Now showing items 1-20 of 45

    • Air Pollution Exposures During Adulthood and Risk of Endometriosis in the Nurses’ Health Study II 

      Mahalingaiah, Shruthi; Hart, Jaime E.; Laden, Francine; Aschengrau, Ann; Missmer, Stacey A. (National Institute of Environmental Health Sciences, 2013)
      Background: Particulate matter and proximity to large roadways may promote disease mechanisms, including systemic inflammation, hormonal alteration, and vascular proliferation, that may contribute to the development and ...
    • Ambient ultraviolet radiation exposure and hepatocellular carcinoma incidence in the United States 

      VoPham, Trang Minh; Bertrand, Kimberly Anne; Yuan, Jian-Min; Tamimi, Rulla May; Hart, Jaime Elizabeth; Laden, Francine (Springer Nature, 2017)
      Background: Hepatocellular carcinoma (HCC), the most commonly occurring type of primary liver cancer, has been increasing in incidence worldwide. Vitamin D, acquired from sunlight exposure, diet, and dietary supplements, ...
    • Association between Residences in U.S. Northern Latitudes and Rheumatoid Arthritis: A Spatial Analysis of the Nurses’ Health Study 

      Vieira, Verónica M.; Hart, Jaime Elizabeth; Webster, Thomas F.; Weinberg, Janice; Puett, Robin; Laden, Francine; Costenbader, Karen Harte; Karlson, Elizabeth Wood (National Institute of Environmental Health Sciences, 2010)
      Background: The etiology of rheumatoid arthritis (RA) remains largely unknown, although epidemiologic studies suggest genetic and environmental factors may play a role. Geographic variation in incident RA has been observed ...
    • The association of long-term exposure to PM2.5 on all-cause mortality in the Nurses’ Health Study and the impact of measurement-error correction 

      Hart, Jaime E; Liao, Xiaomei; Hong, Biling; Puett, Robin C; Yanosky, Jeff D; Suh, Helen; Kioumourtzoglou, Marianthi-Anna; Spiegelman, Donna; Laden, Francine (BioMed Central, 2015)
      Background: Long-term exposure to particulate matter less than 2.5 μm in diameter (PM2.5) has been consistently associated with risk of all-cause mortality. The methods used to assess exposure, such as area averages, nearest ...
    • Autism Spectrum Disorder and Particulate Matter Air Pollution before, during, and after Pregnancy: A Nested Case–Control Analysis within the Nurses’ Health Study II Cohort 

      Raz, Raanan; Roberts, Andrea L.; Lyall, Kristen; Hart, Jaime E.; Just, Allan C.; Laden, Francine; Weisskopf, Marc G. (NLM-Export, 2014)
      Background: Autism spectrum disorder (ASD) is a developmental disorder with increasing prevalence worldwide, yet has unclear etiology. Objective: We explored the association between maternal exposure to particulate matter ...
    • Cause-specific mortality in the unionized U.S. trucking industry 

      Laden, Francine; Hart, Jaime Elizabeth; Smith, Thomas J.; Davis, Mary E.; Garshick, Eric (National Institute of Environmental Health Sciences, 2007)
      Background: Occupational and population-based studies have related exposure to fine particulate air pollution, and specifically particulate matter from vehicle exhausts, to cardiovascular diseases and lung cancer. Objectives: ...
    • Chronic Exposure to Fine Particles and Mortality: An Extended Follow-up of the Harvard Six Cities Study from 1974 to 2009 

      Lepeule, Johanna; Laden, Francine; Dockery, Douglas W.; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2012)
      Background: Epidemiologic studies have reported associations between fine particles (aerodynamic diameter ≤ 2.5 µm; PM:2.5) and mortality. However, concerns have been raised regarding the sensitivity of the results to model ...
    • Chronic Fine and Coarse Particulate Exposure, Mortality, and Coronary Heart Disease in the Nurses’ Health Study 

      Puett, Robin C.; Yanosky, Jeff D; Hart, Jaime Elizabeth; Paciorek, Christopher Joseph; Schwartz, Joel David; Suh MacIntosh, Helen H.; Speizer, Frank Erwin; Laden, Francine (National Institute of Environmental Health Sciences, 2009)
      Background: The relationship of fine particulate matter < 2.5 μm in diameter (PM2.5) air pollution with mortality and cardiovascular disease is well established, with more recent long-term studies reporting larger effect ...
    • Chronic Obstructive Pulmonary Disease Mortality in Diesel-Exposed Railroad Workers 

