Now showing items 21-40 of 42

    • Immunogenicity of a Killed Bivalent (O1 and O139) Whole Cell Oral Cholera Vaccine, Shanchol, in Haiti 

      Charles, Richelle C.; Hilaire, Isabelle J.; Mayo-Smith, Leslie M.; Teng, Jessica E.; Jerome, J. Gregory; Franke, Molly F.; Saha, Amit; Yu, Yanan; Kováč, Paul; Calderwood, Stephen B.; Ryan, Edward T.; LaRocque, Regina C.; Almazor, Charles P.; Qadri, Firdausi; Ivers, Louise C.; Harris, Jason B. (Public Library of Science, 2014)
      Background: Studies of the immunogenicity of the killed bivalent whole cell oral cholera vaccine, Shanchol, have been performed in historically cholera-endemic areas of Asia. There is a need to assess the immunogenicity ...
    • Immunologic Responses to Vibrio cholerae in Patients Co-Infected with Intestinal Parasites in Bangladesh 

      Bhuiyan, Taufiqur R.; Chowdhury, Fahima; Khan, Ashraful I.; Logvinenko, Tanya; Kendall, Jennifer; Faruque, Abu S. G.; Nagler, Cathryn R.; Qadri, Firdausi; Harris, Jason B.; Podolsky, Michael Jeffrey; Larocque, Regina Celes; Ryan, Edward Thomas; Calderwood, Stephen Beaven (Public Library of Science, 2009)
      Background: Infection with intestinal helminths is common and may contribute to the decreased efficacy of Vibrio cholerae vaccines in endemic compared to non-endemic areas. However, the immunomodulatory effects of concomitant ...
    • Individuals with Le(a+b−) Blood Group have Increased Susceptibility to Symptomatic \(Vibrio\) \(cholerae\) O1 Infection 

      Arifuzzaman, Mohammad; Ahmed, Tanvir; Chowdhury, Fahima; Rashu, Rasheduzzaman; Khan, Ashraful I.; Bhuiyan, Taufiqur Rahman; Qadri, Firdausi; Rahman, Mohammad Arif; Larocque, Regina Celes; Harris, Jason B.; Ryan, Edward Thomas; Calderwood, Stephen Beaven (Public Library of Science, 2011)
      Background: Human genetic factors such as blood group antigens may affect the severity of infectious diseases. Presence of specific ABO and Lewis blood group antigens has been shown previously to be associated with the ...
    • Informal urban settlements and cholera risk in Dar es Salaam, Tanzania 

      Penrose, Katherine; Castro, Marcia C. de; Werema, Japhet; Ryan, Edward Thomas (Public Library of Science, 2010)
      Background: As a result of poor economic opportunities and an increasing shortage of affordable housing, much of the spatial growth in many of the world's fastest-growing cities is a result of the expansion of informal ...
    • A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever 

      Park, Ki Soo; Chung, Hyun Jung; Khanam, Farhana; Lee, Hakho; Rashu, Rasheduzzaman; Bhuiyan, Md. Taufiqur; Berger, Amanda; Harris, Jason B.; Calderwood, Stephen B.; Ryan, Edward T.; Qadri, Firdausi; Weissleder, Ralph; Charles, Richelle C. (Nature Publishing Group, 2016)
      There is currently no widely available optimal assay for diagnosing patients with enteric fever. Here we present a novel assay designed to detect amplified Salmonella nucleic acid (mRNA) using magneto-DNA probes and a ...
    • Natural Selection in a Bangladeshi Population from the Cholera-Endemic Ganges River Delta 

      Karlsson, Elinor Kathryn; Harris, J. B.; Tabrizi, Shervin; Rahman, A.; Shlyakhter, Ilya; Patterson, N.; O, C.; Schaffner, Stephen; Gupta, S.; Chowdhury, F.; Sheikh, A.; Shin, O. S.; Ellis, C.; Becker, C. E.; Stuart, L. M.; Calderwood, Stephen Beaven; Ryan, Edward Thomas; Qadri, F.; Sabeti, Pardis Christine; Larocque, Regina Celes (American Association for the Advancement of Science (AAAS), 2013)
      As an ancient disease with high fatality, cholera has likely exerted strong selective pressure on affected human populations. We performed a genome-wide study of natural selection in a population from the Ganges River ...
    • P09-20 LB. Ultra-Deep Sequencing of Full-Length HIV-1 Genomes Identifies Rapid Viral Evolution During Acute Infection 

