Now showing items 21-40 of 212

    • Cell Encapsulation in Sub-mm Sized Gel Modules Using Replica Molding 

      McGuigan, Alison P.; Bruzewicz, Derek A.; Glavan, Ana; Butte, Manish; Whitesides, George (Public Library of Science, 2008)
      For many types of cells, behavior in two-dimensional (2D) culture differs from that in three-dimensional (3D) culture. Among biologists, 2D culture on treated plastic surfaces is currently the most popular method for cell ...
    • Characterizing the Metal–SAM Interface in Tunneling Junctions 

      Bowers, Carleen Morris; Liao, Kung-ching; Zaba, Tomasz; Rappoport, Dmitrij; Baghbanzadeh, Mostafa; Breiten, Benjamin; Krzykawska, Anna; Cyganik, Piotr; Whitesides, George McClelland (American Chemical Society (ACS), 2015)
      his paper investigates the influence of the interface between a gold or silver metal electrode and an n-alkyl SAM (supported on that electrode) on the rate of charge transport across junctions with structure Met(Au or ...
    • Charge Transport Across Insulating Self-Assembled Monolayers: Non-equilibrium Approaches and Modeling To Relate Current and Molecular Structure 

      Mirjani, Fatemeh; Thijssen, Joseph M.; Whitesides, George McClelland; Ratner, Mark A. (American Chemical Society (ACS), 2014)
      This paper examines charge transport by tunneling across a series of electrically insulating molecules with the structure HS(CH2)4CONH(CH2)2R) in the form of self-assembled monolayers (SAMs), supported on silver. The ...
    • Charge Transport and Rectification in Arrays of SAM-Based Tunneling Junctions 

      Nijhuis, Christian A.; Reus, William F.; Barber, Jabulani Randall; Dickey, Michael D.; Whitesides, George M. (American Chemical Society, 2010)
      This paper describes a method of fabrication that generates small arrays of tunneling junctions based on self-assembled monolayers (SAMs); these junctions have liquid-metal top-electrodes stabilized in microchannels and ...
    • Charge Tunneling along Short Oligoglycine Chains 

      Baghbanzadeh, Mostafa; Bowers, Carleen Morris; Rappoport, Dmitrij; Zaba, Tomasz; Gonidec, Mathieu; Al-Sayah, Mohammad; Cyganik, Piotr; Aspuru-Guzik, Alan; Whitesides, George McClelland (Wiley-Blackwell, 2015)
      This work examines charge transport (CT) through self-assembled monolayers (SAMs) of oligoglycines having an N-terminal cysteine group that anchors the molecule to a gold substrate, and demonstrate that CT is rapid (relative ...
    • Charging of Multiple Interacting Particles by Contact Electrification 

      Soh, Siowling; Liu, Helena; Cademartiri, Rebecca; Yoon, Hyo Jae; Whitesides, George McClelland (American Chemical Society (ACS), 2014)
      Many processes involve the movement of a disordered collection of small particles (e.g., powders, grain, dust, and granular foods). These particles move chaotically, interact randomly among themselves, and gain electrical ...
    • Chemical Approaches to the Surface Engineering of Paper and Cellulose-Based Materials for Microfluidics, Electronics and Low-Cost Diagnostics 

      Glavan, Ana (2016-01-27)
      Paper (and other cellulose-based materials such as cotton thread and fabrics) are underexploited as materials for the construction of “high-tech” and “lab-on-a-chip” devices. One major drawback of paper is its tendency to ...
    • Chemistry and the Worm: Caenorhabditis elegans as a Platform for Integrating Chemical and Biological Research 

      Hulme, S. Elizabeth; Whitesides, George McClelland (Wiley-Blackwell, 2011)
      This Review discusses the potential usefulness of the worm Caenorhabditis elegans as a model organism for chemists interested in studying living systems. C. elegans, a 1 mm long roundworm, is a popular model organism in ...
    • Coated and uncoated cellophane as materials for microplates and open-channel microfluidics devices 

      Hamedi, Mahiar; Unal, Baris; Kerr, Emily Faye; Glavan, Ana C.; Fernandez-Abedul, M. Teresa; Whitesides, George McClelland (Royal Society of Chemistry (RSC), 2016)
      This communication describes the use of uncoated cellophane (regenerated cellulose films) for the fabrication of microplates, and the use of coated cellophane for the fabrication of open-channel microfluidic devices. The ...
    • Cofabrication: A Strategy for Building Multicomponent Microsystems 

      Siegel, Adam C.; Tang, Sindy K. Y.; Nijhuis, Christian A.; Hashimoto, Michinao; Phillips, Scott T.; Dickey, Michael D.; Whitesides, George McClelland (American Chemical Society (ACS), 2010)
      This Account describes a strategy for fabricating multicomponent microsystems in which the structures of essentially all of the components are formed in a single step of micromolding. This strategy, which we call ...
    • Combining Step Gradients and Linear Gradients in Density 

