Browsing by Author "Desai, Michael"
Now showing items 21-21 of 21
-
The Structure of Genealogies in the Presence of Purifying Selection: a "Fitness-Class Coalescent"
Walczak, Aleksandra M.; Nicolaisen, Lauren Elisabeth; Plotkin, Joshua B.; Desai, Michael M (Genetics Society of America, 2012)Compared to a neutral model, purifying selection distorts the structure of genealogies and hence alters the patterns of sampled genetic variation. Although these distortions may be common in nature, our understanding of ...