Now showing items 21-40 of 50

    • Increased diffusivity in superior temporal gyrus in patients with schizophrenia: A Diffusion Tensor Imaging study 

      Lee, KangUk; Yoshida, Takeshi; Kubicki, Marek R.; Bouix, Sylvain; Westin, Carl-Fredrik; Kindlmann, Gordon; Niznikiewicz, Margaret A.; Cohen, Adam Brian; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2009)
      Background: Superior temporal gyrus (STG) volume reduction is one of the most consistent findings in schizophrenia. The goal of this study was to conduct the first diffusion tensor imaging (DTI) study to investigate altered ...
    • Increased Gray Matter Diffusion Anisotropy in Patients with Persistent Post-Concussive Symptoms following Mild Traumatic Brain Injury 

      Bouix, Sylvain; Pasternak, Ofer; Rathi, Yogesh; Pelavin, Paula E.; Zafonte, Ross; Shenton, Martha E. (Public Library of Science, 2013)
      A significant percentage of individuals diagnosed with mild traumatic brain injury (mTBI) experience persistent post-concussive symptoms (PPCS). Little is known about the pathology of these symptoms and there is often no ...
    • Local white matter geometry from diffusion tensor gradients 

      Savadjiev, Peter; Kindlmann, Gordon L.; Bouix, Sylvain; Shenton, Martha Elizabeth; Westin, Carl-Fredrik (Elsevier BV, 2010)
      We introduce a mathematical framework for computing geometrical properties of white matter fibres directly from diffusion tensor fields. The key idea is to isolate the portion of the gradient of the tensor field corresponding ...
    • Longitudinal loss of gray matter volume in patients with first-episode schizophrenia: DARTEL automated analysis and ROI validation 

      Asami, Takeshi; Bouix, Sylvain; Whitford, Thomas; Shenton, Martha Elizabeth; Salisbury, Dean F.; McCarley, Robert William (Elsevier BV, 2012)
      Region of Interest (ROI) longitudinal studies have detected progressive gray matter (GM) volume reductions in patients with first-episode schizophrenia (FESZ). However, there are only a few longitudinal voxel-based morphometry ...
    • Medial Frontal White and Gray Matter Contributions to General Intelligence 

      Ohtani, Toshiyuki; Nestor, Paul G.; Bouix, Sylvain; Saito, Yukiko; Hosokawa, Taiga; Kubicki, Marek (Public Library of Science, 2014)
      The medial orbitofrontal cortex (mOFC) and rostral anterior cingulate cortex (rACC) are part of a wider neural network that plays an important role in general intelligence and executive function. We used structural brain ...
    • Multi-tensor investigation of orbitofrontal cortex tracts affected in subcaudate tractotomy 

      Yang, Jimmy Chen; Papadimitriou, George; Eckbo, Ryan; Yeterian, Edward H.; Liang, Lichen; Dougherty, Darin Dean; Bouix, Sylvain; Rathi, Yogesh; Shenton, Martha Elizabeth; Kubicki, Marek R.; Eskandar, Emad; Makris, Nikos (Springer Science + Business Media, 2014)
      Subcaudate tractotomy (SCT) is a neurosurgical lesioning procedure that can reduce symptoms in medically intractable obsessive compulsive disorder (OCD). Due to the putative importance the orbitofrontal cortex (OFC) in ...
    • Neocortical Gray Matter Volume in First-Episode Schizophrenia and First-Episode Affective Psychosis: A Cross-Sectional and Longitudinal MRI Study 

      Nakamura, Motoaki; Salisbury, Dean F.; Hirayasu, Yoshio; Bouix, Sylvain; Pohl, Kilian M.; Yoshida, Takeshi; Koo, Min-Seong; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2007)
      Background: Overall neocortical gray matter (NCGM) volume has not been studied in first-episode schizophrenia (FESZ) at first hospitalization or longitudinally to evaluate progression, nor has it been compared with ...
    • Neuroimaging in repetitive brain trauma 

      Ng, Thomas SC; Lin, Alexander P; Koerte, Inga K; Pasternak, Ofer; Liao, Huijun; Merugumala, Sai; Bouix, Sylvain; Shenton, Martha E. (BioMed Central, 2014)
      Sports-related concussions are one of the major causes of mild traumatic brain injury. Although most patients recover completely within days to weeks, those who experience repetitive brain trauma (RBT) may be at risk for ...
    • Neuropsychological Outcome and Diffusion Tensor Imaging in Complicated versus Uncomplicated Mild Traumatic Brain Injury 

      Panenka, William J.; Lange, Rael T.; Bouix, Sylvain; Shewchuk, Jason R.; Heran, Manraj K. S.; Brubacher, Jeffrey R.; Eckbo, Ryan; Shenton, Martha E.; Iverson, Grant L. (Public Library of Science, 2015)
      This study examined whether intracranial neuroimaging abnormalities in those with mild traumatic brain injury (MTBI) (i.e., “complicated” MTBIs) are associated with worse subacute outcomes as measured by cognitive testing, ...
    • On Diffusion Tensor Estimation 

      Niethammer, Marc; Estepar, Raul San Jose; Bouix, Sylvain; Shenton, Martha Elizabeth; Westin, Carl-Fredrik (IEEE, 2006)
      In this paper we propose a formal formulation for the estimation of Diffusion Tensors in the space of symmetric positive semidefinite (PSD) tensors. Traditionally, diffusion tensor model estimation has been carried out ...
    • On evaluating brain tissue classifiers without a ground truth 

