Now showing items 1-20 of 26

    • Air Pollution Exposure and Abnormal Glucose Tolerance during Pregnancy: The Project Viva Cohort 

      Fleisch, Abby F.; Gold, Diane R.; Rifas-Shiman, Sheryl L.; Koutrakis, Petros; Schwartz, Joel D.; Kloog, Itai; Melly, Steven; Coull, Brent A.; Zanobetti, Antonella; Gillman, Matthew W.; Oken, Emily (National Institute of Environmental Health Sciences, 2014)
      Background: Exposure to fine particulate matter (PM with diameter ≤ 2.5 μm; PM2.5) has been linked to type 2 diabetes mellitus, but associations with hyperglycemia in pregnancy have not been well studied. Methods: We studied ...
    • Air pollution exposure and gestational diabetes mellitus among pregnant women in Massachusetts: a cohort study 

      Fleisch, Abby F.; Kloog, Itai; Luttmann-Gibson, Heike; Gold, Diane R.; Oken, Emily; Schwartz, Joel D. (BioMed Central, 2016)
      Background: Rodent and human studies suggest an association between air pollution exposure and type 2 diabetes mellitus, but the extent to which air pollution is associated with gestational diabetes mellitus (GDM) is less ...
    • The Association of Early Childhood Cognitive Development and Behavioural Difficulties with Pre-Adolescent Problematic Eating Attitudes 

      Richmond, Rebecca C.; Skugarevsky, Oleg; Yang, Seungmi; Kramer, Michael S.; Wade, Kaitlin H.; Patel, Rita; Bogdanovich, Natalia; Vilchuck, Konstantin; Sergeichick, Natalia; Smith, George Davey; Oken, Emily; Martin, Richard M. (Public Library of Science, 2014)
      Objectives: Few studies have prospectively investigated associations of child cognitive ability and behavioural difficulties with later eating attitudes. We investigated associations of intelligence quotient (IQ), academic ...
    • Association of Prenatal Exposure to Persistent Organic Pollutants with Obesity and Cardiometabolic Traits in Early Childhood: The Rhea Mother–Child Cohort (Crete, Greece) 

      Vafeiadi, Marina; Georgiou, Vaggelis; Chalkiadaki, Georgia; Rantakokko, Panu; Kiviranta, Hannu; Karachaliou, Marianna; Fthenou, Eleni; Venihaki, Maria; Sarri, Katerina; Vassilaki, Maria; Kyrtopoulos, Soterios A.; Oken, Emily; Kogevinas, Manolis; Chatzi, Leda (NLM-Export, 2015)
      Background: Prenatal exposure to endocrine-disrupting chemicals such as persistent organic pollutants (POPs) may increase risk of obesity later in life. Objective: We examined the relation of in utero POPs exposure to ...
    • Associations of cord blood metabolites with early childhood obesity risk 

      Isganaitis, Elvira; Rifas-Shiman, Sheryl L.; Oken, Emily; Dreyfuss, Jonathan; Gall, Walt; Gillman, Matthew W.; Patti, Mary-Elizabeth (2015)
      Background/Objective Rapid postnatal weight gain is a potentially modifiable risk factor for obesity and metabolic syndrome. To identify markers of rapid infancy weight gain and childhood obesity, we analyzed the metabolome ...
    • Balancing the benefits of n-3 polyunsaturated fatty acids and the risks of methylmercury exposure from fish consumption 

      Mahaffey, Kathryn R; Sunderland, Elynor M; Chan, Hing Man; Choi, Anna; Grandjean, Philippe; Mariën, Koenraad; Oken, Emily; Sakamoto, Mineshi; Schoeny, Rita; Weihe, Pál; Yan, Chong-Huai; Yasutake, Akira (Oxford University Press (OUP), 2011)
      Fish and shellfish are widely available foods that provide important nutrients, particularly n-3 polyunsaturated fatty acids (n-3 PUFAs), to many populations globally. These nutrients, especially docosahexaenoic acid, ...
    • Birth weight-for-gestational age is associated with DNA methylation at birth and in childhood 

