Browsing by Author "Venegas, Jose"

Now showing items 1-5 of 5

    • Allergic Non-Asthmatic Adults Have Regional Pulmonary Responses to Segmental Allergen Challenge 

      Kelly, Vanessa J.; Winkler, Tilo; Venegas, Jose G.; Kone, Mamary; Hamilos, Daniel L.; Afshar, Roshi; Cho, Josalyn L.; Luster, Andrew D.; Medoff, Benjamin D.; Harris, R. Scott (Public Library of Science, 2015)
      Background: Allergic non-asthmatic (ANA) adults experience upper airway symptoms of allergic disease such as rhinorrhea, congestion and sneezing without symptoms of asthma. The aim of this study was to utilize PET-CT ...

    • Deep Inspiration and the Emergence of Ventilation Defects during Bronchoconstriction: A Computational Study 

      Golnabi, Amir H.; Harris, R. Scott; Venegas, Jose G.; Winkler, Tilo (Public Library of Science, 2014)
      Deep inspirations (DIs) have a dilatory effect on airway smooth muscle (ASM) that helps to prevent or reduce more severe bronchoconstriction in healthy individuals. However, this bronchodilation appears to fail in some ...

    • Effects of ventilation strategy on distribution of lung inflammatory cell activity 

      de Prost, Nicolas; Costa, Eduardo L; Wellman, Tyler; Musch, Guido; Tucci, Mauro R; Winkler, Tilo; Harris, R Scott; Venegas, Jose G; Kavanagh, Brian P; Vidal Melo, Marcos F (BioMed Central, 2013)
      Introduction: Leukocyte infiltration is central to the development of acute lung injury, but it is not known how mechanical ventilation strategy alters the distribution or activation of inflammatory cells. We explored how ...

    • Estimation of Noise-Free Variance to Measure Heterogeneity 

      Winkler, Tilo; Melo, Marcos F. Vidal; Degani-Costa, Luiza H.; Harris, R. Scott; Correia, John A.; Musch, Guido; Venegas, Jose G. (Public Library of Science, 2015)
      Variance is a statistical parameter used to characterize heterogeneity or variability in data sets. However, measurements commonly include noise, as random errors superimposed to the actual value, which may substantially ...

    • Ventilation Defect Formation in Healthy and Asthma Subjects Is Determined by Lung Inflation 

      Harris, Robert Scott; Fujii-Rios, Hanae; Winkler, Tilo; Musch, Guido; Vidal Melo, Marcos Francisco; Venegas, Jose Gabriel (Public Library of Science, 2012)
      Background: Imaging studies have demonstrated that ventilation during bronchoconstriction in subjects with asthma is patchy with large ventilation defective areas (Vdefs). Based on a theoretical model, we postulated that ...