Browsing by Author "Reddy, Krishna"
Now showing items 1-4 of 4
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The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells
Pelish, Henry Efrem; Ciesla, William; Tanaka, Nori; Reddy, Krishna Podditur; Shair, Matthew David; Kirchhausen, Tomas Leopold; Lencer, Wayne Isaac (Elsevier BV, 2006)Cyclic AMP- (cAMP) and calcium-dependent agonists stimulate chloride secretion through the coordinated activation of distinct apical and basolateral membrane channels and ion transporters in mucosal epithelial cells. Defects ... -
Rapid urine-based screening for tuberculosis to reduce AIDS-related mortality in hospitalized patients in Africa (the STAMP trial): study protocol for a randomised controlled trial
Gupta-Wright, Ankur; Fielding, Katherine L.; van Oosterhout, Joep J.; Wilson, Douglas K.; Corbett, Elizabeth L.; Flach, Clare; Reddy, Krishna P.; Walensky, Rochelle P.; Peters, Jurgens A.; Alufandika-Moyo, Melanie; Lawn, Stephen D. (BioMed Central, 2016)Background: HIV-associated tuberculosis (TB) co-infection remains an enormous burden to international public health. Post-mortem studies have highlighted the high proportion of HIV-positive adults admitted to hospital with ... -
Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients
Reddy, Krishna P.; Bajwa, Ednan K.; Parker, Robert A.; Onderdonk, Andrew B.; Walensky, Rochelle P. (Oxford University Press, 2016)Among critically ill patients with lower respiratory tract (LRT)-confirmed influenza, we retrospectively observed worse 28-day clinical outcomes in upper respiratory tract (URT)-negative versus URT-positive subjects. This ... -
Using Observational Data to Calibrate Simulation Models
Murray, Eleanor Jane; Robins, James M.; Seage, George R.; Lodi, Sara; Hyle, Emily Parker; Reddy, Krishna Podditur; Freedberg, Kenneth Alan; Hernan, Miguel Angel (SAGE Publications, 2017)BACKGROUND: Individual-level simulation models are valuable tools for comparing the impact of clinical or public health interventions on population health and cost outcomes over time. However, a key challenge is ensuring ...