Now showing items 21-40 of 86

    • Diet-Quality Scores and the Risk of Type 2 Diabetes in Men 

      de Koning, Lawrence; Chiuve, Stephanie Elizabeth; Fung, Teresa Toiyee; Willett, Walter C.; Rimm, Eric B.; Hu, Frank B. (American Diabetes Association, 2011)
      Objective: To 1) compare associations of diet-quality scores, which were inversely associated with cardiovascular disease, with incident type 2 diabetes and 2) test for differences in absolute-risk reduction across various ...
    • Dietary and Plasma Magnesium and Risk of Coronary Heart Disease Among Women 

      Chiuve, Stephanie Elizabeth; Sun, Qi; Curhan, Gary Craig; Taylor, Eric N.; Spiegelman, Donna Lynn; Willett, Walter C.; Manson, JoAnn Elisabeth; Rexrode, Kathryn Marian; Albert, Christine Marie (Blackwell Publishing Ltd, 2013)
      Background: Magnesium is associated with lower risk of sudden cardiac death, possibly through antiarrhythmic mechanisms. Magnesium influences endothelial function, inflammation, blood pressure, and diabetes, but a direct ...
    • Dietary Determinants of Age-Related Macular Degeneration 

      Wu, Juan (2016-05-04)
      Age-related macular degeneration (AMD) is the most common cause of irreversible blindness in older Americans. There has been a long standing interest in the role of diet in the development of AMD. As early as the first ...
    • Dietary fiber intake and mortality among survivors of myocardial infarction: prospective cohort study 

      Li, Shanshan; Flint, Alan; Pai, Jennifer K; Forman, John P; Hu, Frank B; Willett, Walter C; Rexrode, Kathryn M; Mukamal, Kenneth J; Rimm, Eric B (BMJ Publishing Group Ltd., 2014)
      Objective: To evaluate the associations of dietary fiber after myocardial infarction (MI) and changes in dietary fiber intake from before to after MI with all cause and cardiovascular mortality. Design: Prospective cohort ...
    • Dietary flavonoid intake and risk of incident depression in midlife and older women123 

      Chang, Shun-Chiao; Cassidy, Aedin; Willett, Walter C; Rimm, Eric B; O’Reilly, Eilis J; Okereke, Olivia I (American Society for Nutrition, 2016)
      Background: The impact of dietary flavonoid intakes on risk of depression is unclear. Objective: We prospectively examined associations between estimated habitual intakes of dietary flavonoids and depression risk. Design: ...
    • Dietary flavonoid intake and weight maintenance: three prospective cohorts of 124 086 US men and women followed for up to 24 years 

      Bertoia, Monica L; Rimm, Eric B; Mukamal, Kenneth J; Hu, Frank B; Willett, Walter C; Cassidy, Aedín (BMJ Publishing Group Ltd., 2016)
      Objective: To examine whether dietary intake of specific flavonoid subclasses (including flavonols, flavones, flavanones, flavan-3-ols, anthocyanins, and flavonoid polymers) is associated with weight change over time. ...
    • Dietary linoleic acid and risk of coronary heart disease: A systematic review and meta-analysis of prospective cohort studies 

      Farvid, Maryam; Ding, Ming; Pan, An; Sun, Qi; Chiuve, Stephanie Elizabeth; Steffen, Lyn M.; Willett, Walter C.; Hu, Frank B. (Ovid Technologies (Wolters Kluwer Health), 2014)
      Background—Previous studies on intake of linoleic acid (LA), the predominant n-6 fatty acid, and coronary heart disease (CHD) risk have generated inconsistent results. We performed a systematic review and meta-analysis of ...
    • Dietary protein sources in early adulthood and breast cancer incidence: prospective cohort study 

      Farvid, Maryam S; Cho, Eunyoung; Chen, Wendy Y; Eliassen, A Heather; Willett, Walter C (BMJ Publishing Group Ltd., 2014)
      Objective: To investigate the association between dietary protein sources in early adulthood and risk of breast cancer. Design: Prospective cohort study. Setting: Health professionals in the United States. Participants: ...
    • DNA Methylation Variants at HIF3A Locus, B-Vitamin Intake, and Long-term Weight Change: Gene-Diet Interactions in Two U.S. Cohorts 

