Browsing by Author "Fregni, Felipe"
Now showing items 21-40 of 44
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The Long-Term Impact of Physical and Emotional Trauma: The Station Nightclub Fire
Schneider, Jeffrey C.; Trinh, Nhi-Ha Thuy; Selleck, Elizabeth; Fregni, Felipe; Salles, Sara S.; Ryan, Colleen M.; Stein, Joel (Public Library of Science, 2012)Background: Survivors of physical and emotional trauma experience enduring occupational, psychological and quality of life impairments. Examining survivors from a large fire provides a unique opportunity to distinguish the ... -
Mental imagery-induced attention modulates pain perception and cortical excitability
Volz, Magdalena Sarah; Suarez-Contreras, Vanessa; Portilla, Andrea L Santos; Fregni, Felipe (BioMed Central, 2015)Background: Mental imagery is a powerful method of altering brain activity and behavioral outcomes, such as performance of cognition and motor skills. Further, attention and distraction can modulate pain-related neuronal ... -
Modulation of Untruthful Responses with Non-Invasive Brain Stimulation
Fecteau, Shirley; Boggio, Paulo; Fregni, Felipe; Pascual-Leone, Alvaro (Frontiers Media S.A., 2013)Deceptive abilities have long been studied in relation to personality traits. More recently, studies explored the neural substrates associated with deceptive skills suggesting a critical role of the prefrontal cortex. Here ... -
Motor Cortex Excitability and BDNF Levels in Chronic Musculoskeletal Pain According to Structural Pathology
Caumo, Wolnei; Deitos, Alícia; Carvalho, Sandra; Leite, Jorge; Carvalho, Fabiana; Dussán-Sarria, Jairo Alberto; Lopes Tarragó, Maria da Graça; Souza, Andressa; Torres, Iraci Lucena da Silva; Fregni, Felipe (Frontiers Media S.A., 2016)The central sensitization syndrome (CSS) encompasses disorders with overlapping symptoms in a structural pathology spectrum ranging from persistent nociception [e.g., osteoarthritis (OA)] to an absence of tissue injuries ... -
Neurobiological Effects of Transcranial Direct Current Stimulation: A Review
Medeiros, Liciane Fernandes; de Souza, Izabel Cristina Custodio; Vidor, Liliane Pinto; de Souza, Andressa; Deitos, Alícia; Volz, Magdalena Sarah; Fregni, Felipe; Caumo, Wolnei; Torres, Iraci L. S. (Frontiers Media S.A., 2012)Transcranial Direct Current Stimulation (tDCS) is a non-invasive brain stimulation technique that is affordable and easy to operate compared to other neuromodulation techniques. Anodal stimulation increases cortical ... -
Neurophysiologic Correlates of Post-stroke Mood and Emotional Control
Doruk, Deniz; Simis, Marcel; Imamura, Marta; Brunoni, André R.; Morales-Quezada, Leon; Anghinah, Renato; Fregni, Felipe; Battistella, Linamara R. (Frontiers Media S.A., 2016)Objective: Emotional disturbance is a common complication of stroke significantly affecting functional recovery and quality of life. Identifying relevant neurophysiologic markers associated with post-stroke emotional ... -
Pharmacological and Combined Interventions for the Acute Depressive Episode: Focus on Efficacy and Tolerability
Brunoni, Andre R; Fraguas, Renerio; Fregni, Felipe (Dove Medical Press, 2009)Background: Use of antidepressants is the gold standard therapy for major depression. However, despite the large number of commercially available antidepressant drugs there are several differences among them in efficacy, ... -
A Phase II, Randomized, Double-Blind, Placebo Controlled, Dose-Response Trial of the Melatonin Effect on the Pain Threshold of Healthy Subjects
Stefani, Luciana Cadore; Muller, Suzana; Torres, Iraci L. S.; Razzolini, Bruna; Rozisky, Joanna R.; Fregni, Felipe; Markus, Regina; Caumo, Wolnei (Public Library of Science, 2013)Background: Previous studies have suggested that melatonin may produce antinociception through peripheral and central mechanisms. Based on the preliminary encouraging results of studies of the effects of melatonin on pain ... -
Placebo Response of Non-Pharmacological and Pharmacological Trials in Major Depression: A Systematic Review and Meta-Analysis
Brunoni, André Russowsky; Lopes, Mariana; Kaptchuk, Ted Jack; Fregni, Felipe (Public Library of Science, 2009)Background: Although meta-analyses have shown that placebo responses are large in Major Depressive Disorder (MDD) trials; the placebo response of devices such as repetitive transcranial magnetic stimulation (rTMS) has not ... -
Processing Nouns and Verbs in the Left Frontal Cortex: A Transcranial Magnetic Stimulation Study
Cappelletti, Marinella; Fregni, Felipe; Shapiro, Kevin; Pascual-Leone, Alvaro; Caramazza, Alfonso (Massachusetts Institute of Technology Press, 2008)Neuropsychological and neurophysiological studies suggest that the production of verbs in speech depends on cortical regions in the left frontal lobe. However, the precise topography of these regions, and their functional ... -
