Browsing by Author "Williams, Paige"

Now showing items 1-20 of 27

    • Association of Blood Lead Levels with Onset of Puberty in Russian Boys 

      Hauser, Russ B.; Sergeyev, Oleg; Korrick, Susan Abigail; Lee, Mary M.; Revich, Boris; Gitin, Elena; Burns, Jane S; Williams, Paige L. (National Institute of Environmental Health Sciences, 2008)
      Background: Epidemiologic studies suggest a temporal trend of earlier onset and longer duration of puberty, raising concerns regarding the potential impact of environmental factors on pubertal development. Lead exposure ...

    • Association of Hexachlorobenzene (HCB), Dichlorodiphenyltrichloroethane (DDT), and Dichlorodiphenyldichloroethylene (DDE) with in Vitro Fertilization (IVF) Outcomes 

      Mahalingaiah, Shruthi; Maity, Arnab; Meeker, John D.; Berry, Katharine; Missmer, Stacey Ann; Williams, Paige L.; Ehrlich, Shelley; Perry, Melissa J.; Cramer, Daniel William; Hauser, Russ B. (National Institute of Environmental Health Sciences, 2012)
      Background: Hexachlorobenzene (HCB), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) are persistent chlorinated pesticides with endocrine activity that may adversely affect the early stages ...

    • Associations of Peripubertal Serum Dioxin and Polychlorinated Biphenyl Concentrations with Pubertal Timing among Russian Boys 

      Burns, Jane S.; Lee, Mary M.; Williams, Paige L.; Korrick, Susan A.; Sergeyev, Oleg; Lam, Thuy; Revich, Boris; Hauser, Russ (National Institute of Environmental Health Sciences, 2016)
      Background: Dioxins, furans, and polychlorinated biphenyls (PCBs), dioxin-like and non-dioxin-like, have been linked to alterations in puberty. Objectives: We examined the association of peripubertal serum levels of these ...

    • Blood Lead Levels and Serum Insulin-Like Growth Factor 1 Concentrations in Peripubertal Boys 

      Fleisch, Abby F.; Burns, Jane S.; Williams, Paige L.; Lee, Mary M.; Sergeyev, Oleg; Korrick, Susan A.; Hauser, Russ (National Institute of Environmental Health Sciences, 2013)
      Background: Childhood lead exposure has been associated with growth delay. However, the association between blood lead levels (BLLs) and insulin-like growth factor 1 (IGF-1) has not been characterized in a large cohort ...

    • CD4 Recovery on Antiretroviral Therapy Is Associated With Decreased Progression to Liver Disease Among Hepatitis C Virus-Infected Injecting Drug Users 

      Anderson, Jeffrey P.; Horsburgh, C. Robert; Williams, Paige L.; Tchetgen Tchetgen, Eric J.; Nunes, David; Cotton, Deborah; Seage, George R. (Oxford University Press, 2015)
      Background. Human immunodeficiency virus (HIV) coinfection accelerates liver disease progression in individuals with chronic hepatitis C. We evaluated the associations of CD4, HIV RNA, and antiretroviral therapy (ART)-induced ...

    • Characterization of Phthalate Exposure among Pregnant Women Assessed by Repeat Air and Urine Samples 

      Adibi, Jennifer J.; Whyatt, Robin M.; Calafat, Antonia M.; Camann, David; Nelson, Heather; Bhat, Hari K.; Perera, Frederica P.; Silva, Manori J.; Williams, Paige L.; Herrick, Robert F.; Hauser, Russ B. (National Institute of Environmental Health Sciences, 2008)
      Background: Although urinary concentrations of phthalate metabolites are frequently used as biomarkers in epidemiologic studies, variability during pregnancy has not been characterized. Methods: We measured phthalate ...