      Agha, Golareh; Hajj, Hanine; Rifas-Shiman, Sheryl L.; Just, Allan C.; Hivert, Marie-France; Burris, Heather H.; Lin, Xihong; Litonjua, Augusto A.; Oken, Emily; DeMeo, Dawn L.; Gillman, Matthew W.; Baccarelli, Andrea A. (BioMed Central, 2016)
      Background: Both higher and lower fetal growth are associated with cardio-metabolic health later in life, suggesting that prenatal developmental programming determines long-term cardiovascular disease risk. Epigenetic ...
    • Correlations among adiposity measures in school-aged children 

      Boeke, Caroline E; Oken, Emily; Kleinman, Ken P; Rifas-Shiman, Sheryl L; Taveras, Elsie M; Gillman, Matthew W (BioMed Central, 2013)
      Background: Given that it is not feasible to use dual x-ray absorptiometry (DXA) or other reference methods to measure adiposity in all pediatric clinical and research settings, it is important to identify reasonable ...
    • Delivery by caesarean section and risk of obesity in preschool age children: A prospective cohort study 

      Huh, Susanna; Rifas-Shiman, Sheryl Lynn; Zera, Chloe Amelia; Edwards, Janet W. Rich; Oken, Emily; Weiss, Scott Tillman; Gillman, Matthew William (BMJ, 2012)
      Objective: To examine whether delivery by caesarean section is a risk factor for childhood obesity. Design: Prospective pre-birth cohort study (Project Viva). Setting: Eight outpatient multi-specialty practices based ...
    • Early child care and obesity at 12 months of age in the Danish National Birth Cohort 

      Neelon, Sara E Benjamin; Andersen, Camilla Schou; Morgen, Camilla Schmidt; Kamper-Jørgensen, Mads; Oken, Emily; Gillman, Matthew W; Sørensen, Thorkild IA (2014)
      Background/Objectives Evidence suggests that the child care environment may be more obesogenic than the family home, and previous studies have found that child care use may be associated with obesity in children. Few ...
    • Evidence on the Human Health Effects of Low Level Methylmercury Exposure 

      Karagas, Margaret R.; Choi, Anna Lai; Oken, Emily; Horvat, Milena; Schoeny, Rita; Kamai, Elizabeth; Cowell, Whitney J; Grandjean, Philippe; Korrick, Susan Abigail (2012)
      Background: Methylmercury (MeHg) is a known neurotoxicant. Emerging evidence indicates it may have adverse effects on the neurologic and other body systems at common low levels of exposure. Impacts of MeHg exposure could ...
    • Evidence on the Human Health Effects of Low-Level Methylmercury Exposure 

      Karagas, Margaret R.; Choi, Anna Lai; Oken, Emily; Horvat, Milena; Schoeny, Rita; Kamai, Elizabeth; Cowell, Whitney; Grandjean, Philippe; Korrick, Susan Abigail (National Institute of Environmental Health Sciences, 2012)
      Background: Methylmercury (MeHg) is a known neuro-toxicant. Emerging evidence indicates it may have adverse effects on the neurologic and other body systems at common low levels of exposure. Impacts of MeHg exposure could ...
    • Filter Paper Blood Spot Enzyme Linked Immunoassay for Adiponectin and Application in the Evaluation of Determinants of Child Insulin Sensitivity 

      Martin, Richard M.; Patel, Rita; Oken, Emily; Thompson, Jennifer; Zinovik, Alexander; Kramer, Michael S.; Vilchuck, Konstantin; Bogdanovich, Natalia; Sergeichick, Natalia; Foo, Ying; Gusina, Nina (Public Library of Science, 2013)
      Background: Adiponectin is an adipocyte-derived hormone that acts as a marker of insulin sensitivity. Bloodspot sampling by fingerstick onto filter paper may increase the feasibility of large-scale studies of the determinants ...
    • Filter Paper Blood Spot Enzyme Linked Immunoassay for Insulin and Application in the Evaluation of Determinants of Child Insulin Resistance 

