Now showing items 603-622 of 52701

    • Abdominal Cross-sectional Imaging for Inpatients With Abnormal Liver Function Test Results 

      Rothschild, Jeffrey Mark; Khorasani, Ramin; Silverman, Stuart George; Hanson, Richard; Fiskio, Julie M.; Bates, David Westfall (American Medical Association (AMA), 2001)
      Background: Abdominal cross-sectional imaging is often performed to evaluate abnormal liver function test (LFT) results in hospitalized patients. However, few data are available regarding the yield and usefulness of imaging ...
    • Abdominal obesity and hyperglycemia mask the effect of a common APOC3 haplotype on the risk of myocardial infarction 

      Ruiz-Narváez, Edward; Sacks, Frank Martin; Campos, Hannia (American Society for Nutrition, 2008)
      Background Plasma apolipoprotein (apo) C-III strongly predicts myocardial infarction (MI) and directly activates atherogenic processes invascularcells.Geneticvariationintheinsulinresponseelementofthe APOC3 promoter is ...
    • Abdominal Pain, the Adolescent and Altered Brain Structure and Function 

      Hubbard, Catherine S.; Becerra, Lino; Heinz, Nicole; Ludwick, Allison; Rasooly, Tali; Wu, Rina; Johnson, Adriana; Schechter, Neil L.; Borsook, David; Nurko, Samuel (Public Library of Science, 2016)
      Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder of unknown etiology. Although relatively common in children, how this condition affects brain structure and function in a pediatric population ...
    • Abdominal Subcutaneous Adipose Tissue: A Protective Fat Depot? 

      Porter, Stacy Ann; Massaro, Joseph M.; Hoffmann, Udo; Vasan, Ramachandran S.; O'Donnel, Christopher J.; Fox, Caroline (American Diabetes Association, 2009)
      OBJECTIVE: Obesity is associated with increased metabolic and cardiovascular risk. The ectopic fat hypothesis suggests that subcutaneous fat may be protective, but this theory has yet to be fully explored. RESEARCH DESIGN ...
    • Abdominal Superficial Subcutaneous Fat 

      Golan, Rachel; Shelef, Ilan; Rudich, Assaf; Gepner, Yftach; Shemesh, Elad; Chassidim, Yoash; Harman-Boehm, Ilana; Henkin, Yaakov; Schwarzfuchs, Dan; Ben Avraham, Sivan; Witkow, Shula; Liberty, Idit F.; Tangi-Rosental, Osnat; Sarusi, Benjamin; Stampfer, Meir; Shai, Iris (American Diabetes Association, 2012)
      OBJECTIVE: Unlike visceral adipose tissue (VAT), the association between subcutaneous adipose tissue (SAT) and obesity-related morbidity is controversial. In patients with type 2 diabetes, we assessed whether this variability ...
    • Abdominal Superficial Subcutaneous Fat: A putative distinct protective fat subdepot in type 2 diabetes 

      Golan, Rachel; Shelef, Ilan; Rudich, Assaf; Gepner, Yftach; Shemesh, Elad; Chassidim, Yoash; Harman-Boehm, Ilana; Henkin, Yaakov; Schwarzfuchs, Dan; Avraham, Sivan Ben; Witkow, Shula; Liberty, Idit; Tangi-Rosental, Osnat; Sarusi, Benjamin; Stampfer, Meir; Shai, Iris (American Diabetes Association, 2012)
      OBJECTIVE- Unlike visceral adipose tissue (VAT), the association between subcutaneous adipose tissue (SAT) and obesity-related morbidity is controversial. In patients with type 2 diabetes, we assessed whether this variability ...
    • Abe Chayes: A Man Without Boundaries 

      Alford, William P. (2001)
    • Abelson Phosphorylation of CLASP2 Modulates its Association With Microtubules and Actin 

      Engel, Ulrike; Zhan, Yougen; Long, Jennifer B; Boyle, Scott N; Ballif, Bryan A; Dorey, Karel; Gygi, Steven P; Koleske, Anthony J; VanVactor, David (Blackwell Publishing Ltd, 2014)
      The Abelson (Abl) non-receptor tyrosine kinase regulates the cytoskeleton during multiple stages of neural development, from neurulation, to the articulation of axons and dendrites, to synapse formation and maintenance. ...
    • The Abenomics Difference: Three Arrows of Roosevelt Resolve in Japan 

      Choi, Peter (2016-03-07)
      This study investigates Japanese Prime Minister Shinzo Abe’s economic policy package, known as “Abenomics.” Abenomics is intended to end two decades of deflation in Japan, based on a Three Arrow approach (monetary policy, ...
    • Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β 

      Kim, Man Lyang; Chae, Jae Jin; Park, Yong Hwan; De Nardo, Dominic; Stirzaker, Roslynn A.; Ko, Hyun-Ja; Tye, Hazel; Cengia, Louise; DiRago, Ladina; Metcalf, Donald; Roberts, Andrew W.; Kastner, Daniel L.; Lew, Andrew M.; Lyras, Dena; Kile, Benjamin T.; Croker, Ben A.; Masters, Seth L. (The Rockefeller University Press, 2015)
      Gain-of-function mutations that activate the innate immune system can cause systemic autoinflammatory diseases associated with increased IL-1β production. This cytokine is activated identically to IL-18 by an intracellular ...
    • Aberrant Brain Plasticity in Autism Spectrum Disorders 

