Now showing items 1-2 of 2

    • Cannabinoids Inhibit Insulin Receptor Signaling in Pancreatic \(\beta\)-Cells 

      Doyle, Máire E.; Liu, Zhuo; Lao, Qizong; Shin, Yu-Kyong; Carlson, Olga D.; Thomas, Sam; Napora, Joshua K.; Moaddel, Ruin; Maudsley, Stuart; Martin, Bronwen; Egan, Josephine M.; Kim, Wookhyun; Kim, Hee Seung; Lee, Eun-Kyung; Wang, Yan; Kulkarni, Rohit Narayan (American Diabetes Association, 2011)
      Objective: Optimal glucose homeostasis requires exquisitely precise adaptation of the number of insulin-secreting \(\beta\)-cells in the islets of Langerhans. Insulin itself positively regulates \(\beta\)-cell proliferation ...
    • In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A 

      Ham, Hyun Ok; Qu, Zheng; Haller, Carolyn A.; Dorr, Brent M.; Dai, Erbin; Kim, Wookhyun; Liu, David R.; Chaikof, Elliot L. (Nature Publishing Group, 2016)
      Surface immobilization of bioactive molecules is a central paradigm in the design of implantable devices and biosensors with improved clinical performance capabilities. However, in vivo degradation or denaturation of surface ...