    • Default Mode Connectivity in Youth With Perinatally Acquired HIV 

      Herting, Megan M.; Uban, Kristina A.; Williams, Paige L.; Gautam, Prapti; Huo, Yanling; Malee, Kathleen; Yogev, Ram; Csernansky, John; Wang, Lei; Nichols, Sharon; Van Dyke, Russell; Sowell, Elizabeth R. (Wolters Kluwer Health, 2015)
      Abstract Youth with perinatally acquired human immunodeficiency virus (PHIV+) survive longer with combination antiretroviral therapy, but remain at risk for poor cognitive outcomes. We evaluated whether markers of HIV ...

    • Environmental Exposure to Polychlorinated Biphenyls and p,p´-DDE and Sperm Sex-Chromosome Disomy 

      McAuliffe, Megan E.; Williams, Paige L.; Korrick, Susan Abigail; Altshul, Larisa M.; Perry, Melissa J. (National Institute of Environmental Health Sciences, 2012)
      Background: Chromosomal abnormalities contribute substantially to reproductive problems, but the role of environmental risk factors has received little attention. Objectives: We evaluated the association of polychlorinated ...

    • Evidence of Interaction Between Polychlorinated Biphenyls and Phthalates in Relation to Human Sperm Motility 

      Hauser, Russ B.; Williams, Paige L.; Altshul, Larisa M.; Calafat, Antonia M. (National Institute of Environmental Health Sciences, 2005)
      Previously, we reported evidence of inverse associations between exposure to some polychlorinated biphenyls (PCBs) and some phthalate monoesters in relation to semen parameters, specifically sperm motility. Because humans ...

    • Genetic Modification of the Association between Peripubertal Dioxin Exposure and Pubertal Onset in a Cohort of Russian Boys 

      Humblet, Olivier; Korrick, Susan Abigail; Williams, Paige L.; Sergeyev, Oleg; Emond, Claude; Birnbaum, Linda S.; Burns, Jane S; Altshul, Larisa M.; Patterson, Donald G.; Turner, Wayman E.; Lee, Mary M.; Revich, Boris; Hauser, Russ B. (National Institute of Environmental Health Sciences, 2013)
      Background: Exposure to dioxins has been associated with delayed pubertal onset in both epidemiologic and animal studies. Whether genetic polymorphisms may modify this association is currently unknown. Identifying such ...

    • Genetically determined ancestry is more informative than self-reported race in HIV-infected and -exposed children 

      Spector, Stephen A.; Brummel, Sean S.; Nievergelt, Caroline M.; Maihofer, Adam X.; Singh, Kumud K.; Purswani, Murli U.; Williams, Paige L.; Hazra, Rohan; Van Dyke, Russell; Seage, George R. (Wolters Kluwer Health, 2016)
      Abstract The Pediatric HIV/AIDS Cohort Study (PHACS), the largest ongoing longitudinal study of perinatal HIV-infected (PHIV) and HIV-exposed, uninfected (PHEU) children in the United States, comprises the Surveillance ...

    • Harnessing the Medicaid Analytic eXtract (MAX) to Evaluate Medications in Pregnancy: Design Considerations 

      Palmsten, Kristin; Huybrechts, Krista F.; Mogun, Helen; Kowal, Mary K.; Williams, Paige L.; Michels, Karin B.; Setoguchi, Soko; Hernández-Díaz, Sonia (Public Library of Science, 2013)
      Background: In the absence of clinical trial data, large post-marketing observational studies are essential to evaluate the safety and effectiveness of medications during pregnancy. We identified a cohort of pregnancies ...

    • On the Statistical Properties of Epidemics on Networks 

      Staples, Patrick Christian (2016-05-09)
      One major aim of statistics is to systematically study outcomes of interest in a population by observing the properties of a sample of that population. Some outcomes, such as the total number of people infected in an ...

    • Paternal Urinary Concentrations of Parabens and Other Phenols in Relation to Reproductive Outcomes among Couples from a Fertility Clinic 

      Dodge, Laura E.; Williams, Paige L.; Williams, Michelle A.; Missmer, Stacey A.; Toth, Thomas L.; Calafat, Antonia M.; Hauser, Russ (NLM-Export, 2015)
      Background: Human exposure to phenols, including bisphenol A and parabens, is widespread. Evidence suggests that paternal exposure to environmental chemicals may adversely affect reproductive outcomes. Objectives: We ...

