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    • The Role of Pigmentation and Oncogenic BRAF in Melanoma 

      Mitra, Devarati (2013-02-13)
      BRAF(V600E), the most commonly mutated oncogene in melanoma, is found in about half of patients. By hyperactivating the MAPK pathway, this mutation promotes cell growth and proliferation. Melanocytic BRAF(V600E) alone, ...