Now showing items 21-40 of 68

    • Dichotic listening in schizotypal personality disorder: Evidence for gender and laterality effects 

      Voglmaier, Martina M.; Seidman, Larry Joel; Niznikiewicz, Margaret A.; Madan, Anita; Dickey, Chandlee C.; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2009)
      Verbal dichotic listening performance was examined in 42 right-handed men and women with DSM-IV-defined schizotypal personality disorder (SPD) and 68 right-handed controls. As expected, both male and female control groups ...
    • Diffusion tractography of the fornix in schizophrenia 

      Fitzsimmons, Jennifer J; Kubicki, Marek R.; Smith, K.; Bushell, G.; Estepar, R. San Jose; Westin, Carl-Fredrik; Nestor, Paul Gerard; Niznikiewicz, Margaret A.; Kikinis, Ron; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2009)
      Background: White matter fiber tracts, especially those interconnecting the frontal and temporal lobes, are likely implicated in pathophysiology of schizophrenia. Very few studies, however, have focused on the fornix, a ...
    • Disruption of function–structure coupling in brain regions sub-serving self monitoring in schizophrenia 

      Araki, Tsuyoshi; Niznikiewicz, Margaret A.; Kawashima, Toshiro; Nestor, Paul Gerard; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2013)
      Deficits in self monitoring are a core feature of cognitive dysfunction in schizophrenia, and may be the basis for disturbances of self and lack of insight, ultimately impacting social functioning. However, the functional ...
    • Dissociable contributions of MRI volume reductions of superior temporal and fusiform gyri to symptoms and neuropsychology in schizophrenia 

      Nestor, Paul Gerard; Onitsuka, Toshiaki; Gurrera, Ronald Joseph; Niznikiewicz, Margaret A.; Frumin, Melissa; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2007)
      We sought to identify the functional correlates of reduced magnetic resonance imaging (MRI) volumes of the superior temporal gyrus (STG) and the fusiform gyrus (FG) in patients with chronic schizophrenia. MRI volumes, ...
    • DTI and MTR abnormalities in schizophrenia: Analysis of white matter integrity 

      Kubicki, Marek R.; Park, H.; Westin, Carl-Fredrik; Nestor, Paul Gerard; Mulkern, Robert Vincent; Maier, Stephan Ernst; Niznikiewicz, Margaret A.; Connor, E.E.; Levitt, James Jonathan; Frumin, Melissa; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2005)
      Diffusion tensor imaging (DTI) studies in schizophrenia demonstrate lower anisotropic diffusion within white matter due either to loss of coherence of white matter fiber tracts, to changes in the number and/or density of ...
    • Early nicotine withdrawal and transdermal nicotine effects on neurocognitive performance in schizophrenia 

      Ahnallen, Christopher G; Nestor, Paul Gerard; Shenton, Martha Elizabeth; McCarley, Robert William; Niznikiewicz, Margaret A. (Elsevier BV, 2008)
      As cigarette smoking prevalence rates approach 90% in schizophrenia, an important emerging question is the role of nicotine in the disease-related disturbance in cognition. We therefore tested a total of 38 male cigarette ...
    • Electrophysiological Correlates of Language Processing in Schizotypal Personality Disorder 

      Niznikiewicz, Margaret A.; Voglmaier, Martina M.; Shenton, Martha Elizabeth; Seidman, Larry Joel; Dickey, Chandlee C.; Rhoads, Richard; Teh, Enkeat; McCarley, Robert William (American Psychiatric Publishing, 1999)
      Objective: This study examined whether the electrophysiological correlates of language processing found previously to be abnormal in schizophrenia are also abnormal in schizotypal individuals. The authors used the N400 ...
    • Emotional Cues during Simultaneous Face and Voice Processing: Electrophysiological Insights 

      Liu, Taosheng; Pinheiro, Ana; Zhao, Zhongxin; Nestor, Paul Gerard; McCarley, Robert William; Niznikiewicz, Margaret A. (Public Library of Science, 2012)
      Both facial expression and tone of voice represent key signals of emotional communication but their brain processing correlates remain unclear. Accordingly, we constructed a novel implicit emotion recognition task consisting ...
    • Facial emotion recognition and facial affect display in schizotypal personality disorder 

      Dickey, Chandlee C.; Panych, Lawrence Patrick; Voglmaier, Martina M.; Niznikiewicz, Margaret A.; Terry, Douglas P.; Murphy, Cara; Zacks, Rayna; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2011)
      Background—Patients with schizophrenia have deficits in facial affect expression and detection that hinder social interactions. The goal of this study was to examine whether or not epidemiologically-related antipsychotic-naïve ...
    • Factors in sensory processing of prosody in schizotypal personality disorder: An fMRI experiment 

      Dickey, Chandlee C.; Morocz, Istvan; Minney, Daniel; Niznikiewicz, Margaret A.; Voglmaier, Martina M.; Panych, Lawrence Patrick; Khan, Usman; Zacks, Rayna; Terry, Douglas P.; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2010)
      Introduction—Persons diagnosed with schizophrenia demonstrate deficits in prosody recognition. To examine prosody along the schizophrenia spectrum, antipsychotic-naïve schizotypal personality disorder (SPD) subjects and ...
    • Fiber geometry in the corpus callosum in schizophrenia: Evidence for transcallosal misconnection 

      Whitford, Thomas; Savadjiev, Peter; Kubicki, Marek R.; O, Lauren J.; Terry, Douglas P.; Bouix, Sylvain; Westin, Carl-Fredrik; Schneiderman, Jason S.; Bobrow, Laurel; Rausch, Andrew C.; Niznikiewicz, Margaret A.; Nestor, Paul Gerard; Pantelis, Christos; Wood, Stephen J.; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2011)
      Background—Structural abnormalities in the callosal fibers connecting the heteromodal association areas of the prefrontal and temporoparietal cortices bilaterally have been suggested to play a role in the etiology of ...
    • The five-factor model in schizotypal personality disorder 

