Now showing items 21-31 of 31

    • Mediterranean Dietary Pattern and Cancer Risk in the EPIC Cohort 

      Couto, E; Ferrari, P; Buckland, G; Overvad, K; Dahm, C C; Tjønneland, A; Clavel-Chapelon, F; Boutron-Ruault, M-C; Cottet, V; Naska, A; Benetou, V; Kaaks, R; Rohrmann, S; Boeing, H; von Ruesten, A; Pala, V; Vineis, P; Palli, D; Tumino, R; May, A; Peeters, P H; Bueno-de-Mesquita, H B; Büchner, F L; Skeie, G; Engeset, D; Rodríguez, L; Sánchez, M-J; Amiano, P; Barricarte, A; Hallmans, G; Johansson, I; Manjer, J; Wirfärt, E; Crowe, F; Khaw, K-T; Wareham, N; Moskal, A; Slimani, N; Jenab, M; Romaguera, D; Mouw, T; Norat, T; Riboli, E; Trichopoulou, A; Boffetta, Paolo; Lagiou, Pagona; Olsen, A; Trichopoulos, Dimitrios; Allen, NE; Panico, S; Navarro, C; Lund, Emily; Gonzalez, CA (Nature Publishing Group, 2011)
      Background: Although several studies have investigated the association of the Mediterranean diet with overall mortality or risk of specific cancers, data on overall cancer risk are sparse. Methods: We examined the ...
    • Methylome Analysis and Epigenetic Changes Associated with Menarcheal Age 

      Demetriou, Christiana A.; Chen, Jia; Polidoro, Silvia; van Veldhoven, Karin; Cuenin, Cyrille; Campanella, Gianluca; Brennan, Kevin; Clavel-Chapelon, Françoise; Dossus, Laure; Kvaskoff, Marina; Drogan, Dagmar; Boeing, Heiner; Kaaks, Rudolf; Risch, Angela; Trichopoulos, Dimitrios; Lagiou, Pagona; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Panico, Salvatore; Quirós, J. Ramón; Sánchez Perez, María-José; Amiano, Pilar; Huerta Castaño, José María; Ardanaz, Eva; Onland-Moret, Charlotte; Peeters, Petra; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Romieu, Isabelle; Gallo, Valentina; Gunter, Marc; Herceg, Zdenko; Kyriacou, Kyriacos; Riboli, Elio; Flanagan, James M.; Vineis, Paolo (Public Library of Science, 2013)
      Reproductive factors have been linked to both breast cancer and DNA methylation, suggesting methylation as an important mechanism by which reproductive factors impact on disease risk. However, few studies have investigated ...
    • A Nested Case–Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Murphy, Neil; Cross, Amanda J.; Abubakar, Mustapha; Jenab, Mazda; Aleksandrova, Krasimira; Boutron-Ruault, Marie-Christine; Dossus, Laure; Racine, Antoine; Kühn, Tilman; Katzke, Verena A.; Tjønneland, Anne; Petersen, Kristina E. N.; Overvad, Kim; Quirós, J. Ramón; Jakszyn, Paula; Molina-Montes, Esther; Dorronsoro, Miren; Huerta, José-María; Barricarte, Aurelio; Khaw, Kay-Tee; Wareham, Nick; Travis, Ruth C.; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Siersema, Peter D.; Peeters, Petra H.; Ohlsson, Bodil; Ericson, Ulrika; Palmqvist, Richard; Nyström, Hanna; Weiderpass, Elisabete; Skeie, Guri; Freisling, Heinz; Kong, So Yeon; Tsilidis, Kostas; Muller, David C.; Riboli, Elio; Gunter, Marc J (Public Library of Science, 2016)
      Background: Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals ...
    • Nondense Mammographic Area and Risk of Breast Cancer 

      Pettersson, Andreas; Hankinson, Susan Elizabeth; Willett, Walter C.; Lagiou, Pagona; Trichopoulos, Dimitrios; Tamimi, Rulla May (BioMed Central, 2011)
      Introduction: The mechanisms underlying the strong association between percentage dense area on a mammogram and the risk of breast cancer are unknown. We investigated separately the absolute dense area and the absolute ...
    • Plasma Alkylresorcinols, Biomarkers of Whole-Grain Wheat and Rye Intake, and Incidence of Colorectal Cancer 

