Now showing items 21-36 of 36

    • Movement-generated afference paired with transcranial magnetic stimulation: an associative stimulation paradigm 

      Edwards, Dylan J; Dipietro, Laura; Demirtas-Tatlidede, Asli; Medeiros, Ana H; Thickbroom, Gary W; Mastaglia, Francis L; Krebs, Hermano I; Pascual-Leone, Alvaro (BioMed Central, 2014)
      Background: A peripheral nerve stimulus can enhance or suppress the evoked response to transcranial magnetic stimulation (TMS) depending on the latency of the preceding peripheral nerve stimulation (PNS) pulse. Similarly, ...
    • N100 Repetition Suppression Indexes Neuroplastic Defects in Clinical High Risk and Psychotic Youth 

      Gonzalez-Heydrich, Joseph; Bosquet Enlow, Michelle; D'Angelo, Eugene; Seidman, Larry J.; Gumlak, Sarah; Kim, April; Woodberry, Kristen A.; Rober, Ashley; Tembulkar, Sahil; O'Donnell, Kyle; Hamoda, Hesham M.; Kimball, Kara; Rotenberg, Alexander; Oberman, Lindsay M.; Pascual-Leone, Alvaro; Keshavan, Matcheri S.; Duffy, Frank H. (Hindawi Publishing Corporation, 2016)
      Highly penetrant mutations leading to schizophrenia are enriched for genes coding for N-methyl-D-aspartate receptor signaling complex (NMDAR-SC), implicating plasticity defects in the disease's pathogenesis. The importance ...
    • Physiological consequences of abnormal connectivity in a developmental epilepsy 

      Shafi, Mouhsin; Vernet, Marine; Klooster, Debby; Chu, Catherine Jean; Boric, Katica; Barnard, Mollie E.; Romatoski, Kelsey; Westover, Michael Brandon; Christodoulou, Joanna A.; Gabrieli, John D. E.; Whitfield-Gabrieli, Susan; Pascual-Leone, Alvaro; Chang, Bernard Shaw-Farn (Wiley-Blackwell, 2015)
      Objective: Many forms of epilepsy are associated with aberrant neuronal connections, but the relationship between such pathological connectivity and the underlying physiological predisposition to seizures is unclear. We ...
    • Preoperative Cognitive Performance Dominates Risk for Delirium Among Older Adults 

      Jones, Richard N.; Marcantonio, Edward; Saczynski, Jane S.; Tommet, Douglas; Gross, Alden L.; Travison, Thomas; Alsop, David; Schmitt, Eva M.; Fong, Tamara; Cizginer, Sevdenur; Shafi, Mouhsin; Pascual-Leone, Alvaro; Inouye, Sharon (SAGE Publications, 2016-11)
      Background Cognitive impairment is a well-recognized risk factor for delirium. Our goal was to determine if the level of cognitive performance across the non-demented cognitive ability spectrum is correlated with delirium ...
    • Processing Nouns and Verbs in the Left Frontal Cortex: A Transcranial Magnetic Stimulation Study 

      Cappelletti, Marinella; Fregni, Felipe; Shapiro, Kevin; Pascual-Leone, Alvaro; Caramazza, Alfonso (Massachusetts Institute of Technology Press, 2008)
      Neuropsychological and neurophysiological studies suggest that the production of verbs in speech depends on cortical regions in the left frontal lobe. However, the precise topography of these regions, and their functional ...
    • Reliability of Resting-State Microstate Features in Electroencephalography 

      Khanna, Arjun; Pascual-Leone, Alvaro; Farzan, Faranak (Public Library of Science, 2014)
      Background: Electroencephalographic (EEG) microstate analysis is a method of identifying quasi-stable functional brain states (“microstates”) that are altered in a number of neuropsychiatric disorders, suggesting their ...
    • Risk Taking in Hospitalized Patients with Acute and Severe Traumatic Brain Injury 

      Fecteau, Shirley; Levasseur-Moreau, Jean; García-Molina, Alberto; Kumru, Hatiche; Vergara, Raúl Pelayo; Bernabeu, Monste; Roig, Teresa; Pascual-Leone, Alvaro; Tormos, José Maria (Public Library of Science, 2013)
      Rehabilitation can improve cognitive deficits observed in patients with traumatic brain injury (TBI). However, despite rehabilitation, the ability of making a choice often remains impaired. Risk taking is a daily activity ...
    • The Role of the Parietal Lobe in Visual Extinction Studied with Transcranial Magnetic Stimulation 