      Martin, Richard M.; Patel, Rita; Zinovik, Alexander; Kramer, Michael S.; Oken, Emily; Vilchuck, Konstantin; Bogdanovich, Natalia; Sergeichick, Natalia; Gunnarsson, Robert; Grufman, Lisa; Foo, Ying; Gusina, Nina (Public Library of Science, 2012)
      Background: In large-scale epidemiology, bloodspot sampling by fingerstick onto filter paper has many advantages, including ease and low costs of collection, processing and transport. We describe the development of an ...
    • Growth in Total Height and Its Components and Cardiometabolic Health in Childhood 

      Haugaard, Line Klingen; Baker, Jennifer L.; Perng, Wei; Belfort, Mandy Brown; Rifas-Shiman, Sheryl L.; Switkowski, Karen; Oken, Emily; Gillman, Matthew W. (Public Library of Science, 2016)
      Background: Short stature or short legs is associated with cardiometabolic disease. Few studies have addressed this issue in children, incorporated repeated measures, or studied modern cohorts. Methods: We examined if ...
    • Maternal Fish Consumption, Hair Mercury, and Infant Cognition in a U.S. Cohort 

      Oken, Emily; Wright, Robert O.; Kleinman, Ken Paul; Bellinger, David C.; Amarasiriwardena, Chitra J.; Hu, Howard; Rich-Edwards, Janet Wilson; Gillman, Matthew William (National Institute of Environmental Health Sciences, 2005)
      Fish and other seafood may contain organic mercury but also beneficial nutrients such as n-3 polyunsaturated fatty acids. We endeavored to study whether maternal fish consumption during pregnancy harms or benefits fetal ...
    • Misperceived Pre-pregnancy Body Weight Status Predicts Excessive Gestational Weight Gain: Findings from a US Cohort Study 

      Herring, Sharon J; Oken, Emily; Haines, Jess; Rich-Edwards, Janet Wilson; Rifas-Shiman, Sheryl Lynn; Kleinman, Ken Paul; Gillman, Matthew William (BioMed Central, 2008)
      Background: Excessive gestational weight gain promotes poor maternal and child health outcomes. Weight misperception is associated with weight gain in non-pregnant women, but no data exist during pregnancy. The purpose of ...
    • A Nearly Continuous Measure of Birth Weight for Gestational Age Using a United States National Reference 

      Oken, Emily; Kleinman, Ken Paul; Rich-Edwards, Janet Wilson; Gillman, Matthew William (BioMed Central, 2003)
      Background: Fully understanding the determinants and sequelae of fetal growth requires a continuous measure of birth weight adjusted for gestational age. Published United States reference data, however, provide estimates ...
    • Ongoing Monitoring Of Data Clustering In Multicenter Studies 

      Guthrie, Lauren B.; Oken, Emily; Sterne, Jonathan A.C.; Gillman, Matthew William; Patel, Rita; Vilchuck, Konstantin; Bogdanovich, Natalia; Kramer, Michael S.; Martin, Richard M. (BioMed Central, 2012)
      Background: Multicenter study designs have several advantages, but the possibility of non-random measurement error resulting from procedural differences between the centers is a special concern. While it is possible to ...
    • A pilot randomized controlled trial to promote healthful fish consumption during pregnancy: The Food for Thought Study 

      Oken, Emily; Guthrie, Lauren B; Bloomingdale, Arienne; Platek, Deborah Nehama; Price, Sarah; Haines, Jess; Gillman, Matthew William; Olsen, Sjurdur F.; Bellinger, David C.; Wright, Robert O. (BioMed Central, 2013)
      Background: Nutritionists advise pregnant women to eat fish to obtain adequate docosahexaenoic acid (DHA), an essential nutrient important for optimal brain development. However, concern exists that this advice will lead ...