      Hart, Jaime Elizabeth; Laden, Francine; Schenker, Marc B.; Garshick, Eric (National Institute of Environmental Health Sciences, 2006)
      Diesel exhaust is a mixture of combustion gases and ultrafine particles coated with organic compounds. There is concern whether exposure can result in or worsen obstructive airway diseases, but there is only limited ...
    • The Concentration-Response Relation Between PM\(_{2.5}\) and Daily Deaths. 

      Schwartz, Joel David; Laden, Francine; Zanobetti, Antonella (National Institute of Environmental Health Sciences, 2002)
      Particulate air pollution at commonly occurring concentrations is associated with daily deaths. Recent attention has focused on the shape of the concentration-response curve, particularly at low doses. Several recent ...
    • Cox Model Setup: Garshick et al. Respond 

      Garshick, Eric; Laden, Francine; Hart, Jaime Elizabeth; Davis, Mary Elizabeth; Eisen, Ellen A.; Smith, Thomas J. (National Institute of Environmental Health Sciences, 2012)
    • A cross-sectional study of secondhand smoke exposure and respiratory symptoms in non-current smokers in the U.S. trucking industry: SHS exposure and respiratory symptoms 

      Laden, Francine; Chiu, Yueh-Hsiu; Garshick, Eric; Hammond, S Katharine; Hart, Jaime Elizabeth (BioMed Central, 2013)
      Background: Previous studies have suggested associations of adult exposures to secondhand smoke (SHS) with respiratory symptoms, but no study has focused on blue-collar industrial environments. We assessed the association ...
    • Effect Modification of Long‐Term Air Pollution Exposures and the Risk of Incident Cardiovascular Disease in US Women 

      Hart, Jaime E.; Puett, Robin C.; Rexrode, Kathryn M.; Albert, Christine M.; Laden, Francine (John Wiley and Sons Inc., 2015)
      Background: Ambient air pollution exposures have been frequently linked to cardiovascular disease (CVD) morbidity and mortality. However, less is known about the populations most susceptible to these adverse effects. Methods ...
    • The Effect of Dose and Timing of Dose on the Association between Airborne Particles and Survival 

      Schwartz, Joel David; Coull, Brent Andrew; Laden, Francine; Ryan, Louise Marie (2008)
      BACKGROUND: Understanding the shape of the concentration–response curve for particles is important for public health, and lack of such understanding was recently cited by U.S. Environmental Protection Agency (EPA) as a ...
    • Exposure measurement error in PM2.5 health effects studies: A pooled analysis of eight personal exposure validation studies 

      Kioumourtzoglou, Marianthi-Anna; Spiegelman, Donna; Szpiro, Adam A; Sheppard, Lianne; Kaufman, Joel D; Yanosky, Jeff D; Williams, Ronald; Laden, Francine; Hong, Biling; Suh, Helen (BioMed Central, 2014)
      Background: Exposure measurement error is a concern in long-term PM2.5 health studies using ambient concentrations as exposures. We assessed error magnitude by estimating calibration coefficients as the association between ...
    • Exposure to Greenness and Mortality in a Nationwide Prospective Cohort Study of Women 

      James, Peter; Hart, Jaime E.; Banay, Rachel F.; Laden, Francine (National Institute of Environmental Health Sciences, 2016)
      Background: Green, natural environments may ameliorate adverse environmental exposures (e.g., air pollution, noise, and extreme heat), increase physical activity and social engagement, and lower stress. Objectives: We aimed ...
    • Exposure to Traffic Pollution and Increased Risk of Rheumatoid Arthritis 

      Hart, Jaime Elizabeth; Laden, Francine; Puett, Robin C.; Costenbader, Karen Harte; Karlson, Elizabeth Wood (National Institute of Environmental Health Sciences, 2009)
      Background: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease that affects approximately 1% of the adult population, and to date, genetic factors explain < 50% of the risk. Particulate air pollution, ...
    • Factorial validity of an abbreviated Neighborhood Environment Walkability Scale for seniors in the Nurses’ Health Study 