      Huang, Tao; Zheng, Yan; Qi, Qibin; Xu, Min; Ley, Sylvia H.; Li, Yanping; Kang, Jae H.; Wiggs, Janey; Pasquale, Louis R.; Chan, Andrew T.; Rimm, Eric B.; Hunter, David J.; Manson, JoAnn E.; Willett, Walter C.; Hu, Frank B.; Qi, Lu (American Diabetes Association, 2015)
      The first epigenome-wide association study of BMI identified DNA methylation at an HIF3A locus associated with BMI. We tested the hypothesis that DNA methylation variants are associated with BMI according to intake of B ...
    • Does Diet Affect Breast Cancer Risk? 

      Holmes, Michelle D.; Willett, Walter C. (BioMed Central, 2004)
      The role of specific dietary factors in breast cancer causation is not completely resolved. Results from prospective studies do not support the concept that fat intake in middle life has a major relation to breast cancer ...
    • Effect of Low-Fat vs. Other Diet Interventions on Long-Term Weight Change in Adults: A Systematic Review and Meta-Analysis 

      Tobias, Deirdre K.; Chen, Mu; Manson, JoAnn E.; Ludwig, David S.; Willett, Walter; Hu, Frank B. (2015)
      Background: The effectiveness of low-fat diets for long-term weight loss has been debated for decades, with dozens of randomized trials (RCTs) and recent reviews giving mixed results. Methods: We conducted a random effects ...
    • Effects of the Dietary Approaches to Stop Hypertension (DASH) Eating Plan on Cardiovascular Risks among Type 2 Diabetic Patients: A Randomized Crossover Clinical Trial 

      Azadbakht, Leila; Fard, Nafiseh Rashidi Pour; Karimi, Majid; Baghaei, Mohammad Hassan; Surkan, Pamela J.; Rahimi, Majid; Esmaillzadeh, Ahmad; Willett, Walter C. (American Diabetes Association, 2011)
      Objective: To determine the effects of the Dietary Approaches to Stop Hypertension (DASH) eating pattern on cardiometabolic risks in type 2 diabetic patients. Research design and methods: A randomized crossover clinical ...
    • Fluorescent Oxidation Products and Risk of Coronary Heart Disease: A Prospective Study in Women 

      Jensen, Majken K.; Wang, Yushan; Rimm, Eric B.; Townsend, Mary K.; Willett, Walter; Wu, Tianying (Blackwell Publishing Ltd, 2013)
      Background: Oxidative stress is implicated in the etiology of coronary heart disease (CHD). New measures to capture oxidative stress are warranted. Fluorescent oxidation products (FlOPs) can be measured in plasma and have ...
    • Food Predictors of Plasma Carotenoids 

      Hendrickson, Sara J.; Willett, Walter C.; Rosner, Bernard A.; Eliassen, A. Heather (MDPI, 2013)
      Empirical prediction models that weight food frequency questionnaire (FFQ) food items by their relation to nutrient biomarker concentrations may estimate nutrient exposure better than nutrient intakes derived from food ...
    • Fried food consumption, genetic risk, and body mass index: gene-diet interaction analysis in three US cohort studies 

      Qi, Qibin; Chu, Audrey Y; Kang, Jae H; Huang, Jinyan; Rose, Lynda M; Jensen, Majken K; Liang, Liming; Curhan, Gary C; Pasquale, Louis R; Wiggs, Janey L; De Vivo, Immaculata; Chan, Andrew T; Choi, Hyon K; Tamimi, Rulla M; Ridker, Paul M; Hunter, David J; Willett, Walter C; Rimm, Eric B; Chasman, Daniel I; Hu, Frank B; Qi, Lu (BMJ Publishing Group Ltd., 2014)
      Objective: To examine the interactions between genetic predisposition and consumption of fried food in relation to body mass index (BMI) and obesity. Design: Prospective cohort study. Setting: Health professionals in the ...
    • Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies 

