Browsing by Author "Whitesides, George"

Now showing items 41-60 of 214

    • Defining the Value of Injection Current and Effective Electrical Contact Area for EGaIn-Based Molecular Tunneling Junctions 

      Simeone, Felice Carlo; Yoon, Hyo Jae; Thuo, Martin M.; Barber, Jabulani Randall; Smith, Barbara; Whitesides, George McClelland (American Chemical Society, 2013)
      Analysis of rates of tunneling across self-assembled monolayers (SAMs) of n-alkanethiolates SCn (with n = number of carbon atoms) incorporated in junctions having structure AgTS-SAM//Ga2O3/EGaIn leads to a value for the ...

    • Denaturation of Proteins by SDS and Tetraalkylammonium Dodecyl Sulfates 

      Lee, Andrew; Tang, Sindy K. Y.; Mace, Charles R.; Whitesides, George McClelland (American Chemical Society (ACS), 2011)
      This article describes the use of capillary electrophoresis (CE) to examine the influence of different cations (C(+); C(+) = Na(+) and tetra-n-alkylammonium, NR(4)(+), where R = Me, Et, Pr, and Bu) on the rates of denaturation ...

    • Density-based separation in multiphase systems provides a simple method to identify sickle cell disease 

      Kumar, A. A.; Patton, Matthew Reiser; Hennek, J. W.; Lee, S. Y. R.; D, G.; Yang, X.; Kanter, J.; Shevkoplyas, S. S.; Brugnara, Carlo; Whitesides, George McClelland (Proceedings of the National Academy of Sciences, 2014)
      Although effective low-cost interventions exist, child mortality attributable to sickle cell disease (SCD) remains high in low-resource areas due, in large part, to the lack of accessible diagnostic methods. The presence ...

    • Density-Based Separations in Aqueous Multiphase Systems: Tools for Biological Research and Low-Cost Diagnostics 

      Kumar, Ashok Ashwin (2014-06-06)
      Cells often exist in heterogeneous mixtures. Density provides a property to separate several types of cells from the mixed sample in which they originate. Density-based separation methods provide a standard method to ...

    • Dependence of Avidity on Linker Length for a Bivalent Ligand–Bivalent Receptor Model System 

      Mack, Eric T.; Snyder, Phillip W.; Perez-Castillejos, Raquel; Bilgiçer, Başar; Moustakas, Demetri T.; Butte, Manish J.; Whitesides, George M. (American Chemical Society, 2012)
      This paper describes a synthetic dimer of carbonic anhydrase, and a series of bivalent sulfonamide ligands with different lengths (25 to 69 Å between the ends of the fully extended ligands), as a model system to use in ...

    • The Determination of the Location of Contact Electrification-Induced Discharge Events 

      Vella, Sarah J.; Chen, Xin; Thomas, Samuel W. III; Zhao, Xuanhe; Suo, Zhigang; Whitesides, George M. (American Chemical Society, 2010)
      This paper describes a method for determining the location of contact electrification-induced electrical discharges detected in a system comprising a steel sphere rolling in a circular path on an organic insulator. The ...

    • The development of bioresorbable composite polymeric implants with high mechanical strength 

      Sharma, Upma; Concagh, Danny; Core, Lee; Kuang, Yina; You, Changcheng; Pham, Quynh; Zugates, Greg; Busold, Rany; Webber, Stephanie; Merlo, Jonathan; Langer, Robert S.; Whitesides, George McClelland; Palasis, Maria (Springer Nature, 2017)

    • Diagnosis of iron deficiency anemia using density-based fractionation of red blood cells 

      Hennek, Jonathan; Kumar, Ashok Ashwin; Wiltschko, Alexander Bame; Patton, Matthew Reiser; Lee, Si Yi Ryan; Brugnara, Carlo; Adams, Ryan Prescott; Whitesides, George McClelland (Royal Society of Chemistry (RSC), 2016)
      Iron deficiency anemia (IDA) is a nutritional disorder that impacts over one billion people worldwide, it causes permanent cognitive impairment in children, fatigue in adults, and suboptimal outcomes in pregnancy. IDA can ...

    • Disulfide-Based Diblock Copolymer Worm Gels: A Wholly-Synthetic Thermoreversible 3D Matrix for Sheet-Based Cultures 

      Simon, Karen Alambra; Warren, Nicholas J.; Mosadegh, Bobak; Mohammady, Marym R.; Whitesides, George McClelland; Armes, Steven P. (American Chemical Society (ACS), 2015)
      It is well-known that 3D in vitro cell cultures provide a much better model than 2D cell cultures for understanding the in vivo microenvironment of cells. However, significant technical challenges in handling and analyzing ...

    • Effect of Surfactant Hydrophobicity on the Pathway for Unfolding of Ubiquitin 

      Shaw, Bryan F.; Schneider, Grégory F.; Whitesides, George M. (American Chemical Society (ACS), 2012)
      This paper describes the interaction between ubiquitin (UBI) and three sodium n-alkyl sulfates (SCnS) that have the same charge (Z = −1) but different hydrophobicity (n = 10, 12, or 14). Increasing the hydrophobicity of ...