      Henn, MR; Lennon, N; Malboeuf, C; Charlebois, P; Philips, L; Berical, A; Erlich, R; Kemper, M; Axten, K; Brumme, Z; Brumme, C; Jessen, H; Nusbaum, C; Birren, B; Allen, TM; Boutwell, Christian Lane; Power, K; Gladden, Andrew B; Levin, Jonathan M.; Casali, Monica; Berlin, A; Anderson, S; Streeck, Hendrik; Ryan, Edward Thomas; Wang, Y; Green, L; Russ, Christiana Marie; Rosenberg, Eric Scott; Altfeld, Marcus; Walker, Bruce David (BioMed Central, 2009)
    • Plasma Leptin Levels in Children Hospitalized with Cholera in Bangladesh 

      Falkard, Brie; Uddin, Taher; Arifur Rahman, M.; Franke, Molly F.; Aktar, Amena; Uddin, Muhammad Ikhtear; Bhuiyan, Taufiqur Rahman; Leung, Daniel T.; Charles, Richelle C.; Larocque, Regina C.; Harris, Jason B.; Calderwood, Stephen B.; Qadri, Firdausi; Ryan, Edward T. (The American Society of Tropical Medicine and Hygiene, 2015)
      Vibrio cholerae, the cause of cholera, induces both innate and adaptive immune responses in infected humans. Leptin is a hormone that plays a role in both metabolism and mediating immune responses. We characterized leptin ...
    • Pre-Travel Health Care of Immigrants Returning Home to Visit Friends and Relatives 

      Larocque, Regina Celes; Deshpande, Bhushan R.; Rao, Sowmya R.; Brunette, Gary W.; Sotir, Mark J.; Jentes, Emily S.; Ryan, Edward Thomas (The American Society of Tropical Medicine and Hygiene, 2013)
      Immigrants returning home to visit friends and relatives (VFR travelers) are at higher risk of travel-associated illness than other international travelers. We evaluated 3,707 VFR and 17,507 non-VFR travelers seen for ...
    • Pre-Travel Medical Preparation of Business and Occupational Travelers: An Analysis of the Global TravEpiNet Consortium, 2009 to 2012 

      Khan, Nomana M.; Jentes, Emily S.; Brown, Clive; Han, Pauline; Rao, Sowmya R.; Kozarsky, Phyllis; Hagmann, Stefan H.F.; LaRocque, Regina C.; Ryan, Edward T. (Lippincott Williams & Wilkins, 2015)
      Objectives: The aim of the study was to understand more about pre-travel preparations and itineraries of business and occupational travelers. Methods: De-identified data from 18 Global TravEpiNet clinics from January 2009 ...
    • Pre-Travel Preparation of US Travelers Going Abroad to Provide Humanitarian Service, Global TravEpiNet 2009–2011 

      Stoney, Rhett J.; Jentes, Emily S.; Sotir, Mark J.; Kozarsky, Phyllis; Rao, Sowmya R.; LaRocque, Regina C.; Ryan, Edward T. (The American Society of Tropical Medicine and Hygiene, 2014)
      We analyzed characteristics of humanitarian service workers (HSWs) seen pre-travel at Global TravEpiNet (GTEN) practices during 2009–2011. Of 23,264 travelers, 3,663 (16%) travelers were classified as HSWs. Among HSWs, ...
    • Refusal of recommended travel-related vaccines among U.S. international travellers in Global TravEpiNet 

      Lammert, Sara M.; Rao, Sowmya R.; Jentes, Emily S.; Fairley, Jessica K.; Erskine, Stefanie; Walker, Allison T.; Hagmann, Stefan H.; Sotir, Mark J.; Ryan, Edward T.; LaRocque, Regina C. (Oxford University Press, 2016)
      Background: International travellers are at risk of travel-related, vaccine-preventable diseases. More data are needed on the proportion of travellers who refuse vaccines during a pre-travel health consultation and their ...
    • Severe, Acute Watery Diarrhea in an Adult 

      Chowdhury, Fahima; Khan, Ashraful Islam; Faruque, Abu Syed Golam; Ryan, Edward Thomas (Public Library of Science, 2010)
    • Single-Cell Analysis of the Plasmablast Response to Vibrio cholerae Demonstrates Expansion of Cross-Reactive Memory B Cells 

