Browsing by Author "Goyal, Raj"
Now showing items 1-6 of 6
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Buried Barrett's Epithelium Following Photodynamic Therapy Shows Reduced Crypt Proliferation and Absence of DNA Content Abnormalities
Hornick, Jason L.; Mino-Kenudson, Mari; Lauwers, Gregory Y.; Liu, Weitian; Goyal, Raj K.; Odze, Robert D. (Springer Nature, 2008)OBJECTIVES: Photodynamic therapy (PDT) is increasingly used for the treatment of patients with Barrett's esophagus (BE) with dysplasia or early carcinoma. Post-PDT, some patients show residual BE either exposed to the ... -
Comparison of DNA Histograms by Standard Flow Cytometry and Image Cytometry on Sections in Barrett's Adenocarcinoma
Huang, Qin; Yu, Chenggong; Zhang, Xiaoqi; Goyal, Raj K. (BioMed Central, 2008)Background: The purpose of this study was to compare DNA histograms obtained by standard flow cytometry (FC) and high fidelity image cytometry on sections (ICS) in normal gastrointestinal mucosa and Barrett's adenocarcinoma ... -
DNA Index Determination with Automated Cellular Imaging System (ACIS) in Barrett's Esophagus: Comparison with CAS 200
Huang, Qin; Yu, Chenggong; Klein, Michael; Fang, James; Goyal, Raj K. (BioMed Central, 2005)Background: For solid tumors, image cytometry has been shown to be more sensitive for diagnosing DNA content abnormalities (aneuploidy) than flow cytometry. Image cytometry has often been performed using the semi-automated ... -
Imaging of Nitric Oxide in Nitrergic Neuromuscular Neurotransmission in the Gut
Thatte, Hemant S.; He, Xue Dao; Goyal, Raj K. (Public Library of Science, 2009)Background: Numerous functional studies have shown that nitrergic neurotransmission plays a central role in peristalsis and sphincter relaxation throughout the gut and impaired nitrergic neurotransmission has been implicated ... -
Myosin Va Plays a Role in Nitrergic Smooth Muscle Relaxation in Gastric Fundus and Corpora Cavernosa of Penis
Chaudhury, Arun; Cristofaro, Vivian; Carew, Josephine A.; Goyal, Raj K.; Sullivan, Maryrose P. (Public Library of Science, 2014)The intracellular motor protein myosin Va is involved in nitrergic neurotransmission possibly by trafficking of neuronal nitric oxide synthase (nNOS) within the nerve terminals. In this study, we examined the role of myosin ... -
Telomerase Inhibition by siRNA Causes Senescence and Apoptosis in Barrett's Adenocarcinoma Cells: Mechanism and Therapeutic Potential
Shammas, Masood A.; Koley, Hemanta; Batchu, Ramesh B.; Bertheau, Robert C.; Protopopov, Alexei; Munshi, Nikhil C; Goyal, Raj K. (BioMed Central, 2005)Background: In cancer cells, telomerase induction helps maintain telomere length and thereby bypasses senescence and provides enhanced replicative potential. Chemical inhibitors of telomerase have been shown to reactivate ...