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Defending the Refutation of Idealism
(Southwestern Philosophical Society, 2000)In his Kant and the Claims of Knowledge, Paul Guyer offers an influential reading of Kant’s famous “Refutation of Idealism.” Guyer’s reading has been widely praised as Kantian exegesis but less favorably received as an ... -
Defending “Something Special”: A Portrait of One School’s Response to Instability
(2014-11-06)Drawing primarily on interviews with a variety of teachers and other staff at a large urban Title-1 public school in California, Victoria Theisen-Homer paints an ethnographic portrait of how school personnel respond to ... -
A Defense of Traditional Hypotheses about the Term Structure of Interest Rates
(Blackwell Publishing, 1986)Expectations theories of asset returns may be interpreted either as stating that risk premia are zero or that they are constant through time. Under the former interpretation, different versions of the expectations theory ... -
A Defensin from the Model Beetle Tribolium castaneum Acts Synergistically with Telavancin and Daptomycin against Multidrug Resistant Staphylococcus aureus
(Public Library of Science, 2015)The red flour beetle Tribolium castaneum is a common insect pest and has been established as a model beetle to study insect development and immunity. This study demonstrates that defensin 1 from T. castaneum displays in ... -
Defensive Localism: A View of the Field from the Field
(The University of Virginia, 2005) -
Deference and Due Process
(2015)In the textbooks, procedural due process is a strictly judicial enterprise; although substantive entitlements are created by legislative and executive action, it is for courts to decide independently what process the ... -
Deferred Acceptance Algorithms: History, Theory, Practice, and Open Questions
(Springer, 2008)The deferred acceptance algorithm proposed by Gale and Shapley (1962) has had a profound influence on market design, both directly, by being adapted into practical matching mechanisms, and, indirectly, by raising new ... -
Deferred Compensation Revisited
(Tax Analysts and Advocates, 2007)The tax rules governing deferred compensation, codified at section 409A, are harsh and complex. The rules are focused on the least important policy considerations and overlook the most important. Professors Halperin and ... -
Defiance, Insubordination, and Disrespect: Perceptions of Power in Middle School Discipline
(2015-05-15)Defiance, insubordination, and disrespect (together, “DID”) are the most common disciplinary infractions in U.S. secondary schools (Gregory & Weinstein, 2008). Consequences for these infractions -- challenges to the power ... -
Deficiency of cathepsin S reduces atherosclerosis in LDL receptor–deficient mice
(American Society for Clinical Investigation, 2003)Human atherosclerotic lesions overexpress the lysosomal cysteine protease cathepsin S (Cat S), one of the most potent mammalian elastases known. In contrast, atheromata have low levels of the endogenous Cat S inhibitor ... -
Deficiency of Lipid Phosphatase SHIP Enables Long-Term Reconstitution of Hematopoietic Inductive Bone Marrow Microenvironment
(Elsevier BV, 2013)A dysfunctional bone marrow (BM) microenvironment is thought to contribute to the development of hematologic diseases. However, functional replacement of pathologic BM microenvironment through BM transplantation has not ... -
Deficiency of Phosphoinositide 3-Kinase Enhancer Protects Mice From Diet-Induced Obesity and Insulin Resistance
(American Diabetes Association, 2010)OBJECTIVE: Phosphoinositide 3-kinase enhancer A (PIKE-A) is a proto-oncogene that promotes tumor growth and transformation by enhancing Akt activity. However, the physiological functions of PIKE-A in peripheral tissues are ... -
Deficiency of Retinaldehyde Dehydrogenase 1 Induces BMP2 and Increases Bone Mass In Vivo
(Public Library of Science, 2013)The effects of retinoids, the structural derivatives of vitamin A (retinol), on post-natal peak bone density acquisition and skeletal remodeling are complex and compartment specific. Emerging data indicates that retinoids, ... -
Deficient biological motion perception in schizophrenia: results from a motion noise paradigm
(Frontiers Media S.A., 2013)Background:: Schizophrenia patients exhibit deficient processing of perceptual and cognitive information. However, it is not well-understood how basic perceptual deficits contribute to higher level cognitive problems in ... -
Deficient Heads and Long Head Movement in Slovak
(Michigan Slavic Publications, 1997)This paper examines verbal clitics in Polish and Slovak -
Deficits in High- (>60 Hz) Gamma-Band Oscillations During Visual Processing in Schizophrenia
(Frontiers Media S.A., 2013)Current theories of the pathophysiology of schizophrenia have focused on abnormal temporal coordination of neural activity. Oscillations in the gamma-band range (>25 Hz) are of particular interest as they establish ... -
A defined network of fast-spiking interneurons in orbitofrontal cortex: responses to behavioral contingencies and ketamine administration
(Frontiers Media SA, 2009)Orbitofrontal cortex (OFC) is a region of prefrontal cortex implicated in the motivational control of behavior and in related abnormalities seen in psychosis and depression. It has been hypothesized that a critical mechanism ... -
A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays
(2016)Cardiomyocytes from human stem cells have applications in regenerative medicine and can provide models for heart disease and toxicity screening. Soluble components of the culture system such as growth factors within serum ... -
Defining a Radiomic Response Phenotype: A Pilot Study using targeted therapy in NSCLC
(Nature Publishing Group, 2016)Medical imaging plays a fundamental role in oncology and drug development, by providing a non-invasive method to visualize tumor phenotype. Radiomics can quantify this phenotype comprehensively by applying image-characterization ... -
Defining a Role for T Regulatory Cell Expressed MyD88 During the Response to Allografts
(2015-11-16)The myeloid differentiation primary response gene 88 (MyD88) is an adaptor protein proximally downstream of the Toll-like receptor (TLRs) and the IL-1 receptor family (IL-1R, IL- 18R and IL-33R). The TLR-MyD88 signaling ...