Browsing by Author "Gwathmey, Judith Karen"
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[Ca2+]i in Human Heart Failure: A Review and Discussion of Current Areas of Controversy.
Liao, Ronglih; Helm, P. A.; Hajjar, R. J.; Saha, C.; Gwathmey, Judith Karen (Yale Journal of Biology and Medicine, 1994)Multiple abnormalities have been reported in the setting of human heart failure. It is unclear whether detected changes reflect adaptive alterations in myocardium subjected to increased and sustained hemodynamic overload ... -
Chronic Treatment with Carvedilol Improves Ventricular Function and Reduces Myocyte Apoptosis in an Animal Model of Heart Failure
Okafor, Chukwuka C; Perreault-Micale, Cynthia; Hajjar, Roger J; Lebeche, Djamel; Skiroman, Klara; Jabbour, George; Doye, Angelia A; Lee, Michael X.; Laste, Nancy; Gwathmey, Judith Karen (BioMed Central, 2003)Background: \(\beta\)-blocker treatment has emerged as an effective treatment modality for heart failure. Interestingly, \(\beta\)-blockers can activate both pro-apoptotic and anti-apoptotic pathways. Nevertheless, the ...