Browsing by Author "Mitra, Devarati"
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The Role of Pigmentation and Oncogenic BRAF in Melanoma
Mitra, Devarati (2013-02-13)BRAF(V600E), the most commonly mutated oncogene in melanoma, is found in about half of patients. By hyperactivating the MAPK pathway, this mutation promotes cell growth and proliferation. Melanocytic BRAF(V600E) alone, ...