Browsing by Title

Now showing items 133-152 of 56863

    • 50-year trends in US socioeconomic inequalities in health: US-born Black and White Americans, 1959–2008 

      Krieger, Nancy; Kosheleva, Anna; Waterman, Pamela; Chen, Jarvis; Beckfield, Jason; Kiang, Mathew V (Oxford University Press (OUP), 2014-03-16)
      Background: Debates exist over whether health inequities are bound to rise as population health improves, due to health improving more quickly among the better off, with most analyses focused on mortality data. Methods: ...

    • 52-kDa Ro/SSA Epitopes Preferentially Recognized by Antibodies from Mothers of Children with Neonatal Lupus and Congenital Heart Block 

      Fritsch, Christine; Hoebeke, Johan; Dali, Hayet; Ricchiuti, Vincent; Isenberg, David A; Meyer, Olivier; Muller, Sylviane (BioMed Central, 2005)
      Neonatal lupus erythematosus is a rare disorder caused by the transplacental passage of maternal autoantibodies. The 52-kDa Ro/SSA antigen (Ro52) ribonucleoprotein represents an antigenic target strongly associated with ...

    • 53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis 

      Morales, Julio C.; Franco, Sonia; Murphy, Michael M.; Bassing, Craig H.; Mills, Kevin D.; Adams, Melissa M.; Walsh, Nicole C.; Manis, John P.; Rassidakis, George Z.; Alt, Frederick W.; Carpenter, Phillip B. (National Academy of Sciences, 2006)
      p53-binding protein 1 (53BP1) participates in the cellular response to DNA double-stranded breaks where it associates with various DNA repair/cell cycle factors including the H2AX histone variant. Mice deficient for 53BP1 ...

    • 53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks 

      Guirouilh-Barbat, Josée; Gelot, Camille; Xie, Anyong; Dardillac, Elodie; Scully, Ralph; Lopez, Bernard S. (Public Library of Science, 2016)
      DNA double-strand breaks (DSB) are very harmful lesions that can generate genome rearrangements. In this study, we used intrachromosomal reporters to compare both the efficiency and accuracy of end-joining occurring with ...

    • 5mC and 5hmC dynamics during PGC reprogramming and role of Tet1 in female meiosis 

      Yamaguchi, Shinpei; Hong, Kwonho; Liu, Rui; Shen, Li; Inoue, Azusa; Diep, Dinh; Zhang, Kun; Zhang, Yi (BioMed Central, 2013)

    • 5α-reductase Inhibitors and Risk of High-grade or Lethal Prostate Cancer 

      Preston, Mark A.; Wilson, Kathryn; Markt, Sarah C.; Ge, Rongbin; Morash, Christopher; Stampfer, Meir; Loda, Massimo F.; Giovannucci, Edward; Mucci, Lorelei A.; Olumi, Aria F. (American Medical Association, 2014)

    • A 600 kb Deletion Syndrome at 16p11.2 Leads to Energy Imbalance and Neuropsychiatric Disorders 

      Zufferey, Flore; Sherr, Elliott H; Beckmann, Noam D; Hanson, Ellen M.; Maillard, Anne M; Hippolyte, Loyse; Macé, Aurélien; Ferrari, Carina; Kutalik, Zoltán; Andrieux, Joris; Aylward, Elizabeth; Barker, Mandy; Bernier, Raphael; Bouquillon, Sonia; Conus, Philippe; Delobel, Bruno; Faucett, W Andrew; Goin-Kochel, Robin P; Grant, Ellen; Harewood, Louise; Hunter, Jill V; Lebon, Sébastien; Ledbetter, David H; Martin, Christa Lese; Männik, Katrin; Martinet, Danielle; Mukherjee, Pratik; Ramocki, Melissa B; Spence, Sarah J; Steinman, Kyle J; Tjernagel, Jennifer; Spiro, John E; Reymond, Alexandre; Beckmann, Jacques S; Chung, Wendy K; Jacquemont, Sébastien (BMJ Publishing Group, 2012)
      Background: The recurrent ∼600 kb 16p11.2 BP4-BP5 deletion is among the most frequent known genetic aetiologies of autism spectrum disorder (ASD) and related neurodevelopmental disorders. Objective: To define the medical, ...

    • A 65 k.y. Time Series From Sediment-Hosted Glasses Reveals Rapid Transitions in Ocean Ridge Magmas 

      Ferguson, David; Li, Yinqi; Langmuir, Charles; Costa, Kassandra; McManus, Jerry; Huybers, Peter; Corbotte, Suzanne (Geological Society of America, 2017)
      Studies of ocean ridge magmatism have been hampered by the difficulty in constructing time-series data over more than a few thousand years. Sediment rapidly covers newly formed ocean crust, and older rocks, even when ...

    • 6d Conformal matter 

      Del Zotto, Michele; Heckman, Jonathan J.; Tomasiello, Alessandro; Vafa, