Browsing by Author "Airoldi, Edoardo"

Now showing items 21-31 of 31

    • Predicting traffic volumes and estimating the effects of shocks in massive transportation systems 

      Silva, Ricardo; Kang, Soong Moon; Airoldi, Edoardo Maria (Proceedings of the National Academy of Sciences, 2015)
      Public transportation systems are an essential component of major cities. The widespread use of smart cards for automated fare collection in these systems offers a unique opportunity to under- stand passenger behavior at ...

    • Quantifying Condition-Dependent Intracellular Protein Levels Enables High-Precision Fitness Estimates 

      Geiler-Samerotte, Kerry A.; Hashimoto, Tatsunori; Dion, Michael F.; Budnik, Bogdan A.; Airoldi, Edoardo M.; Drummond, D. Allan (Public Library of Science, 2013)
      Countless studies monitor the growth rate of microbial populations as a measure of fitness. However, an enormous gap separates growth-rate differences measurable in the laboratory from those that natural selection can ...

    • Quantifying Sources of Variation in High-throughput Biology 

      Franks, Alexander M. (2015-05-07)
      One of the central challenges in systems biology research is disentangling relevant and irrelevant sources of variation. While the relevant quantities are always context dependent, an important distinction can be drawn ...

    • Ranking Relations Using Analogies in Biological and Information Networks 

      Silva, Ricardo; Katherine Heller; Ghahramani, Zoubin; Airoldi, Edoardo Maria (Institute of Mathematical Statistics, 2010)
      Analogical reasoning depends fundamentally on the ability to learn and generalize about relations between objects. We develop an approach to rela- tional learning which, given a set of pairs of objects S = {A[super](1) : ...

    • Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress 

      Wallace, Edward W.J.; Kear-Scott, Jamie L.; Pilipenko, Evgeny V.; Schwartz, Michael H.; Laskowski, Pawel R.; Rojek, Alexandra E.; Katanski, Christopher D.; Riback, Joshua A.; Dion, Michael F.; Franks, A; Airoldi, Edoardo Maria; Pan, Tao; Budnik, Bogdan; Drummond, D. Allan (Elsevier BV, 2015)
      Heat causes protein misfolding and aggregation, and in eukaryotic cells triggers aggregation of proteins and RNA into stress granules. We have carried out extensive proteomic studies to quantify heat-triggered aggregation ...

    • Steady-state and dynamic gene expression programs in Saccharomyces cerevisiae in response to variation in environmental nitrogen 

      Airoldi, Edoardo M.; Miller, Darach; Athanasiadou, Rodoniki; Brandt, Nathan; Abdul-Rahman, Farah; Neymotin, Benjamin; Hashimoto, Tatsu; Bahmani, Tayebeh; Gresham, David (The American Society for Cell Biology, 2016)
      Cell growth rate is regulated in response to the abundance and molecular form of essential nutrients. In Saccharomyces cerevisiae (budding yeast), the molecular form of environmental nitrogen is a major determinant of cell ...

    • A Survey of Statistical Network Models 

      Goldenberg, Anna; Zheng, Alice; Fienberg, Stephen; Airoldi, Edoardo Maria (Springer Verlag, 2009)
      Networks are ubiquitous in science and have become a focal point for discussion in everyday life. Formal statistical models for the analysis of network data have emerged as a major topic of interest in diverse areas of ...

    • Systems-Level Dynamic Analyses of Fate Change in Murine Embryonic Stem Cells 

      Airoldi, Edoardo Maria; Lu, Rong; Markowetz, Florian; Unwin, Richard; Leek, Jeffrey; MacArthur, Ben; Lachmann, Alexander; Rozov, Roye; Ma’ayan, Avi; Boyer, Laurie; Troyanskaya, Olga; Whetton, Anthony; Lemischka, Ihor (Nature Publishing Group, 2009)
      Molecular regulation of embryonic stem cell (ESC) fate involves a coordinated interaction between epigenetic, transcriptional and translational mechanisms. It is unclear how these different molecular regulatory mechanisms ...

    • Tree Preserving Embedding 

      Shieh, Albert D.; Hashimoto, Tatsunori; Airoldi, Edoardo Maria (Proceedings of the National Academy of Sciences, 2011)
      The goal of dimensionality reduction is to embed high-dimensional data in a low-dimensional space while preserving structure in the data relevant to exploratory data analysis such as clusters. However, existing dimensionality ...

    • Who wrote Ronald Reagan's radio addresses? 

      Airoldi, Edoardo Maria; Anderson, Annelise G.; Fienberg, Stephen E.; Skinner, Kiron K. (Institute of Mathematical Statistics, 2006)
      In his campaign for the U.S. presidency from 1975 to 1979, Ronald Reagan delivered over 1000 radio broadcasts. For over 600 of these we have direct evidence of Reagan's authorship. The aim of this study was to determine ...

    • Whose Ideas? Whose Words? Authorship of Ronald Reagan's Radio Addresses 

      Airoldi, Edoardo Maria; Fienberg, Stephen E.; Skinner, Kiron K. (Cambridge University Press (CUP), 2007)