    • Placental biomarkers of phthalate effects on mRNA transcription: application in epidemiologic research 

      Adibi, Jennifer J; Hauser, Russ B.; Williams, Paige L.; Whyatt, Robin M; Thaker, Harshwardhan M; Nelson, Heather; Herrick, Robert F.; Bhat, Hari K (BioMed Central, 2009)
      Background: CYP19 and PPARγ are two genes expressed in the placental trophoblast that are important to placental function and are disrupted by phthalate exposure in other cell types. Measurement of the mRNA of these two ...

    • Predictors of Serum Chlorinated Pesticide Concentrations among Prepubertal Russian Boys 

      Lam, Thuy; Williams, Paige L.; Burns, Jane S.; Sergeyev, Oleg; Korrick, Susan A.; Lee, Mary M.; Birnbaum, Linda S.; Revich, Boris; Altshul, Larisa M.; Patterson, Donald G.; Turner, Wayman E.; Hauser, Russ (National Institute of Environmental Health Sciences, 2013)
      Background: Few studies have evaluated predictors of childhood exposure to organochlorine pesticides (OCPs), a class of lipophilic persistent chemicals. Objectives: Our goal was to identify predictors of serum OCP ...

    • Predictors of serum dioxin levels among adolescent boys in Chapaevsk, Russia: A cross-sectional pilot study 

      Hauser, Russ B.; Williams, Paige L.; Altshul, Larisa M.; Korrick, Susan Abigail; Peeples, Lynne; Patterson, Donald G; Turner, Wayman E; Lee, Mary M; Revich, Boris; Sergeyev, Oleg (BioMed Central, 2005)
      Background: Toxicological studies and limited human studies have demonstrated associations between exposure to polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls ...

    • Predictors of Serum Dioxins and PCBs among Peripubertal Russian Boys 

      Sergeyev, Oleg; Lee, Mary M.; Revich, Boris; Patterson, Donald G.; Turner, Wayman E.; Needham, Larry L.; Saharov, Igor; Burns, Jane S; Williams, Paige L.; Korrick, Susan Abigail; Altshul, Lairsa; Hauser, Russ B. (National Institute of Environmental Health Sciences, 2009)
      Background: Although sources and routes of exposure to dioxins and polychlorinated biphenyls (PCBs) have been studied, information regarding exposure among children is limited. Breast-feeding and diet are two important ...

    • Prepubertal Serum Concentrations of Organochlorine Pesticides and Age at Sexual Maturity in Russian Boys 

      Lam, Thuy; Williams, Paige L.; Lee, Mary M.; Korrick, Susan A.; Birnbaum, Linda S.; Burns, Jane S.; Sergeyev, Oleg; Revich, Boris; Altshul, Larisa M.; Patterson, Donald G.; Hauser, Russ (National Institute of Environmental Health Sciences, 2015)
      Background: Few human studies have evaluated the impact of childhood exposure to organochlorine pesticides (OCP) on pubertal development. Objective: We evaluated associations of serum OCP concentrations [hexachlorobenzene ...

    • Serum Concentrations of Organochlorine Pesticides and Growth among Russian Boys 

      Sergeyev, Oleg; Lee, Mary M.; Revich, Boris; Del Prato, Julie T.; Humblet, Olivier; Patterson, Donald G.; Turner, Wayman E.; Starovoytov, Mikhail; Burns, Jane S; Williams, Paige L.; Korrick, Susan Abigail; Altshul, Larisa M.; Hauser, Russ B. (National Institute of Environmental Health Sciences, 2011)
      Background: Limited human data suggest an association of organochlorine pesticides (OCPs) with adverse effects on children’s growth.: Objective: We evaluated the associations of OCPs with longitudinally assessed growth ...