected materials with unprecedented properties. Most such materials are characterized by a fixed geometry, but in the design of some materials it is ... -
Self-Replenishing Vascularized Fouling-Release Surfaces
Howell, Caitlin; Vu, Thy L.; Lin, Jennifer; Kolle, Stefan; Juthani, Nidhi; Watson, Emily; Weaver, James C.; Alvarenga, Jack; Aizenberg, Joanna (American Chemical Society (ACS), 2014)Inspired by the long-term effectiveness of living antifouling materials, we have developed a method for the self-replenishment of synthetic biofouling-release surfaces. These surfaces are created by either molding or ... -
Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro
Benam, Kambez H; Villenave, Remi; Lucchesi, Carolina; Varone, Antonio; Hubeau, Cedric; Lee, Hyun-Hee; Alves, Stephen E; Salmon, Michael; Ferrante, Thomas Charles; Weaver, James C.; Bahinski, Anthony; Hamilton, Geraldine A; Ingber, Donald Elliot (Nature Publishing Group, 2015)Here we describe development of a human ‘lung small airway-on-a-chip’ containing a differentiated, mucociliary, bronchiolar epithelium and an underlying microvascular endothelium that experiences fluid flow, which enables ... -
Soft robotic sleeve supports heart function
Roche, Ellen; Horvath, Markus; Wamala, Isaac; Alazmani, Ali; Song, Sang-Eun; Whyte, William; Machaidze, Zurab; Payne, Christopher; Weaver, James C.; Fishbein, Gregory; Kuebler, Joseph D.; V.Vasilyev, Nikolay; Mooney, David; Pigula, Frank Alexander; Walsh, Conor J (American Association for the Advancement of Science (AAAS), 2017-01-18)A soft robotic sleeve modeled on the structure of the human heart assists cardiovascular function in an ex vivo and in vivo porcine model of heart failure. -
Substrate stress relaxation regulates cell spreading
Chaudhuri, Ovijit; Gu, Luo; Darnell, Max Carlton; Klumpers, Darinka; Bencherif, Sidi A.; Weaver, James C.; Huebsch, Nathaniel; Mooney, David J. (Nature Publishing Group, 2015)Studies of cellular mechanotransduction have converged upon the idea that cells sense extracellular matrix (ECM) elasticity by gauging resistance to the traction forces they exert on the ECM. However, these studies typically ... -
A three-dimensional actuated origami-inspired transformable metamaterial with multiple degrees of freedom
Overvelde, Johannes T.B.; de Jong, Twan A.; Shevchenko, Yanina; Becerra, Sergio A.; Whitesides, George M.; Weaver, James C.; Hoberman, Chuck; Bertoldi, Katia (Nature Publishing Group, 2016)Reconfigurable devices, whose shape can be drastically altered, are central to expandable shelters, deployable space structures, reversible encapsulation systems and medical tools and robots. All these applications require ...