Now showing items 56515-56534 of 56596

    • Zalmoxidae (Arachnida: Opiliones: Laniatores) of the Paleotropics: a catalogue of Southeast Asian and Indo-Pacific species 

      Sharma, Prashant Pradeep; Kury, Adriano B.; Giribet, Gonzalo (Magnolia Press, 2011)
      A revised catalogue of the Paleotropical Zalmoxidae including images of selected available type specimens is presented. Distribution data are provided to the best of our knowledge. The genera Acrozalmoxis Roewer, 1915, ...
    • ZBED6 Modulates the Transcription of Myogenic Genes in Mouse Myoblast Cells 

      Jiang, Lin; Wallerman, Ola; Younis, Shady; Rubin, Carl-Johan; Gilbert, Elizabeth R.; Sundström, Elisabeth; Ghazal, Awaisa; Zhang, Xiaolan; Wang, Li; Mikkelsen, Tarjei S.; Andersson, Göran; Andersson, Leif (Public Library of Science, 2014)
      ZBED6 is a recently discovered transcription factor, unique to placental mammals, that has evolved from a domesticated DNA transposon. It acts as a repressor at the IGF2 locus. Here we show that ZBED6 acts as a transcriptional ...
    • ZBTB20 is required for anterior pituitary development and lactotrope specification 

      Cao, Dongmei; Ma, Xianhua; Cai, Jiao; Luan, Jing; Liu, An-Jun; Yang, Rui; Cao, Yi; Zhu, Xiaotong; Zhang, Hai; Chen, Yu-Xia; Shi, Yuguang; Shi, Guang-Xia; Zou, Dajin; Cao, Xuetao; Grusby, Michael J.; Xie, Zhifang; Zhang, Weiping J. (Nature Publishing Group, 2016)
      The anterior pituitary harbours five distinct hormone-producing cell types, and their cellular differentiation is a highly regulated and coordinated process. Here we show that ZBTB20 is essential for anterior pituitary ...
    • Zcchc11 Uridylates Mature miRNAs to Enhance Neonatal IGF-1 Expression, Growth, and Survival 

      Jones, Matthew R.; Blahna, Matthew T.; Kozlowski, Elyse; Matsuura, Kori Y.; Ferrari, Joseph D.; Morris, Samantha A; Powers, John T; Daley, George Quentin; Quinton, Lee J.; Mizgerd, Joseph P. (Public Library of Science, 2012)
      The Zcchc11 enzyme is implicated in microRNA (miRNA) regulation. It can uridylate let-7 precursors to decrease quantities of the mature miRNA in embryonic stem cell lines, suggested to mediate stem cell maintenance. It can ...
    • ZDHHC7-Mediated S-Palmitoylation of Scribble Regulates Cell Polarity 

      Chen, Baoen; Zheng, Baohui; DeRan, Micael; Jarugumilli, Gopala K.; Fu, Jianjun; Brooks, Yang S.; Wu, Xu (2016)
      Scribble (SCRIB) is a tumor suppressor protein, playing critical roles in establishing and maintaining epithelial cell polarity. Paradoxically, SCRIB is frequently amplified in human cancers, however, fails to localize ...
    • Zebrafish behavioral profiling identifies multi-target antipsychotic-like compounds 

      Bruni, Giancarlo; Rennekamp, Andrew J.; Velenich, Andrea; McCarroll, Matthew; Gendelev, Leo; Fertsch, Ethan; Taylor, Jack; Lakhani, Parth; Lensen, Dennis; Evron, Tama; Lorello, Paul J.; Huang, Xi-Ping; Kolczewski, Sabine; Carey, Galen; Caldarone, Barbara J.; Prinssen, Eric; Roth, Bryan L.; Keiser, Michael J.; Peterson, Randall T.; Kokel, David (2016)
      Many psychiatric drugs act on multiple targets and therefore require screening assays that encompass a wide target space. With sufficiently rich phenotyping, and a large sampling of compounds, it should be possible to ...
    • Zebrafish Globin Switching Occurs in Two Developmental Stages and Is Controlled by the LCR 

      Ganis, Jared Jason; Hsia, Nelson; Trompouki, Eirini; de Jong, Jill L.O.; DiBiase, Anthony; Lambert, Janelle S.; Jia, Zhiying; Sabo, Peter J.; Weaver, Molly; Sandstrom, Richard; Stamatoyannopoulos, John A.; Zhou, Yi; Zon, Leonard Ira (Elsevier BV, 2012)
      Globin gene switching is a complex, highly regulated process allowing expression of distinct globin genes at specific developmental stages. Here, for the first time, we have characterized all of the zebrafish globins based ...
    • Zebrafish Immune Cell Development and Diversity in Health and Disease 