      Kumar, Ashok Ashwin; Walz, Jenna A.; Gonidec, Mathieu; Mace, Charles R.; Whitesides, George McClelland (American Chemical Society (ACS), 2015)
      Combining aqueous multiphase systems (AMPS) and magnetic levitation (MagLev) provides a method to produce hybrid gradients in apparent density. AMPS—solutions of different polymers, salts, or surfactants that spontaneously ...
    • Comparison of SAM-Based Junctions with Ga2O3/EGaIn Top Electrodes to Other Large-Area Tunneling Junctions 

      Nijhuis, Christian A.; Reus, William F.; Barber, Jabulani Randall; Whitesides, George M. (American Chemical Society, 2012)
      This paper compares the J(V) characteristics obtained for self-assembled monolayer (SAM)-based tunneling junctions with top electrodes of the liquid eutectic of gallium and indium (EGaIn) fabricated using two different ...
    • Complexes of Native Ubiquitin and Dodecyl Sulfate Illustrate the Nature of Hydrophobic and Electrostatic Interactions in the Binding of Proteins and Surfactants 

      Shaw, Bryan F.; Schneider, Grégory F.; Arthanari, Haribabu; Narovlyansky, Max; Moustakas, Demetri; Durazo, Armando; Wagner, Gerhard; Whitesides, George McClelland (American Chemical Society (ACS), 2011)
      A previous study, using capillary electrophoresis (CE) [J. Am. Chem. Soc.2008, 130, 17384–17393], reported that six discrete complexes of ubiquitin (UBI) and sodium dodecyl sulfate (SDS) form at different concentrations ...
    • Contact De-electrification of Electrostatically Charged Polymers 

      Soh, Siowling; Kwok, Sen Wai; Liu, Helena; Whitesides, George M. (American Chemical Society, 2012)
      The contact electrification of insulating organic polymers is still incompletely understood, in part because multiple fundamental mechanisms may contribute to the movement of charge. This study describes a mechanism ...
    • Continuously tunable microdroplet-laser in a microfluidic channel 

      Tang, Sindy K. Y.; Derda, Ratmir; Quan, Qimin; Loncar, Marko; Whitesides, George McClelland (Optical Society of America (OSA), 2011)
      This paper describes the generation and optical characterization of a series of dye-doped droplet-based optical microcavities with continuously decreasing radius in a microfluidic channel. A flow-focusing nozzle generated ...
    • Control of soft machines using actuators operated by a Braille display 

      Mosadegh, Bobak; Mazzeo, Aaron D.; Shepherd, Robert F.; Morin, Stephen A.; Gupta, Unmukt; Sani, Idin Zhalehdoust; Lai, David; Takayama, Shuichi; Whitesides, George McClelland (Royal Society of Chemistry (RSC), 2014)
      One strategy for actuating soft machines (e.g., tentacles, grippers, and simple walkers) uses pneumatic inflation of networks of small channels in an elastomeric material. Although the management of a few pneumatic inputs ...
    • Control over Rectification in Supramolecular Tunneling Junctions 

      Wimbush, Kim S.; Reus, William F.; van der Wiel, Wilfred G.; Reinhoudt, David N.; Whitesides, George McClelland; Nijhuis, Christian A.; Velders, Aldrik H. (Wiley-Blackwell, 2010)
    • The Core Apoptotic Executioner Proteins CED-3 and CED-4 Promote Initiation of Neuronal Regeneration in Caenorhabditis elegans 

      Pinan-Lucarre, Berangere; Gabel, Christopher V.; Reina, Christopher P.; Hulme, S. Elizabeth; Shevkoplyas, Sergey S.; Slone, R. Daniel; Xue, Jian; Qiao, Yujie; Weisberg, Sarah; Roodhouse, Kevin; Whitesides, George M.; Samuel, Aravinthan DT; Driscoll, Monica (Public Library of Science, 2012)
      A critical accomplishment in the rapidly developing field of regenerative medicine will be the ability to foster repair of neurons severed by injury, disease, or microsurgery. In C. elegans, individual visualized axons ...
    • The Core Apoptotic Executioner Proteins CED-3 and CED-4 Promote Neuronal Regeneration in Caenorhabditis Elegans 

      Pinan-Lucarre, Berangere; Gabel, Christopher V.; Reina, Christopher P.; Hulme, S. Elizabeth; Shevkopylas, Sergey S.; Slone, R. Daniel; Xue, Jian; Qiao, Yujie; Weisberg, Sarah; Roodhouse, Kevin; Sun, Lin; Whitesides, George M.; Samuel, Aravinthan DT; Drisocll, Monica (Public Library of Science, 2012)
      A critical accomplishment in the rapidly developing field of regenerative medicine will be the ability to foster repair of neurons severed by injury, disease, or microsurgery. In C. elegans, individual visualized axons can ...
    • Deep Sequencing Analysis of Phage Libraries using Illumina Platform 

      Matochko, Wadim L.; Chu, Kiki; Jin, Bingjie; Lee, Sam Whan; Whitesides, George McClelland; Derda, Ratmir (Elsevier BV, 2012)
      This paper presents an analysis of phage-displayed libraries of peptides using Illumina. We describe steps for the preparation of short DNA fragments for deep sequencing and MatLab software for the analysis of the results. ...