Now showing items 1-6 of 6

    • GenePattern flow cytometry suite 

      Spidlen, Josef; Barsky, Aaron; Breuer, Karin; Carr, Peter; Nazaire, Marc-Danie; Hill, Barbara Allen; Qian, Yu; Liefeld, Ted; Reich, Michael; Mesirov, Jill; Wilkinson, Peter; Scheuermann, Richard H; Sekaly, Rafick-Pierre; Brinkman, Ryan R (BioMed Central, 2013)
      Background: Traditional flow cytometry data analysis is largely based on interactive and time consuming analysis of series two dimensional representations of up to 20 dimensional data. Recent technological advances have ...
    • Integrated Genomic Analysis of the 8q24 Amplification in Endometrial Cancers Identifies ATAD2 as Essential to MYC-Dependent Cancers 

      Raeder, Maria B.; Birkeland, Even; Trovik, Jone; Krakstad, Camilla; Shehata, Shyemaa; Schumacher, Steven; Zack, Travis Ian; Krohn, Antje; Werner, Henrica MJ.; Moody, Susan E; Wik, Elisabeth; Stefansson, Ingunn M.; Holst, Frederik; Oyan, Anne M.; Tamayo, Pablo; Mesirov, Jill; Kalland, Karl H.; Akslen, Lars A.; Simon, Ronald; Beroukhim, Rameen; Salvesen, Helga B. (Public Library of Science, 2013)
      Chromosome 8q24 is the most commonly amplified region across multiple cancer types, and the typical length of the amplification suggests that it may target additional genes to MYC. To explore the roles of the genes most ...
    • ISMB 2008 Toronto 

      Linial, Michal; Mesirov, Jill; Morrison McKay, B. J.; Rost, Burkhard (Public Library of Science, 2008)
      The International Society for Computational Biology (ISCB) presents the Sixteenth International Conference on Intelligent Systems for Molecular Biology (ISMB 2008), to be held in Toronto, Canada, July 19–23, 2008. Now ...
    • Medulloblastoma Exome Sequencing Uncovers Subtype-Specific Somatic Mutations 

      Pugh, Trevor J.; Weeraratne, Shyamal Dilhan; Archer, Tenley C.; Pomeranz Krummel, Daniel A.; Auclair, Daniel; Bochicchio, James; Carneiro, Mauricio O.; Carter, Scott L.; Cibulskis, Kristian; Erlich, Rachel L.; Greulich, Heidi; Lawrence, Michael S.; Lennon, Niall J.; McKenna, Aaron; Meldrim, James; Ramos, Alex H.; Ross, Michael G.; Russ, Carsten; Shefler, Erica; Sivachenko, Andrey; Sogoloff, Brian; Stojanov, Petar; Tamayo, Pablo; Mesirov, Jill P.; Amani, Vladimir; Teider, Natalia; Sengupta, Soma; Francois, Jessica Pierre; Northcott, Paul A.; Taylor, Michael D.; Yu, Furong; Crabtree, Gerald R.; Kautzman, Amanda G.; Gabriel, Stacey B.; Getz, Gad; Jäger, Natalie; Jones, David T. W.; Lichter, Peter; Pfister, Stefan M.; Roberts, Thomas M.; Meyerson, Matthew; Pomeroy, Scott L.; Cho, Yoon-Jae (2012)
      Medulloblastomas are the most common malignant brain tumors in children1. Identifying and understanding the genetic events that drive these tumors is critical for the development of more effective diagnostic, prognostic ...
    • Portraits of breast cancer progression 

      Dalgin, Gul S; Alexe, Gabriela; Scanfeld, Daniel; Tamayo, Pablo; Mesirov, Jill; Ganesan, Shridar; DeLisi, Charles; Bhanot, Gyan (BioMed Central, 2007)
      Background: Clustering analysis of microarray data is often criticized for giving ambiguous results because of sensitivity to data perturbation or clustering techniques used. In this paper, we describe a new method based ...
    • Transcriptional Profiling of Plasmodium falciparum Parasites from Patients with Severe Malaria Identifies Distinct Low vs. High Parasitemic Clusters 

      Milner, Danny Arnold; Pochet, Nathalie; Krupka, Malkie; Williams, Chris; Seydel, Karl; Taylor, Terrie E.; Van de Peer, Yves; Regev, Aviv; Wirth, Dyann Fergus; Daily, Johanna P.; Mesirov, Jill (Public Library of Science, 2012)
      Background: In the past decade, estimates of malaria infections have dropped from 500 million to 225 million per year; likewise, mortality rates have dropped from 3 million to 791,000 per year. However, approximately 90% ...