Browsing by Author "Mizui, Masayuki"

Now showing items 1-2 of 2

    • ICER is requisite for Th17 differentiation 

      Yoshida, Nobuya; Comte, Denis; Mizui, Masayuki; Otomo, Kotaro; Rosetti, Florencia; Mayadas, Tanya N.; Crispín, José C.; Bradley, Sean J.; Koga, Tomohiro; Kono, Michihito; Karampetsou, Maria P.; Kyttaris, Vasileios C.; Tenbrock, Klaus; Tsokos, George C. (Nature Publishing Group, 2016)
      Inducible cAMP early repressor (ICER) has been described as a transcriptional repressor isoform of the cAMP response element modulator (CREM). Here we report that ICER is predominantly expressed in Th17 cells through the ...

    • Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus 

      Wang, Jianxun; Mizui, Masayuki; Zeng, Li-Fan; Bronson, Roderick Terry; Finnell, Michele; Terhorst, Cox; Kyttaris, Vasileios; Tsokos, George C.; Zhang, Zhong-Yin; Kontaridis, Maria Irene (American Society for Clinical Investigation, 2016)
      Systemic lupus erythematosus (SLE) is a devastating multisystemic autoimmune disorder. However, the molecular mechanisms underlying its pathogenesis remain elusive. Some patients with Noonan syndrome, a congenital disorder ...