Now showing items 21-21 of 21

    • Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4 

      Junker, Yvonne; Zeissig, Sebastian; Kim, Seong-Jun; Barisani, Donatella; Wieser, Herbert; Leffler, Daniel A.; Zevallos, Victor; Libermann, Towia A.; Dillon, Simon; Freitag, Tobias L.; Kelly, Ciaran P.; Schuppan, Detlef (The Rockefeller University Press, 2012)
      Ingestion of wheat, barley, or rye triggers small intestinal inflammation in patients with celiac disease. Specifically, the storage proteins of these cereals (gluten) elicit an adaptive Th1-mediated immune response in ...