Psychological Sequelae of the Station Nightclub Fire: Comparing Survivors with and without Physical Injuries Using a Mixed-Methods Analysis
Trinh, Nhi-Ha T.; Nadler, Deborah L.; Shie, Vivian; Fregni, Felipe; Gilman, Stephen E.; Ryan, Colleen M.; Schneider, Jeffrey C. (Public Library of Science, 2014)Background: Surveying survivors from a large fire provides an opportunity to explore the impact of emotional trauma on psychological outcomes. Methods: This is a cross-sectional survey of survivors of The Station Fire. ... -
RANDOMIZED CONTROLLED CLINICAL TRIALS IN ORTHOPEDICS: DIFFICULTIES AND LIMITATIONS
Malavolta, Eduardo Angeli; Demange, Marco Kawamura; Gobbi, Riccardo Gomes; Imamura, Marta; Fregni, Felipe (Elsevier, 2011)Randomized controlled clinical trials (RCTs) are considered to be the gold standard for evidence-based medicine nowadays, and are important for directing medical practice through consistent scientific observations. Steps ... -
A Randomized Placebo-Controlled Trial of Targeted Prefrontal Cortex Modulation with Bilateral tDCS in Patients with Crack-Cocaine Dependence
Batista, Edson Kruger; Klauss, Jaisa; Fregni, Felipe; Nitsche, Michael A.; Nakamura-Palacios, Ester Miyuki (Oxford University Press, 2015)Background: Transcranial direct current stimulation over the dorsolateral prefrontal cortex has been shown to be clinically useful in the treatment of drug addiction. Methods: We conducted a double-blind randomized clinical ... -
Simultaneous EEG Monitoring During Transcranial Direct Current Stimulation
Schestatsky, Pedro; Morales-Quezada, Leon; Fregni, Felipe (MyJove Corporation, 2013)Transcranial direct current stimulation (tDCS) is a technique that delivers weak electric currents through the scalp. This constant electric current induces shifts in neuronal membrane excitability, resulting in secondary ... -
Spared Primary Motor Cortex and The Presence of MEP in Cerebral Palsy Dictate the Responsiveness to tDCS during Gait Training
Grecco, Luanda A. Collange; Oliveira, Claudia Santos; Galli, Manuela; Cosmo, Camila; Duarte, Natália de Almeida Carvalho; Zanon, Nelci; Edwards, Dylan J.; Fregni, Felipe (Frontiers Media S.A., 2016)The current priority of investigations involving transcranial direct current stimulation (tDCS) and neurorehabilitation is to identify biomarkers associated with the positive results of the interventions such that respondent ... -
Systematic Review of Parameters of Stimulation, Clinical Trial Design Characteristics, and Motor Outcomes in Non-Invasive Brain Stimulation in Stroke
Adeyemo, Bamidele Oyebamiji; Simis, Marcel; Macea, Debora Duarte; Fregni, Felipe (Frontiers Media S.A., 2012)Introduction/Objectives: Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation are two powerful non-invasive neuromodulatory therapies that have the potential to alter and evaluate ... -
tDCS and Robotics on Upper Limb Stroke Rehabilitation: Effect Modification by Stroke Duration and Type of Stroke
Straudi, Sofia; Fregni, Felipe; Martinuzzi, Carlotta; Pavarelli, Claudia; Salvioli, Stefano; Basaglia, Nino (Hindawi Publishing Corporation, 2016)Objective:. The aim of this exploratory pilot study is to test the effects of bilateral tDCS combined with upper extremity robot-assisted therapy (RAT) on stroke survivors. Methods. We enrolled 23 subjects who were allocated ... -
Technique and Considerations in the Use of 4x1 Ring High-definition Transcranial Direct Current Stimulation (HD-tDCS)
Villamar, Mauricio F.; Volz, Magdalena Sarah; Bikson, Marom; Datta, Abhishek; DaSilva, Alexandre F.; Fregni, Felipe (MyJove Corporation, 2013)High-definition transcranial direct current stimulation (HD-tDCS) has recently been developed as a noninvasive brain stimulation approach that increases the accuracy of current delivery to the brain by using arrays of ... -
Temporal Lobe Cortical Electrical Stimulation during the Encoding and Retrieval Phase Reduces False Memories
Boggio, Paulo S.; Fregni, Felipe; Valasek, Claudia; Ellwood, Sophie; Chi, Richard Po-Hung; Gallate, Jason; Pascual-Leone, Alvaro; Snyder, Allan (Public Library of Science, 2009)A recent study found that false memories were reduced by 36% when low frequency repetitive transcranial magnetic stimulation (rTMS) was applied to the left anterior temporal lobe after the encoding (study) phase. Here we ... -
Transcranial Direct Current Stimulation Combined with Aerobic Exercise to Optimize Analgesic Responses in Fibromyalgia: A Randomized Placebo-Controlled Clinical Trial
Mendonca, Mariana E.; Simis, Marcel; Grecco, Luanda C.; Battistella, Linamara R.; Baptista, Abrahão F.; Fregni, Felipe (Frontiers Media S.A., 2016)Fibromyalgia is a chronic pain syndrome that is associated with maladaptive plasticity in neural central circuits. One of the neural circuits that are involved in pain in fibromyalgia is the primary motor cortex. We tested ...