      Oberman, Lindsay M.; Rotenberg, Alexander; Pascual-Leone, Alvaro (Oxford University Press, 2014)
      Plasticity enables the human brain to adapt to developmental challenges and rapidly changing environmental demands, acquire new skills, and cope with injury. However, aberrant or mistimed brain plasticity can lead to ...
    • Aberrant Cytoplasmic Expression of P63 and Prostate Cancer Mortality 

      Dhillon, Preet K.; Barry, Marc; Stampfer, Meir; Perner, Sven; Fiorentino, Michelangelo; Fornari, Alessandro; Ma, Jing; Fleet, Julia; Kurth, Tobias; Rubin, Mark A.; Mucci, Lorelei A. (American Association for Cancer Research, 2009)
      Protein expression of p63 is used to differentiate prostate cancer from benign mimickers. Recent studies suggest that it may also distinguish aggressive prostate cancer with down-regulated expression occurring in men with ...
    • Aberrant error processing in relation to symptom severity in obsessive–compulsive disorder: A multimodal neuroimaging study 

      Agam, Yigal; Greenberg, Jennifer L.; Isom, Marlisa; Falkenstein, Martha J.; Jenike, Eric; Wilhelm, Sabine; Manoach, Dara S. (Elsevier, 2014)
      Background: Obsessive–compulsive disorder (OCD) is characterized by maladaptive repetitive behaviors that persist despite feedback. Using multimodal neuroimaging, we tested the hypothesis that this behavioral rigidity ...
    • Aberrant Expression of Functional BAFF-System Receptors by Malignant B-Cell Precursors Impacts Leukemia Cell Survival 

      Maia, Sara; Pelletier, Marc; Ding, Jixin; Hsu, Yen-Ming; Sallan, Stephen Earl; Rao, Sambasiva P.; Nadler, Lee Marshall; Cardoso, Angelo A. (Public Library of Science, 2011)
      Despite exhibiting oncogenic events, patient's leukemia cells are responsive and dependent on signals from their malignant bone marrow (BM) microenvironment, which modulate their survival, cell cycle progression, trafficking ...
    • Aberrant islet unfolded protein response in type 2 diabetes 

      Engin, Feyza; Nguyen, Truc; Yermalovich, Alena; Hotamisligil, Gökhan S. (Nature Publishing Group, 2014)
      The endoplasmic reticulum adapts to fluctuations in demand and copes with stress through an adaptive signaling cascade called the unfolded protein response (UPR). Accumulating evidence indicates that the canonical UPR is ...
    • Aberrant microRNA Expression in Spinal Muscular Atrophy Motor Neurons 

      Wertz, Mary Helene (2015-05-18)
      Spinal Muscular Atrophy (SMA) is a devastating autosomal-recessive pediatric neurodegenerative disease characterized by loss of spinal motor neurons. It is caused by mutation in the survival of motor neuron 1, SMN1, gene ...
    • Aberrant regulation of FBW7 in cancer 

      Wang, Lixia; Ye, Xiantao; Liu, Yueyong; Wei, Wenyi; Wang, Zhiwei (Impact Journals LLC, 2014)
      FBW7 (F-box and WD repeat domain-containing 7) or Fbxw7 is a tumor suppressor, which promotes the ubiquitination and subsequent degradation of numerous oncoproteins including Mcl-1, Cyclin E, Notch, c- Jun, and c-Myc. In ...
    • Aberrant semantic activation in schizophrenia: a neurophysiological study 

      Nestor, PG; Kimble, MO; O'Donnell, BF; Smith, L; Niznikiewicz, Margaret A.; Shenton, Martha Elizabeth; McCarley, RW (American Psychiatric Publishing, 1997)
      OBJECTIVE: Schizophrenia has long been thought to be characterized by a fundamental disturbance in semantic associations, which has often been presumed to be of neurobiological origin. The authors examined the neurophysiological ...
    • Aberration in DNA Methylation in B-Cell Lymphomas Has a Complex Origin and Increases with Disease Severity 

      De, Subhajyoti; Shaknovich, Rita; Riester, Markus; Elemento, Olivier; Geng, Huimin; Kormaksson, Matthias; Jiang, Yanwen; Woolcock, Bruce; Johnson, Nathalie; Polo, Jose M.; Cerchietti, Leandro; Gascoyne, Randy D.; Melnick, Ari; Michor, Franziska L. (Public Library of Science, 2013)
      Despite mounting evidence that epigenetic abnormalities play a key role in cancer biology, their contributions to the malignant phenotype remain poorly understood. Here we studied genome-wide DNA methylation in normal ...
    • Aberration-Free Ultrathin Flat Lenses and Axicons at Telecom Wavelengths Based on Plasmonic Metasurfaces 

      Aieta, Francesco; Genevet, Patrice; Kats, Mikhail A.; Yu, Nanfang; Blanchard, Romain; Gaburro, Zeno; Capasso, Federico (American Chemical Society, 2012)
      The concept of optical phase discontinuities is applied to the design and demonstration of aberration-free planar lenses and axicons, comprising a phased array of ultrathin subwavelength-spaced optical antennas. The lenses ...