Now showing items 1-17 of 17

    • Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses 

      Son, Reuben S.; Smith, Kyle C.; Gowrishankar, Thiruvallur R.; Vernier, P. Thomas; Weaver, James C. (Springer US, 2014)
      Science increasingly involves complex modeling. Here we describe a model for cell electroporation in which membrane properties are dynamically modified by poration. Spatial scales range from cell membrane thickness (5 nm) ...
    • Bone Marrow–on–a–Chip Replicates Hematopoietic Niche Physiology in Vitro 

      Torisawa, Yu-suke; Spina, Catherine; Mammoto, Tadanori; Mammoto, Akiko; Weaver, James C.; Tat, Tracy; Collins, James J.; Ingber, Donald Elliot (Nature Publishing Group, 2014)
      Current in vitro hematopoiesis models fail to demonstrate the cellular diversity and complex functions of living bone marrow; hence, most translational studies relevant to the hematologic system are conducted in live ...
    • Characterization of a Mechanically Tunable Gyroid Photonic Crystal Inspired by the Butterfly Parides Sesostris 

      Pouya, Caroline; Overvelde, Johannes Tesse bastiaan; Kolle, Mathias; Aizenberg, Joanna; Bertoldi, Katia; Weaver, James C.; Vukusic, Pete (Wiley, 2015)
      Dynamically tunable three-dimensional photonic materials offer potential for the development of novel optical technologies. For spectral ranges of interest, however, the systematic and high-throughput characterization of ...
    • Complex Ordered Patterns in Mechanical Instability Induced Geometrically Frustrated Triangular Cellular Structures 

      Kang, Sung Hoon; Shan, Sicong; Kosmrlj, Andrej; Noorduin, Wim L.; Shian, Samuel; Weaver, James C.; Clarke, David R.; Bertoldi, Katia (American Physical Society, 2014)
      Geometrical frustration arises when a local order cannot propagate throughout the space because of geometrical constraints. This phenomenon plays a major role in many systems leading to disordered ground-state configurations. ...
    • Condensation on slippery asymmetric bumps 

      Park, Kyoo-Chul; Kim, Philseok; Grinthal, Alison Elizabeth; He, Neil; Fox, David; Weaver, James C.; Aizenberg, Joanna (Springer Nature, 2016)
      Controlling dropwise condensation is fundamental to water- harvesting systems1–3, desalination4, thermal power generation4–8, air conditioning9, distillation towers10, and numerous other applications4,5,11. For any of ...
    • Dimpled elastic sheets: a new class of non-porous negative Poisson’s ratio materials 

      Javid, Farhad; Smith-Roberge, Evelyne; Innes, Matthew C.; Shanian, Ali; Weaver, James C.; Bertoldi, Katia (Nature Publishing Group, 2015)
      In this study, we report a novel periodic material with negative Poisson’s ratio (also called auxetic materials) fabricated by denting spherical dimples in an elastic flat sheet. While previously reported auxetic materials ...
    • Fabrication of Paper-Templated Structures of Noble Metals 

      Christodouleas, Dionysios C.; Simeone, Felice C.; Tayi, Alok Suryavamsee; Targ, Sonia; Weaver, James C.; Jayaram, Kaushik; Fernández-Abedul, Maria Teresa; Whitesides, George McClelland (Wiley-Blackwell, 2017)
      This manuscript describes a simple and rapid method for fabricating freestanding structures composed primarily (>94% w/w, and 55–80 at%) of noble metals (e.g., gold, silver, platinum, etc.) and having physical morphologies ...
    • Gains and losses of coral skeletal porosity changes with ocean acidification acclimation 

      Fantazzini, Paola; Mengoli, Stefano; Pasquini, Luca; Bortolotti, Villiam; Brizi, Leonardo; Mariani, Manuel; Di Giosia, Matteo; Fermani, Simona; Capaccioni, Bruno; Caroselli, Erik; Prada, Fiorella; Zaccanti, Francesco; Levy, Oren; Dubinsky, Zvy; Kaandorp, Jaap A.; Konglerd, Pirom; Hammel, Jörg U.; Dauphin, Yannicke; Cuif, Jean-Pierre; Weaver, James C.; Fabricius, Katharina E.; Wagermaier, Wolfgang; Fratzl, Peter; Falini, Giuseppe; Goffredo, Stefano (Nature Pub. Group, 2015)
      Ocean acidification is predicted to impact ecosystems reliant on calcifying organisms, potentially reducing the socioeconomic benefits these habitats provide. Here we investigate the acclimation potential of stony corals ...
    • A highly conspicuous mineralized composite photonic architecture in the translucent shell of the blue-rayed limpet 