      Battelli, Lorella; Alvarez, George Angelo; Carlson, Thomas; Pascual-Leone, Alvaro (University of Chicago Press, 2009)
      Interhemispheric competition between homologous areas in the human brain is believed to be involved in a wide variety of human behaviors from motor activity to visual perception and particularly attention. For example, ...
    • Suppression of Motor Cortical Excitability in Anesthetized Rats by Low Frequency Repetitive Transcranial Magnetic Stimulation 

      Muller, Paul A.; Dhamne, Sameer C.; Vahabzadeh-Hagh, Andrew M.; Pascual-Leone, Alvaro; Jensen, Frances E.; Rotenberg, Alexander (Public Library of Science, 2014)
      Repetitive transcranial magnetic stimulation (rTMS) is a widely-used method for modulating cortical excitability in humans, by mechanisms thought to involve use-dependent synaptic plasticity. For example, when low frequency ...
    • Temporal Lobe Cortical Electrical Stimulation during the Encoding and Retrieval Phase Reduces False Memories 

      Boggio, Paulo S.; Fregni, Felipe; Valasek, Claudia; Ellwood, Sophie; Chi, Richard Po-Hung; Gallate, Jason; Pascual-Leone, Alvaro; Snyder, Allan (Public Library of Science, 2009)
      A recent study found that false memories were reduced by 36% when low frequency repetitive transcranial magnetic stimulation (rTMS) was applied to the left anterior temporal lobe after the encoding (study) phase. Here we ...
    • TMS affects moral judgment, showing the role of DLPFC and TPJ in cognitive and emotional processing 

      Jeurissen, Danique; Sack, Alexander T.; Roebroeck, Alard; Russ, Brian E.; Pascual-Leone, Alvaro (Frontiers Media S.A., 2014)
      Decision-making involves a complex interplay of emotional responses and reasoning processes. In this study, we use TMS to explore the neurobiological substrates of moral decisions in humans. To examining the effects of TMS ...
    • Transcranial magnetic stimulation coregistered with MRI: a comparison of a guided versus blind stimulation technique and its effect on evoked compound muscle action potentials 

      Gugino, Laverne Dennis; Rafael Romero, J; Aglio, Linda Susan; Titone, Debra; Ramirez, Marcela; Pascual-Leone, Alvaro; Grimson, Eric; Weisenfeld, Neil; Kikinis, Ron; Shenton, Martha Elizabeth (Elsevier BV, 2001)
      Introduction and methods: Compound muscle action potentials (CMAPs) elicited by transcranial magnetic stimulation (TMS) are characterized by enormous variability, even when attempts are made to stimulate the same scalp ...
    • Transcranial magnetic stimulation of the brain: guidelines for pain treatment research 

      Klein, Max M.; Treister, Roi; Raij, Tommi; Pascual-Leone, Alvaro; Park, Lawrence; Nurmikko, Turo; Lenz, Fred; Lefaucheur, Jean-Pascal; Lang, Magdalena; Hallett, Mark; Fox, Michael; Cudkowicz, Merit; Costello, Ann; Carr, Daniel B.; Ayache, Samar S.; Oaklander, Anne Louise (Wolters Kluwer, 2015)
      Abstract Recognizing that electrically stimulating the motor cortex could relieve chronic pain sparked development of noninvasive technologies. In transcranial magnetic stimulation (TMS), electromagnetic coils held against ...
    • Typical Neural Representations of Action Verbs Develop without Vision 

      Bedny, Marina; Caramazza, Alfonso; Pascual-Leone, Alvaro; Saxe, Rebecca (Oxford University Press (OUP), 2011)
      Many empiricist theories hold that concepts are composed of sensory–motor primitives. For example, the meaning of the word “run” is in part a visual image of running. If action concepts are partly visual, then the concepts ...
    • Use of Transcranial Magnetic Stimulation in Autism Spectrum Disorders 

      Oberman, Lindsay M.; Rotenberg, Alexander; Pascual-Leone, Alvaro (Springer Science + Business Media, 2013)
      The clinical, social and financial burden of autism spectrum disorder (ASD) is staggering. We urgently need valid and reliable biomarkers for diagnosis and effective treatments targeting the often debilitating symptoms. ...
    • Using Non-invasive Brain Stimulation to Augment Motor Training-induced Plasticity 

      Bolognini, Nadia; Pascual-Leone, Alvaro; Fregni, Felipe (BioMed Central, 2009)
      Therapies for motor recovery after stroke or traumatic brain injury are still not satisfactory. To date the best approach seems to be the intensive physical therapy. However the results are limited and functional gains are ...