Browsing by Author "Loda, Massimo"

Now showing items 21-25 of 25

    • Serum Lipid Profiles and Cancer Risk in the Context of Obesity: Four Meta-Analyses 

      Melvin, Jennifer C.; Holmberg, Lars; Rohrmann, Sabine; Loda, Massimo; Van Hemelrijck, Mieke (Hindawi Publishing Corporation, 2013)
      The objective here was to summarize the evidence for, and quantify the link between, serum markers of lipid metabolism and risk of obesity-related cancers. PubMed and Embase were searched using predefined inclusion criteria ...

    • A Synthetic Form of Frizzled 8-Associated Antiproliferative Factor Enhances p53 Stability through USP2a and MDM2 

      Kim, Jayoung; Keay, Susan K.; You, Sungyong; Loda, Massimo; Freeman, Michael R. (Public Library of Science, 2012)
      Frizzled 8-associated Antiproliferative Factor (APF) is a sialoglycopeptide urinary biomarker of interstitial cystitis/painful bladder syndrome (IC/PBS), a chronic condition of unknown etiology with variable symptoms that ...

    • Systems-Level Modeling of Cancer-Fibroblast Interaction 

      Wadlow, Raymond C; Wittner, Ben; Finley, S. Aidan; Bergquist, Henry; Upadhyay, Rabi; Finn, Stephen; Loda, Massimo; Mahmood, Umar; Ramaswamy, Sridhar (Public Library of Science, 2009)
      Cancer cells interact with surrounding stromal fibroblasts during tumorigenesis, but the complex molecular rules that govern these interactions remain poorly understood thus hindering the development of therapeutic strategies ...

    • Untargeted metabolomics for profiling oncogene-specific metabolic signatures of prostate cancer 

      Priolo, Carmen; Loda, Massimo (Taylor & Francis, 2015)
      Oncogene-associated metabolic signatures in prostate cancer, identified by an integrative analysis of cultured cells and murine and human tumors, suggest that AKT activation results in a glycolytic phenotype whereas MYC ...

    • Whole exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer 

      Lohr, Jens G.; Adalsteinsson, Viktor A.; Cibulskis, Kristian; Choudhury, Atish D.; Rosenberg, Mara; Cruz-Gordillo, Peter; Francis, Joshua; Zhang, Cheng-Zhong; Shalek, Alex K.; Satija, Rahul; Trombetta, John T.; Lu, Diana; Tallapragada, Naren; Tahirova, Narmin; Kim, Sora; Blumenstiel, Brendan; Sougnez, Carrie; Lowe, Alarice; Wong, Bang; Auclair, Daniel; Van Allen, Eliezer M.; Nakabayashi, Mari; Lis, Rosina T.; Lee, Gwo-Shu M.; Li, Tiantian; Chabot, Matthew S.; Ly, Amy; Taplin, Mary-Ellen; Clancy, Thomas E.; Loda, Massimo; Regev, Aviv; Meyerson, Matthew; Hahn, William C.; Kantoff, Philip W.; Golub, Todd R.; Getz, Gad; Boehm, Jesse S.; Love, J. Christopher (2014)
      Comprehensive analyses of cancer genomes promise to inform prognoses and precise cancer treatments. A major barrier, however, is inaccessibility of metastatic tissue. A potential solution is to characterize circulating ...