      Kyrø, Cecilie; Olsen, Anja; Landberg, Rikard; Skeie, Guri; Loft, Steffen; Åman, Per; Leenders, Max; Dik, Vincent K.; Siersema, Peter D.; Pischon, Tobias; Christensen, Jane; Overvad, Kim; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Cottet, Vanessa; Kühn, Tilman; Chang-Claude, Jenny; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; Trichopoulos, Dimitrios; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Peeters, Petra H.; Weiderpass, Elisabete; Bakken, Toril; Åsli, Lene Angell; Argüelles, Marcial; Jakszyn, Paula; Sánchez, María-José; Amiano, Pilar; Huerta, José María; Barricarte, Aurelio; Ljuslinder, Ingrid; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Ferrari, Pietro; Freisling, Heinz; Jenab, Mazda; Gunter, Marc J.; Murphy, Neil; Riboli, Eilo; Tjønneland, Anne; Bueno-de-Mesquita, H.B(as). (Oxford University Press, 2013)
      Background: Few studies have investigated the association between whole-grain intake and colorectal cancer. Because whole-grain intake estimation might be prone to measurement errors, more objective measures (eg, biomarkers) ...
    • Plasma Phyto-Oestrogens and Prostate Cancer in the European Prospective Investigation into Cancer and Nutrition 

      Travis, R C; Appleby, P N; Roddam, A W; Overvad, K; Johnsen, N F; Kaaks, R; Linseisen, J; Boeing, H; Nöthlings, U; Bueno-de-Mesquita, H B; Ros, M M; Sacerdote, C; Palli, D; Tumino, R; Berrino, F; Trichopoulou, A; Dilis, V; Chirlaque, M-D; Ardanaz, E; Larranaga, N; Suárez, L R; Sánchez, M-J; Bingham, S; Khaw, K-T; Hallmans, G; Stattin, P; Rinaldi, S; Slimani, N; Jenab, M; Riboli, E; Key, T J; Spencer, E A; Allen, N E; Olsen, A; Trichopoulos, Dimitrios; Gonzalez, C (Nature Publishing Group, 2009)
      We examined plasma concentrations of phyto-oestrogens in relation to risk for subsequent prostate cancer in a case–control study nested in the European Prospective Investigation into Cancer and Nutrition. Concentrations ...
    • Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer 

      Wang, Yufei; McKay, James D; Rafnar, Thorunn; Wang, Zhaoming; Timofeeva, Maria N; Broderick, Peter; Zong, Xuchen; Laplana, Marina; Wei, Yongyue; Han, Younghun; Lloyd, Amy; Delahaye-Sourdeix, Manon; Chubb, Daniel; Gaborieau, Valerie; Wheeler, William; Chatterjee, Nilanjan; Thorleifsson, Gudmar; Sulem, Patrick; Liu, Geoffrey; Kaaks, Rudolf; Henrion, Marc; Kinnersley, Ben; Vallée, Maxime; LeCalvez-Kelm, Florence; Stevens, Victoria L; Gapstur, Susan M; Chen, Wei V; Zaridze, David; Szeszenia-Dabrowska, Neonilia; Lissowska, Jolanta; Rudnai, Peter; Fabianova, Eleonora; Mates, Dana; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Krokan, Hans E; Gabrielsen, Maiken Elvestad; Skorpen, Frank; Vatten, Lars Johan; Njølstad, Inger; Chen, Chu; Goodman, Gary; Benhamou, Simone; Vooder, Tonu; Välk, Kristjan; Nelis, Mari; Metspalu, Andres; Lener, Marcin; Lubiński, Jan; Johansson, Mattias; Vineis, Paolo; Agudo, Antonio; Clavel-Chapelon, Francoise; Bueno-de-Mesquita, H Bas; Trichopoulos, Dimitrios; Khaw, Kay-Tee; Johansson, Mikael; Weiderpass, Elisabete; Tjønneland, Anne; Riboli, Elio; Lathrop, Mark; Scelo, Ghislaine; Albanes, Demetrius; Caporaso, Neil E; Ye, Yuanqing; Gu, Jian; Wu, Xifeng; Spitz, Margaret R; Dienemann, Hendrik; Rosenberger, Albert; Su, Li; Matakidou, Athena; Eisen, Timothy; Stefansson, Kari; Risch, Angela; Chanock, Stephen J; Christiani, David Christopher; Hung, Rayjean J; Brennan, Paul; Landi, Maria Teresa; Houlston, Richard S; Amos, Christopher I (Springer Nature, 2014)
      We conducted imputation to the 1000 Genomes Project of four genome-wide association studies of lung cancer in populations of European ancestry (11,348 cases and 15,861 controls) and genotyped an additional 10,246 cases and ...
    • Reproductive factors and risk of hormone receptor positive and negative breast cancer: a cohort study 