      Kauffman, Robert C.; Bhuiyan, Taufiqur R.; Nakajima, Rie; Mayo-Smith, Leslie M.; Rashu, Rasheduzzaman; Hoq, Mohammad Rubel; Chowdhury, Fahima; Khan, Ashraful Islam; Rahman, Atiqur; Bhaumik, Siddhartha K.; Harris, Levelle; O'Neal, Justin T.; Trost, Jessica F.; Alam, Nur Haq; Jasinskas, Algis; Dotsey, Emmanuel; Kelly, Meagan; Charles, Richelle C.; Xu, Peng; Kováč, Pavol; Calderwood, Stephen B.; Ryan, Edward T.; Felgner, Phillip L.; Qadri, Firdausi; Wrammert, Jens; Harris, Jason B. (American Society for Microbiology, 2016)
      ABSTRACT We characterized the acute B cell response in adults with cholera by analyzing the repertoire, specificity, and functional characteristics of 138 monoclonal antibodies (MAbs) generated from single-cell-sorted ...
    • Structural Basis for Continued Antibody Evasion by the SARS-CoV-2 Receptor-Binding Domain 

      Nabel, Katherine G.; Clark, Sarah A.; Shankar, Sundaresh; Pan, Junhua; Clark, Lars; Yang, Pan; Coscia, Adrian; McKay, Lindsay G.A.; Varnum, Haley; Brusic, Vesna; Tolan, Nicole V.; Zhou, Guohai; Desjardins, Michaël; Turbett, Sarah E.; Kanjilal, Sanjat; Sherman, Amy; Dighe, Anand; LaRocque, Regina C.; Ryan, Edward; Tylek, Casey; Cohen-Solal, Joel F.; Darcy, Andhao T.; Tavella, Davide; Clabbers, Anca; Fan, Yao; Griffiths, Anthony; Correia, Ivan R.; Seagal, Jane; Baden, Lindsey; Charles, Richelle; Abraham, Jonathan (2021-12-02)
      Many studies have examined the impact of SARS-CoV-2 variants on neutralizing antibody activity after they have become dominant strains. Here, we evaluate the consequences of further viral evolution. We demonstrate mechanisms ...
    • Susceptibility to Vibrio cholerae Infection in a Cohort of Household Contacts of Patients with Cholera in Bangladesh 

      Chowdhury, Fahima; Khan, Ashraful I.; Logvinenko, Tanya; Faruque, Abu S. G.; Qadri, Firdausi; Ko, Albert I.; Harris, Jason B.; Larocque, Regina Celes; Ryan, Edward Thomas; Calderwood, Stephen Beaven (Public Library of Science, 2008)
      Background: Despite recent progress in understanding the molecular basis of Vibrio cholerae pathogenesis, there is relatively little knowledge of the factors that determine the variability in human susceptibility to V. ...
    • Transformation of the Developing World: Socioeconomic Matrix 

      Carroll, Dennis; Gardner, Pierce; Kay, Bradford A.; Osterholm, Michael; Ryan, Edward Thomas (Centers for Disease Control and Prevention, 2004)
    • Travel Characteristics and Yellow Fever Vaccine Usage Among US Global TravEpiNet Travelers Visiting Countries with Risk of Yellow Fever Virus Transmission, 2009–2011 

      Jentes, Emily S.; Han, Pauline; Gershman, Mark D.; Rao, Sowmya R.; LaRocque, Regina C.; Staples, J. Erin; Ryan, Edward T. (The American Society of Tropical Medicine and Hygiene, 2013)
      Yellow fever (YF) vaccine-associated serious adverse events and changing YF epidemiology have challenged healthcare providers to vaccinate only travelers whose risk of YF during travel is greater than their risk of adverse ...
    • Typhoid Fever in Young Children in Bangladesh: Clinical Findings, Antibiotic Susceptibility Pattern and Immune Responses 

      Khanam, Farhana; Sayeed, Md. Abu; Choudhury, Feroza Kaneez; Sheikh, Alaullah; Ahmed, Dilruba; Goswami, Doli; Hossain, Md. Lokman; Brooks, Abdullah; Calderwood, Stephen B.; Charles, Richelle C.; Cravioto, Alejandro; Ryan, Edward T.; Qadri, Firdausi (Public Library of Science, 2015)
      Background: Children bear a large burden of typhoid fever caused by Salmonella enterica serotype Typhi (S. Typhi) in endemic areas. However, immune responses and clinical findings in children are not well defined. Here, ...
    • Use of Japanese Encephalitis Vaccine in US Travel Medicine Practices in Global TravEpiNet 

      Deshpande, Bhushan R.; Rao, Sowmya R.; Jentes, Emily S.; Hills, Susan L.; Fischer, Marc; Gershman, Mark D.; Brunette, Gary W.; Ryan, Edward T.; LaRocque, Regina C. (The American Society of Tropical Medicine and Hygiene, 2014)
      Few data regarding the use of Japanese encephalitis (JE) vaccine in clinical practice are available. We identified 711 travelers at higher risk and 7,578 travelers at lower risk for JE who were seen at US Global TravEpiNet ...