      Gurrera, Ronald Joseph; Dickey, Chandlee C.; Niznikiewicz, Margaret A.; Voglmaier, Martina M.; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2005)
      Studies of the five-factor model of personality in schizotypal personality disorder (SPD) have produced inconsistent results, particularly with respect to openness. In the present study, the NEO-FFI was used to measure ...
    • Fornix Integrity and Hippocampal Volume in Male Schizophrenic Patients 

      Kuroki, Noriomi; Kubicki, Marek R.; Nestor, Paul Gerard; Salisbury, Dean F.; Park, Hae-Jeong; Levitt, James Jonathan; Woolston, Sophie; Frumin, Melissa; Niznikiewicz, Margaret A.; Westin, Carl-Fredrik; Maier, Stephan Ernst; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2006)
      Background: The hippocampus has been shown to be abnormal in schizophrenia. The fornix is one of the main fiber tracts connecting the hippocampus with other brain regions. Few studies have evaluated the fornix in schizophrenia, ...
    • From Semantics to Feelings: How Do Individuals with Schizophrenia Rate the Emotional Valence of Words? 

      Pinheiro, Ana; McCarley, Robert William; Thompson, Elizabeth C.; Gonçalves, Óscar F.; Niznikiewicz, Margaret A. (Hindawi Publishing Corporation, 2012)
      Schizophrenia is characterized by both emotional and language abnormalities. However, in spite of reports of preserved evaluation of valence of affective stimuli, such as pictures, it is less clear how individuals with ...
    • Fronto–Temporal Disconnectivity in Schizotypal Personality Disorder: A Diffusion Tensor Imaging Study 

      Nakamura, Motoaki; McCarley, Robert William; Kubicki, Marek R.; Dickey, Chandlee C.; Niznikiewicz, Margaret A.; Voglmaier, Martina M.; Seidman, Larry Joel; Maier, Stephan Ernst; Westin, Carl-Fredrik; Kikinis, Ron; Shenton, Martha Elizabeth (Elsevier BV, 2005)
      Background: Using diffusion tensor imaging (DTI), we previously reported abnormalities in two critical white matter tracts in schizophrenia, the uncinate fasciculus (UF) and the cingulum bundle (CB), both related to ...
    • Functional and Structural Deficits in Brain Regions Subserving Face Perception in Schizophrenia 

      Onitsuka, Toshiaki; Niznikiewicz, Margaret A.; Spencer, Kevin M.; Frumin, Melissa; Kuroki, Noriomi; Lucia, Lisa C.; Shenton, Martha Elizabeth; McCarley, Robert William (American Psychiatric Publishing, 2006)
      Objective: Schizophrenia impairs many cognitive functions, including face perception. Veridical face perception is critical for social interaction, including distinguishing friend from foe and familiar from unfamiliar ...
    • Gray matter volume reduction in rostral middle frontal gyrus in patients with chronic schizophrenia 

      Kikinis, Zora; Fallon, J.H.; Niznikiewicz, Margaret A.; Nestor, Paul Gerard; Davidson, C.; Bobrow, L.; Pelavin, P.E.; Fischl, Bruce R.; Yendiki, Anastasia; McCarley, Robert William; Kikinis, Ron; Kubicki, Marek R.; Shenton, Martha Elizabeth (Elsevier BV, 2010)
      The dorsolateral prefrontal cortex (DLPFC) is a brain region that has figured prominently in studies of schizophrenia and working memory, yet the exact neuroanatomical localization of this brain region remains to be defined. ...
    • Identification of neural circuits underlying P300 abnormalities in schizophrenia 

      O'Donnell, Brian F.; McCarley, Robert William; Potts, Geoffrey F.; Salisbury, Dean F.; Nestor, Paul Gerard; Hirayasu, Yoshio; Niznikiewicz, Margaret A.; Barnard, John; Jen Shen, Zi; Weinstein, David M.; Bookstein, Fred L.; Shenton, Martha Elizabeth (Wiley-Blackwell, 1999)
      Event-related potentials (ERPs) provide a noninvasive method to evaluate neural activation and cognitive processes in schizophrenia. The pathophysiological significance of these findings would be greatly enhanced if ...
    • Increased diffusivity in superior temporal gyrus in patients with schizophrenia: A Diffusion Tensor Imaging study 

      Lee, KangUk; Yoshida, Takeshi; Kubicki, Marek R.; Bouix, Sylvain; Westin, Carl-Fredrik; Kindlmann, Gordon; Niznikiewicz, Margaret A.; Cohen, Adam Brian; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2009)
      Background: Superior temporal gyrus (STG) volume reduction is one of the most consistent findings in schizophrenia. The goal of this study was to conduct the first diffusion tensor imaging (DTI) study to investigate altered ...
    • Large CSF Volume Not Attributable to Ventricular Volume in Schizotypal Personality Disorder 

      Dickey, Chandlee C.; Shenton, Martha Elizabeth; Hirayasu, Yoshio; Fischer, Iris; Voglmaier, Martina M.; Niznikiewicz, Margaret A.; Seidman, Larry Joel; Fraone, Stephanie; McCarley, Robert William (American Psychiatric Publishing, 2000)
      Objective: The purpose of this study was to determine whether schizotypal personality disorder, which has the same genetic diathesis as schizophrenia, manifests abnormalities in whole-brain and CSF volumes. Method: Sixteen ...