Browsing by Author "Gilbertson, Mark"
Now showing items 1-7 of 7
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Cavum septum pellucidum in monozygotic twins discordant for combat exposure: relationship to posttraumatic stress disorder
May, Flavia S; Chen, Q.Cece; Gilbertson, Mark; Shenton, Martha Elizabeth; Pitman, roger Keith (Elsevier BV, 2004)Background Abnormally large cavum septum pellucidum has been reported in posttraumatic stress disorder; however, the origin of this association is uncertain. Methods: We utilized magnetic resonance imaging to measure ... -
Clarifying the Origin of Biological Abnormalities in PTSD Through the Study of Identical Twins Discordant for Combat Exposure
Pitman, roger Keith; Gilbertson, Mark; Gurvits, Tamara; May, Flavia S.; Lasko, Natasha B.; Metzger, Linda J; Shenton, Martha Elizabeth; Yehuda, Rachel; Orr, Scott P. (Wiley-Blackwell, 2006)A biological abnormality found to be associated with post-traumatic stress disorder (PTSD) may be, among other things, a pre-trauma vulnerability factor, that is, it may have been present prior to the event’s occurrence ... -
Evidence for Acquired Pregenual Anterior Cingulate Gray Matter Loss from a Twin Study of Combat-Related Posttraumatic Stress Disorder
Kasai, Kiyoto; Yamasue, Hidenori; Gilbertson, Mark Wayne; Shenton, Martha Elizabeth; Rauch, Scott Laurence; Pitman, Roger Keith (Elsevier BV, 2008)Background Controversy exists over the nature and origin of reduced regional brain volumes in posttraumatic stress disorder (PTSD). At issue is whether these reductions represent preexisting vulnerability factors for ... -
Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder
Gurvits, Tamara V.; Shenton, Martha Elizabeth; Hokama, Hiroto; Ohta, Hirokazu; Lasko, Natasha B.; Gilbertson, Mark; Orr, Scott P.; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William; Pitman, roger Keith (Elsevier BV, 1996)This study used quantitative volumetric magnetic resonance imaging techniques to explore the neuroanatomic correlates of chronic, combat-related posttraumatic stress disorder (PTSD) in seven Vietnam veterans with PTSD ... -
The relationship between Hippocampal asymmetry and working memory processing in combat-related PTSD – a monozygotic twin study
Hall, Timothy; Galletly, Cherrie; Clark, C Richard; Veltmeyer, Melinda; Metzger, Linda J; Gilbertson, Mark Wayne; Orr, Scott P.; Pitman, Roger K; McFarlane, Alexander (BioMed Central, 2012)Background: PTSD is associated with reduction in hippocampal volume and abnormalities in hippocampal function. Hippocampal asymmetry has received less attention, but potentially could indicate lateralised differences in ... -
Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma
Gilbertson, Mark; Shenton, Martha Elizabeth; Ciszewski, Aleksandra; Kasai, Kiyoto; Lasko, Natasha B.; Orr, Scott P.; Pitman, roger Keith (Nature Publishing Group, 2002)In animals, exposure to severe stress can damage the hippocampus. Recent human studies show smaller hippocampal volume in individuals with the stress-related psychiatric condition posttraumatic stress disorder (PTSD). Does ... -
Volume of cerebellar vermis in monozygotic twins discordant for combat exposure: Lack of relationship to post-traumatic stress disorder
Levitt, James Jonathan; Chen, Q. Cece; May, Flavia S.; Gilbertson, Mark; Shenton, Martha Elizabeth; Pitman, roger Keith (Elsevier BV, 2006)Several functional neuroimaging studies have implicated the cerebellar vermis in post-traumatic stress disorder (PTSD), but there have been no structural neuroimaging studies of this brain structure in PTSD. We utilized ...