      Li, Ling; Kolle, Stefan; Weaver, James C.; Ortiz, Christine; Aizenberg, Joanna; Kolle, Mathias (Nature Pub. Group, 2015)
      Many species rely on diverse selections of entirely organic photonic structures for the manipulation of light and the display of striking colours. Here we report the discovery of a mineralized hierarchical photonic ...
    • Honeycomb Actuators Inspired by the Unfolding of Ice Plant Seed Capsules 

      Guiducci, Lorenzo; Razghandi, Khashayar; Bertinetti, Luca; Turcaud, Sébastien; Rüggeberg, Markus; Weaver, James C.; Fratzl, Peter; Burgert, Ingo; Dunlop, John W. C. (Public Library of Science, 2016)
      Plant hydro-actuated systems provide a rich source of inspiration for designing autonomously morphing devices. One such example, the pentagonal ice plant seed capsule, achieves complex mechanical actuation which is critically ...
    • Hydrogels with tunable stress relaxation regulate stem cell fate and activity 

      Chaudhuri, Ovijit; Gu, Luo; Klumpers, Darinka; Darnell, Max; Bencherif, Sidi A.; Weaver, James C.; Huebsch, Nathaniel; Lee, Hong-pyo; Lippens, Evi; Duda, Georg N.; Mooney, David J. (2015)
      Natural extracellular matrices (ECMs) are viscoelastic and exhibit stress relaxation. However, hydrogels used as synthetic ECMs for three-dimensional (3D) culture are typically elastic. Here, we report a materials approach ...
    • Multi-scale thermal stability of a hard thermoplastic protein-based material 

      Latza, Victoria; Guerette, Paul A.; Ding, Dawei; Amini, Shahrouz; Kumar, Akshita; Schmidt, Ingo; Keating, Steven; Oxman, Neri; Weaver, James C.; Fratzl, Peter; Miserez, Ali; Masic, Admir (Nature Pub. Group, 2015)
      Although thermoplastic materials are mostly derived from petro-chemicals, it would be highly desirable, from a sustainability perspective, to produce them instead from renewable biopolymers. Unfortunately, biopolymers ...
    • Rational design of reconfigurable prismatic architected materials 

      Overvelde, Johannes Tesse bastiaan; Weaver, James C.; Hoberman, Chuck; Bertoldi, Katia (Springer Nature, 2017)
      Advances in fabrication technologies are enabling the production of architected materials with unprecedented properties. Most such materials are characterized by a fixed geometry, but in the design of some materials it is ...
    • Self-Replenishing Vascularized Fouling-Release Surfaces 

      Howell, Caitlin; Vu, Thy L.; Lin, Jennifer; Kolle, Stefan; Juthani, Nidhi; Watson, Emily; Weaver, James C.; Alvarenga, Jack; Aizenberg, Joanna (American Chemical Society (ACS), 2014)
      Inspired by the long-term effectiveness of living antifouling materials, we have developed a method for the self-replenishment of synthetic biofouling-release surfaces. These surfaces are created by either molding or ...
    • Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro 

      Benam, Kambez H; Villenave, Remi; Lucchesi, Carolina; Varone, Antonio; Hubeau, Cedric; Lee, Hyun-Hee; Alves, Stephen E; Salmon, Michael; Ferrante, Thomas Charles; Weaver, James C.; Bahinski, Anthony; Hamilton, Geraldine A; Ingber, Donald Elliot (Nature Publishing Group, 2015)
      Here we describe development of a human ‘lung small airway-on-a-chip’ containing a differentiated, mucociliary, bronchiolar epithelium and an underlying microvascular endothelium that experiences fluid flow, which enables ...
    • Substrate stress relaxation regulates cell spreading 

      Chaudhuri, Ovijit; Gu, Luo; Darnell, Max Carlton; Klumpers, Darinka; Bencherif, Sidi A.; Weaver, James C.; Huebsch, Nathaniel; Mooney, David J. (Nature Publishing Group, 2015)
      Studies of cellular mechanotransduction have converged upon the idea that cells sense extracellular matrix (ECM) elasticity by gauging resistance to the traction forces they exert on the ECM. However, these studies typically ...
    • A three-dimensional actuated origami-inspired transformable metamaterial with multiple degrees of freedom 

      Overvelde, Johannes T.B.; de Jong, Twan A.; Shevchenko, Yanina; Becerra, Sergio A.; Whitesides, George M.; Weaver, James C.; Hoberman, Chuck; Bertoldi, Katia (Nature Publishing Group, 2016)
      Reconfigurable devices, whose shape can be drastically altered, are central to expandable shelters, deployable space structures, reversible encapsulation systems and medical tools and robots. All these applications require ...