      Muraki, Isao; Imamura, Fumiaki; Manson, JoAnn E; Hu, Frank B; Willett, Walter C; van Dam, Rob M; Sun, Qi (BMJ Publishing Group Ltd., 2013)
      Objective: To determine whether individual fruits are differentially associated with risk of type 2 diabetes. Design: Prospective longitudinal cohort study. Setting: Health professionals in the United States. Participants: ...
    • Gender-Related Differences in the Prevalence of Cardiovascular Disease Risk Factors and their Correlates in Urban Tanzania 

      Njelekela, Marina A; Mpembeni, Rose; Mligiliche, Nuru L; Mtabaji, Jacob; Muhihi, Alfa; Spiegelman, Donna Lynn; Hertzmark, Ellen; Liu, Enju; Finkelstein, Julia Leigh; Fawzi, Wafaie W.; Willett, Walter C. (BioMed Central, 2009)
      Background: Urban areas in Africa suffer a serious problem with dual burden of infectious diseases and emerging chronic diseases such as cardiovascular diseases (CVD) and diabetes which pose a serious threat to population ...
    • Genetic risk variants associated with in situ breast cancer 

      Campa, Daniele; Barrdahl, Myrto; Gaudet, Mia M.; Black, Amanda; Chanock, Stephen J.; Diver, W. Ryan; Gapstur, Susan M.; Haiman, Christopher; Hankinson, Susan; Hazra, Aditi; Henderson, Brian; Hoover, Robert N.; Hunter, David J.; Joshi, Amit D.; Kraft, Peter; Le Marchand, Loic; Lindström, Sara; Willett, Walter; Travis, Ruth C.; Amiano, Pilar; Siddiq, Afshan; Trichopoulos, Dimitrios; Sund, Malin; Tjønneland, Anne; Weiderpass, Elisabete; Peeters, Petra H.; Panico, Salvatore; Dossus, Laure; Ziegler, Regina G.; Canzian, Federico; Kaaks, Rudolf (BioMed Central, 2015)
      Introduction: Breast cancer in situ (BCIS) diagnoses, a precursor lesion for invasive breast cancer, comprise about 20 % of all breast cancers (BC) in countries with screening programs. Family history of BC is considered ...
    • A Genome-Wide “Pleiotropy Scan” Does Not Identify New Susceptibility Loci for Estrogen Receptor Negative Breast Cancer 

      Campa, Daniele; Barrdahl, Myrto; Tsilidis, Konstantinos K.; Severi, Gianluca; Diver, W. Ryan; Siddiq, Afshan; Chanock, Stephen; Hoover, Robert N.; Ziegler, Regina G.; Berg, Christine D.; Buys, Saundra S.; Haiman, Christopher A.; Henderson, Brian E.; Schumacher, Fredrick R.; Le Marchand, Loïc; Flesch-Janys, Dieter; Lindström, Sara; Hunter, David J.; Hankinson, Susan E.; Willett, Walter C.; Kraft, Peter; Cox, David G.; Khaw, Kay-Tee; Tjønneland, Anne; Dossus, Laure; Trichopoulos, Dimitrios; Panico, Salvatore; van Gils, Carla H.; Weiderpass, Elisabete; Barricarte, Aurelio; Sund, Malin; Gaudet, Mia M.; Giles, Graham; Southey, Melissa; Baglietto, Laura; Chang-Claude, Jenny; Kaaks, Rudolf; Canzian, Federico (Public Library of Science, 2014)
      Approximately 15–30% of all breast cancer tumors are estrogen receptor negative (ER−). Compared with ER-positive (ER+) disease they have an earlier age at onset and worse prognosis. Despite the vast number of risk variants ...
    • Habitual intake of flavonoid subclasses and risk of colorectal cancer in 2 large prospective cohorts12 

      Nimptsch, Katharina; Zhang, Xuehong; Cassidy, Aedín; Song, Mingyang; O’Reilly, Éilis J; Lin, Jennifer H; Pischon, Tobias; Rimm, Eric B; Willett, Walter C; Fuchs, Charles S; Ogino, Shuji; Chan, Andrew T; Giovannucci, Edward L; Wu, Kana (American Society for Nutrition, 2016)
      Background: Flavonoids inhibit the growth of colon cancer cells in vitro. In a secondary analysis of a randomized controlled trial, the Polyp Prevention Trial, a higher intake of one subclass, flavonols, was statistically ...