      Ritte, Rebecca; Tikk, Kaja; Lukanova, Annekatrin; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Dossus, Laure; Fournier, Agnès; Clavel-Chapelon, Françoise; Grote, Verena; Boeing, Heiner; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Berrino, Franco; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Quirós, José Ramón; Buckland, Genevieve; Molina-Montes, Esther; Chirlaque, María-Dolores; Ardanaz, Eva; Amiano, Pilar; Bueno-de-Mesquita, H Bas; van Gils, Carla H; Peeters, Petra HM; Wareham, Nick; Khaw, Kay-Tee; Key, Timothy J; Travis, Ruth C; Weiderpass, Elisabete; Dumeaux, Vanessa; Lund, Eliv; Sund, Malin; Andersson, Anne; Romieu, Isabelle; Rinaldi, Sabina; Vineis, Paulo; Merritt, Melissa A; Riboli, Elio; Kaaks, Rudolf (BioMed Central, 2013)
      Background: The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain. Methods: Within the EPIC cohort, Cox proportional hazards models were used to describe the relationships ...
    • Social Inequalities and Mortality in Europe – Results from a Large Multi-National Cohort 

      Gallo, Valentina; Mackenbach, Johan P.; Ezzati, Majid; Menvielle, Gwenn; Kunst, Anton E.; Rohrmann, Sabine; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; Bergmann, Manuela M.; Tjønneland, Anne; Dalton, Susanne O.; Overvad, Kim; Redondo, Maria-Luisa; Agudo, Antonio; Daponte, Antonio; Arriola, Larraitz; Navarro, Carmen; Gurrea, Aurelio Barricante; Khaw, Kay-Tee; Wareham, Nick; Key, Tim; Naska, Androniki; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Masala, Giovanna; Panico, Salvatore; Contiero, Paolo; Tumino, Rosario; Bueno-de-Mesquita, H. Bas; Siersema, Peter D.; Peeters, Petra P.; Zackrisson, Sophia; Almquist, Martin; Eriksson, Sture; Hallmans, Göran; Skeie, Guri; Braaten, Tonje; Lund, Eiliv; Illner, Anne-Kathrin; Mouw, Traci; Riboli, Elio; Vineis, Paolo (Public Library of Science, 2012)
      Background: Socio-economic inequalities in mortality are observed at the country level in both North America and Europe. The purpose of this work is to investigate the contribution of specific risk factors to social ...
    • Sources of Pre-Analytical Variations in Yield of DNA Extracted from Blood Samples: Analysis of 50,000 DNA Samples in EPIC 

      Caboux, Elodie; Lallemand, Christophe; Ferro, Gilles; Hémon, Bertrand; Mendy, Maimuna; Biessy, Carine; Sims, Matt; Wareham, Nick; Britten, Abigail; Boland, Anne; Hutchinson, Amy; Siddiq, Afshan; Vineis, Paolo; Riboli, Elio; Romieu, Isabelle; Rinaldi, Sabina; Gunter, Marc J.; Peeters, Petra H. M.; van der Schouw, Yvonne T.; Travis, Ruth; Bueno-de-Mesquita, H. Bas; Canzian, Federico; Sánchez, Maria-José; Skeie, Guri; Olsen, Karina Standahl; Lund, Eiliv; Bilbao, Roberto; Sala, Núria; Barricarte, Aurelio; Palli, Domenico; Navarro, Carmen; Panico, Salvatore; Redondo, Maria Luisa; Polidoro, Silvia; Dossus, Laure; Boutron-Ruault, Marie Christine; Clavel-Chapelon, Françoise; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Lagiou, Pagona; Boeing, Heiner; Fisher, Eva; Tumino, Rosario; Agnoli, Claudia; Hainaut, Pierre (Public Library of Science, 2012)
      The European Prospective Investigation into Cancer and nutrition (EPIC) is a long-term, multi-centric prospective study in Europe investigating the relationships between cancer and nutrition. This study has served as a ...
    • Towards an Integrated Model for Breast Cancer Etiology: The Crucial Role of the Number of Mammary Tissue-Specific Stem Cells 

      Trichopoulos, Dimitrios; Lagiou, Pagona; Adami, Hans-Olov (BioMed Central, 2004)
      Perinatal events and conditions, notably birth weight, are associated with breast cancer risk in offspring, and correlates of mammary gland mass are predictors of breast cancer risk. These findings may be interpreted as ...