      Bouix, Sylvain; Martin-Fernandez, Marcos; Ungar, Lida; Nakamura, Motoaki; Koo, Min-Seong; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2007)
      In this paper, we present a set of techniques for the evaluation of brain tissue classifiers on a large data set of MR images of the head. Due to the difficulty of establishing a gold standard for this type of data, we ...
    • Outlier Rejection for Diffusion Weighted Imaging 

      Niethammer, Marc; Bouix, Sylvain; Aja-Fernández, Santiago; Westin, Carl-Fredrik; Shenton, Martha Elizabeth (Springer, 2007)
      This paper introduces an outlier rejection and signal reconstruction method for high angular resolution diffusion weighted imaging. The approach is based on the thresholding of Laplacian measurements over the sphere of the ...
    • A prospective longitudinal volumetric MRI study of superior temporal gyrus gray matter and amygdala–hippocampal complex in chronic schizophrenia 

      Yoshida, Takeshi; McCarley, Robert William; Nakamura, Motoaki; Lee, KangUk; Koo, Min-Seong; Bouix, Sylvain; Salisbury, Dean F.; Morra, Lindsay; Shenton, Martha Elizabeth; Niznikiewicz, Margaret A. (Elsevier BV, 2009)
      A progressive post-onset decrease in gray matter volume 1.5 years after first hospitalization in schizophrenia has been shown in superior temporal gyrus (STG). However, it is still controversial whether progressive volume ...
    • Reduced fractional anisotropy and axial diffusivity in white matter in 22q11.2 deletion syndrome: A pilot study 

      Kikinis, Zora; Asami, T.; Bouix, Sylvain; Finn, C.T.; Ballinger, T.; Tworog-Dube, E.; Kucherlapati, Raju; Kikinis, Ron; Shenton, Martha Elizabeth; Kubicki, Marek R. (Elsevier BV, 2012)
      Individuals with 22q11.2 deletion syndrome (22q11.2DS) evince a 30% incidence of schizophrenia. We compared the white matter (WM) of 22q11.2DS patients without schizophrenia to a group matched healthy controls using ...
    • Reduced interhemispheric connectivity in schizophrenia-tractography based segmentation of the corpus callosum 

      Kubicki, Marek R.; Styner, M; Bouix, Sylvain; Gerig, G; Markant, D; Smith, K; Kikinis, Ron; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2008)
      Background: A reduction in interhemispheric connectivity is thought to contribute to the etiology of schizophrenia. Diffusion Tensor Imaging (DTI) measures the diffusion of water and can be used to describe the integrity ...
    • A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury 

      Shenton, Martha Elizabeth; Hamoda, Hesham; Schneiderman, J. S.; Bouix, Sylvain; Pasternak, Ofer; Rathi, Yogesh; Vu, M.-A.; Purohit, Maulik Prafull; Helmer, Karl G.; Koerte, Inga Katharina; Lin, Alexander Peter; Westin, Carl-Fredrik; Kikinis, Ron; Kubicki, Marek R.; Stern, R. A.; Zafonte, Ross Dennis (Springer Science + Business Media, 2012)
      Mild traumatic brain injury (mTBI), also referred to as concussion, remains a controversial diagnosis because the brain often appears quite normal on conventional computed tomography (CT) and magnetic resonance imaging ...
    • Shape abnormalities of caudate nucleus in schizotypal personality disorder 

      Levitt, James Jonathan; Styner, Martin; Niethammer, Marc; Bouix, Sylvain; Koo, Min-Seong; Voglmaier, Martina M.; Dickey, Chandlee C.; Niznikiewicz, Margaret A.; Kikinis, Ron; McCarley, Robert, W.; Shenton, Martha Elizabeth (Elsevier BV, 2009)
      Background: Previously, we reported abnormal volume and global shape in the caudate nucleus in schizotypal personality disorder (SPD). Here, we use a new shape measure which importantly permits local in addition to global ...
    • Smaller Neocortical Gray Matter and Larger Sulcal Cerebrospinal Fluid Volumes in Neuroleptic-Naive Women With Schizotypal Personality Disorder 

      Koo, Min-Seong; Dickey, Chandlee C.; Park, Hae-Jeong; Kubicki, Marek R.; Ji, Na Young; Bouix, Sylvain; Pohl, Kilian M.; Levitt, James Jonathan; Nakamura, Motoaki; Shenton, Martha Elizabeth; McCarley, Robert William (American Medical Association (AMA), 2006)
      Context: Structural brain abnormalities, including larger cerebrospinal fluid (CSF) volumes, have been observed in men diagnosed as having schizotypal personality disorder (SPD). Objectives: To determine whether women ...
    • Sparse Multi-Shell Diffusion Imaging 

      Rathi, Yogesh; Michailovich, O.; Setsompop, Kawin; Bouix, Sylvain; Shenton, Martha Elizabeth; Westin, Carl-Fredrik (Springer Science + Business Media, 2011)
      Diffusion magnetic resonance imaging (dMRI) is an important tool that allows non-invasive investigation of neural architecture of the brain. The data obtained from these in-vivo scans provides important information about ...
    • Sparse Texture Active Contour 

      Gao, Yi; Bouix, Sylvain; Shenton, Martha Elizabeth; Tannenbaum, Allen (Institute of Electrical and Electronics Engineers (IEEE), 2013)
      In image segmentation, we are often interested in using certain quantities to characterize the object, and perform the classification based on them: mean intensity, gradient magnitude, responses to certain predefined ...