Browsing by Author "Kim, Wookhyun"
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Cannabinoids Inhibit Insulin Receptor Signaling in Pancreatic \(\beta\)-Cells
Doyle, Máire E.; Liu, Zhuo; Lao, Qizong; Shin, Yu-Kyong; Carlson, Olga D.; Thomas, Sam; Napora, Joshua K.; Moaddel, Ruin; Maudsley, Stuart; Martin, Bronwen; Egan, Josephine M.; Kim, Wookhyun; Kim, Hee Seung; Lee, Eun-Kyung; Wang, Yan; Kulkarni, Rohit Narayan (American Diabetes Association, 2011)Objective: Optimal glucose homeostasis requires exquisitely precise adaptation of the number of insulin-secreting \(\beta\)-cells in the islets of Langerhans. Insulin itself positively regulates \(\beta\)-cell proliferation ... -
In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A
Ham, Hyun Ok; Qu, Zheng; Haller, Carolyn A.; Dorr, Brent M.; Dai, Erbin; Kim, Wookhyun; Liu, David R.; Chaikof, Elliot L. (Nature Publishing Group, 2016)Surface immobilization of bioactive molecules is a central paradigm in the design of implantable devices and biosensors with improved clinical performance capabilities. However, in vivo degradation or denaturation of surface ...