      Starnes, Heather A; McDonough, Meghan H; Tamura, Kosuke; James, Peter; Laden, Francine; Troped, Philip J (BioMed Central, 2014)
      Background: Using validated measures of individuals’ perceptions of their neighborhood built environment is important for accurately estimating effects on physical activity. However, no studies to date have examined the ...
    • Gene expression network analyses in response to air pollution exposures in the trucking industry 

      Chu, Jen-hwa; Hart, Jaime E.; Chhabra, Divya; Garshick, Eric; Raby, Benjamin A.; Laden, Francine (BioMed Central, 2016)
      Background: Exposure to air pollution, including traffic-related pollutants, has been associated with a variety of adverse health outcomes, including increased cardiopulmonary morbidity and mortality, and increased lung ...
    • Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma 

      Cerhan, James R.; Berndt, Sonja I.; Vijai, Joseph; Ghesquières, Hervé; McKay, James; Wang, Sophia S.; Wang, Zhaoming; Yeager, Meredith; Conde, Lucia; de Bakker, Paul; Nieters, Alexandra; Cox, David; Burdett, Laurie; Monnereau, Alain; Flowers, Christopher R.; De Roos, Anneclaire J.; Brooks-Wilson, Angela R.; Lan, Qing; Severi, Gianluca; Melbye, Mads; Gu, Jian; Jackson, Rebecca D.; Kane, Eleanor; Teras, Lauren R.; Purdue, Mark P.; Vajdic, Claire M.; Spinelli, John J.; Giles, Graham G.; Albanes, Demetrius; Kelly, Rachel; Zucca, Mariagrazia; Bertrand, Kimberly Anne; Zeleniuch-Jacquotte, Anne; Lawrence, Charles; Hutchinson, Amy; Zhi, Degui; Habermann, Thomas M.; Link, Brian K.; Novak, Anne J.; Dogan, Ahmet; Asmann, Yan W.; Liebow, Mark; Thompson, Carrie A.; Ansell, Stephen M.; Witzig, Thomas E.; Weiner, George J.; Veron, Amelie S.; Zelenika, Diana; Tilly, Hervé; Haioun, Corinne; Molina, Thierry Jo; Hjalgrim, Henrik; Glimelius, Bengt; Adami, Hans-Olov; Bracci, Paige M.; Riby, Jacques; Smith, Martyn T.; Holly, Elizabeth A.; Cozen, Wendy; Hartge, Patricia; Morton, Lindsay M.; Severson, Richard K.; Tinker, Lesley F.; North, Kari E.; Becker, Nikolaus; Benavente, Yolanda; Boffetta, Paolo; Brennan, Paul; Foretova, Lenka; Maynadie, Marc; Staines, Anthony; Lightfoot, Tracy; Crouch, Simon; Smith, Alex; Roman, Eve; Diver, W. Ryan; Offit, Kenneth; Zelenetz, Andrew; Klein, Robert J.; Villano, Danylo J.; Zheng, Tongzhang; Zhang, Yawei; Holford, Theodore R.; Kricker, Anne; Turner, Jenny; Southey, Melissa C.; Clavel, Jacqueline; Virtamo, Jarmo; Weinstein, Stephanie; Riboli, Elio; Vineis, Paolo; Kaaks, Rudolph; Trichopoulos, Dimitrios; Vermeulen, Roel C. H.; Boeing, Heiner; Tjonneland, Anne; Angelucci, Emanuele; Di Lollo, Simonetta; Rais, Marco; Birmann, Brenda Melanie; Laden, Francine; Giovannucci, Edward L.; Kraft, Phillip L.; Huang, Jinyan; Ma, Baoshan; Ye, Yuanqing; Chiu, Brian C. H.; Sampson, Joshua; Liang, Liming; Park, Ju-Hyun; Chung, Charles C.; Weisenburger, Dennis D.; Chatterjee, Nilanjan; Fraumeni Jr, Joseph F.; Slager, Susan L.; Wu, Xifeng; de Sanjose, Silvia; Smedby, Karin E.; Salles, Gilles; Skibola, Christine F.; Rothman, Nathaniel; Chanock, Stephen J. (Nature Publishing Group, 2014)
      Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma subtype and is clinically aggressive. To identify genetic susceptibility loci for DLBCL, we conducted a meta-analysis of three new genome-wide association ...