      Rubin, Sara Ann (2022-06-06)
      Hematopoiesis, the process by which all blood cells are generated, is directed by transcription factors and signaling pathways that are highly conserved between zebrafish and humans. In healthy individuals, hematopoietic ...
    • A zebrafish model of conditional targeted podocyte ablation and regeneration 

      Huang, Jianmin; Mckee, Mary; Huang, Hong Dong; Xiang, Alice; Davidson, Alan J; Lu, Hua A J (2013)
      Podocytes are specialized cells that contribute critically to the normal structure and function of the glomerular filtration barrier. Their depletion plays an important role in the pathogenesis of glomerulosclerosis. Here, ...
    • A Zebrafish Model of Uveal Melanoma 

      Rose, Kristin (2015-05-06)
      Uveal melanoma is the most common primary intraocular tumor in adults, and is often characterized by poor prognosis and few effective therapeutic options. The typical site of metastasis for uveal melanoma is the liver, and ...
    • Zebrafish models of cerebrovascular disease 

      Walcott, Brian P; Peterson, Randall T (Nature Publishing Group, 2014)
      Perturbations in cerebral blood flow and abnormalities in blood vessel structure are the hallmarks of cerebrovascular disease. While there are many genetic and environmental factors that affect these entities through a ...
    • Zebrafish Models of Congenital Myopathy 

      Smith, Laura Lindsay (2015-08-31)
      The congenital myopathies are a diverse group of inherited neuromuscular disorders that manifest as skeletal muscle weakness at birth or in infancy, and are classically defined by the predominant morphological features ...
    • Zebrafish Neurobiology: From Development to Circuit Function and Behaviour 

      Engert, Florian; Wilson, Steve (Wiley Blackwell (John Wiley & Sons), 2012)
    • Zebrafish orthologs of human muscular dystrophy genes 

      Steffen, Leta S; Guyon, Jeffrey R; Vogel, Emily D; Beltre, Rosanna; Pusack, Timothy J; Zhou, Yi; Zon, Leonard Ira; Kunkel, Louis Martens (BioMed Central, 2007)
      Background: Human muscular dystrophies are a heterogeneous group of genetic disorders which cause decreased muscle strength and often result in premature death. There is no known cure for muscular dystrophy, nor have all ...
    • Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis 

      Storer, Narie Y.; White, Richard M.; Uong, Audrey; Price, Emily; Nielsen, G. Petur; Langenau, David M.; Zon, Leonard I. (Company of Biologists, 2013)
      Rhabdomyosarcoma is a pediatric malignancy thought to arise from the uncontrolled proliferation of myogenic cells. Here, we have generated models of rhabdomyosarcoma in the zebrafish by inducing oncogenic KRAS(G12D) ...
    • Zebrafish VEGF Receptors: A Guideline to Nomenclature 

      Bussmann, Jeroen; Lawson, Nathan; Zon, Leonard Ira; Schulte-Merker, Stefan; Zebrafish Nomenclature Committee (Public Library of Science, 2008)
    • zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish 

      Chen, Chen-Hui; Durand, Ellen; Wang, Jinhu; Zon, Leonard I.; Poss, Kenneth D. (Company of Biologists, 2013)
      The zebrafish has become a standard model system for stem cell and tissue regeneration research, based on powerful genetics, high tissue regenerative capacity and low maintenance costs. Yet, these studies can be challenged ...
    • Zeeman Relaxation of CaF in Low-Temperature Collisions with Helium 

      Maussang, Kenneth; Egorov, Dima; Helton, Joel S.; Nguyen, Scott V.; Doyle, John M. (American Physical Society (APS), 2005)
      The collision-induced Zeeman relaxation rate for collisions of CaF X2Σ (v00 = 0) with 3He is measured to be ΓZ = (7.7 + 5.4/ − 2.5) × 10−15 cm3 /s at 2 K. This rate is a direct measurement of the influence of spin-rotation ...
    • Zeeman Relaxation of Cold Atomic Iron and Nickel in Collisions with \(^3\)He 

      Johnson, Cort; Newman, Bonna; Brahms, Nathan; Doyle, John M.; Kleppner, Daniel; Greytak, Thomas J. (American Physical Society, 2010)
      We have measured the ratio γ of the diffusion cross section to the angular momentum reorientation cross section in the colliding Fe-\(^3\)He and Ni-\(^3\)He systems. Nickel (Ni) and iron (Fe) atoms are introduced via laser ...