Browsing by Title
Now showing items 153-172 of 57135
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A 12-Residue-long Polyleucine Tail Is Sufficient to Anchor Synaptobrevin to the Endoplasmic Reticulum Membrane
(American Society for Biochemistry and Molecular Biology, 1996) -
A 15.65-solar-mass black hole in an eclipsing binary in the nearby spiral galaxy M 33
(Nature Research (part of Springer Nature), 2007)Stellar-mass black holes are found in X-ray-emitting binary systems, where their mass can be determined from the dynamics of their companion stars(1-3). Models of stellar evolution have difficulty producing black holes in ... -
A 200-kb region of human chromosome 22q11.2 confers antipsychotic-responsive behavioral abnormalities in mice
(National Academy of Sciences, 2005) -
A 25 Year Prospective Study of Plasma Adiponectin and Leptin Concentrations and Prostate Cancer Risk and Survival
(American Association for Clinical Chemistry, 2010)BACKGROUND: Adipocytokines may mediate the association between adiposity and lethal prostate cancer outcomes. Methods: In the Physicians' Health Study, we prospectively examined the association of prediagnostic plasma ... -
A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA
(National Academy of Sciences, 2006)A central mystery in the function of site-specific DNA-binding proteins is the detailed mechanism for rapid location and binding of target sites in DNA. Human oxoguanine DNA glycosylase 1 (hOgg1), for example, must search ... -
“‘A Bath of Continuous Sensations’: Warren Brodey’s Quest for Human Augmentation and Intelligent Environments, 1955-1975”
(2018-05-13)This dissertation traces the professional and intellectual development of Warren Brodey (b. 1924). Trained as a psychiatrist and psychoanalyst, Brodey was one of the pioneers of family therapy but eventually abandoned his ... -
A Bayesian Nonparametric Approach to Multi-Task Learning for Contextual Bandits in Mobile Health
(2022-06-03)Reinforcement learning algorithms have found utility in a number of digital interventions, such as in mobile health (mHealth), wherein N users are followed and sequentially treated over T timesteps with the aim of optimizing ... -
A Behavioral Approach to Understanding Leadership Effectiveness
(2020-08-24)Recent research has begun to examine how the effect of leader behaviors differs across subordinates and organizations. Thus far, leadership style has been one of the most discussed and debated factors associated with ... -
A Behavioral Approach to Understanding Leadership Effectiveness
(2020-08-24)Recent research has begun to examine how the effect of leader behaviors differs across subordinates and organizations. Thus far, leadership style has been one of the most discussed and debated factors associated with ... -
A Behavioral Study of Digital Technology for Improving Post-Operative Incentive Spirometer Adherence
(2019-07-25)TITLE: A Behavioral Study of Digital Technology for Improving Post-Operative Incentive Spirometer Adherence Laura Banashek, BA, John Pearson, MD, Charles Safran, MD Purpose: This study seeks to determine whether incentive ... -
A Blood Test for Early Breast Cancer Detection Using Single Molecule Arrays and Machine Learning
(2019-05-24)Early breast cancer diagnosis is challenging due to the high false-positive rate and a lack of molecular classification of the current, imaging-based mammography. An estimated 50% of women screened annually in the U.S. ... -
A Brazilian, a Politician, and a Jew Walk Into a Gay Bar: How the Satirical ‘Fake News’ of the Daily Show With Jon Stewart Adapted Augusto Boal’s Joker System for Its Coverage of LGBTQ Rights
(2018-01-09)This thesis examines modern interpretations of Augusto Boal’s politically engaging and transformative theatrical theory, the Joker System and its derivatives. The concentration of the research uses Boal’s system as the ... -
A broad-spectrum antiviral targeting entry of enveloped viruses
(National Academy of Sciences, 2010)We describe an antiviral small molecule, LJ001, effective against numerous enveloped viruses including Influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1. In sharp ... -
A Broadband, Background-Free Quarter-Wave Plate Based on Plasmonic Metasurfaces
(American Chemical Society, 2012) -
A Bubbling Nearby Molecular Cloud: Complete Shells in Perseus
(American Astronomical Society, 2011)We present a study of the shells (and bubbles) in the Perseus molecular cloud using the COMPLETE survey large-scale (CO)-C-12(1-0) and (CO)-C-13(1-0) maps. The 12 shells reported here are spread throughout most of the ... -
A Business Plan for a Remote Patient Monitoring Startup
(2020-06-24)Purpose: Obstructive sleep apnea (OSA) is a sleep disorder characterized by complete or partial airway closure during sleep. The treatment for OSA is positive airway pressure (PAP), but 34% of patients who are receiving ... -
A Calibrated Defocus Simulator for Research in Passive Ranging
(2022-05-23)Depth from defocus is a prominent area of computer vision research, yet unlike many other areas of the field, there is no dedicated dataset or general library for training and testing depth from defocus applications. As a ... -
A Capitalizing City: Dar Es Salaam and the Emergence of an African Entrepreneurial Elite (C. 1862-2015)
(2018-09-19)A Capitalizing City charts the ways some people of African descent in Dar es Salaam, the commercial and industrial capital of Tanzania, have attempted, historically, to either integrate into the modern capitalist system ... -
A Case Study of Next-Generation Sequencing Operationalization in an Oncology Companion Diagnostic Environment
(2020-03-24)The rise of utilization of next-generation sequencing (NGS) tests in the clinical practice and drug development settings has increased the need for additional regulatory oversight and company practices to support the growth. ... -
a Case Study on the Decision-Making Behind the Development of Linezolid, Daptomycin, and Lysobactin.
(2020-03-02)After the "golden era" of antibiotic discovery in the 1950' and 1960's pharmaceutical companies failed to discover novel antibiotic classes leading them to abandon research in spite of the growing threat of antibiotic ...