    • Elastomeric Origami: Programmable Paper-Elastomer Composites as Pneumatic Actuators 

      Martinez, Ramses Valentin; Fish, Carina Raquel; Chen, Xin; Whitesides, George M. (Wiley-VCH Verlag Berlin, 2012)
      The development of soft pneumatic actuators based on composites consisting of elastomers with embedded sheet or fiber structures (e.g., paper or fabric) that are flexible but not extensible is described. On pneumatic ...

    • Elastomeric Tiles for the Fabrication of Inflatable Structures 

      Morin, Stephen A.; Kwok, Sen Wai; Lessing, Joshua; Ting, Jason; Shepherd, Robert F.; Stokes, Adam A.; Whitesides, George McClelland (Wiley-Blackwell, 2014)
      This paper describes the fabrication of 3D soft, inflatable structures from thin, 2D tiles fabricated from elastomeric polymers. The tiles are connected using soft joints that increase the surface area available for gluing ...

    • Electric winds driven by time oscillating corona discharges 

      Drews, Aaron M.; Cademartiri, Ludovico; Whitesides, George McClelland; Bishop, Kyle J. M. (American Institute of Physics, 2013)
      We investigate the formation of steady gas flows—so-called electric winds—created by point-plane corona discharges driven by time oscillating (ac) electric fields. By varying the magnitude and frequency of the applied ...

    • The Electrical Resistance of AgTS-S(CH2)n-1CH3//Ga2O3/EGaIn Tunneling Junctions 

      Cademartiri, Ludovico; Thuo, Martin M.; Nijhuis, Christian A.; Reus, William F.; Tricard, Simon; Barber, Jabulani Randall; Sodhi, Rana N. S.; Brodersen, Peter; Kim, Choongik; Chiechi, Ryan C.; Whitesides, George M. (American Chemical Society (ACS), 2012)
      Tunneling junctions having the structure AgTS–S(CH2)n−1CH3//Ga2O3/EGaIn allow physical–organic studies of charge transport across self-assembled monolayers (SAMs). In ambient conditions, the surface of the liquid metal ...

    • Electrical Textile Valves for Paper Microfluidics 

      Ainla, Alar; Hamedi, Mahiar M.; Güder, Firat; Whitesides, George McClelland (Wiley-Blackwell, 2017)
      This paper describes electrically-activated fluidic valves that operate based on electrowetting through textiles. The valves are fabricated from electrically conductive, insulated, hydrophobic textiles, but the concept can ...

    • Electrically Activated Paper Actuators 

      Hamedi, Mahiar; Campbell, Victoria; Rothemund, Philipp Josef Michael; Guder, Firat; Christodouleas, Dionysios; Bloch, Jean-Francis; Whitesides, George McClelland (Wiley-Blackwell, 2016)
      This paper describes the design and fabrication of electrically controlled paper actuators that operate based on the dimensional changes that occur in paper when the moisture absorbed on the surface of the cellulose fibers ...

    • Electroanalytical devices with pins and thread 

      Glavan, Ana C; Ainla, Alar; Hamedi, Mahiar Max; Fernández-Abedul, M. Teresa; Whitesides, George McClelland (Royal Society of Chemistry (RSC), 2016)
      This work describes the adaptive use of conventional stainless steel pins—used in unmodified form or coated with carbon paste—as working, counter, and quasi-reference electrodes in electrochemical devices fabricated using ...

    • Electrochemical Sensing in Paper-Based Microfluidic Devices 

      Nie, Zhihong; Nijhuis, Christian A.; Gong, Jinlong; Chen, Xin; Kumachev, Alexander; Martinez, Andres W.; Narovlyansky, Max; Whitesides, George McClelland (Royal Society of Chemistry, 2010)
      This paper describes the fabrication and the performance of microfluidic paper-based electrochemical sensing devices (we call the microfluidic paper-based electrochemical devices, µPEDs). The µPEDs comprise paper-based ...

    • Emergence of reconfigurable wires and spinners via dynamic self-assembly 

      Kokot, Gasper; Piet, David; Whitesides, George M.; Aranson, Igor S.; Snezhko, Alexey (Nature Publishing Group, 2015)
      Dissipative colloidal materials use energy to generate and maintain structural complexity. The energy injection rate, and properties of the environment are important control parameters that influence the outcome of dynamic ...

    • Engineering Shadows to Fabricate Optical Metasurfaces 

      Nemiroski, Alex; Gonidec, Mathieu; Fox, Jerome Michael; Jean-Remy, Philip; Turnage, Evan; Whitesides, George McClelland (American Chemical Society (ACS), 2014)
      Optical metasurfaces—patterned arrays of plasmonic nanoantennas that enable the precise manipulation of light–matter interactions—are emerging as critical components in many nanophotonic materials, including planar ...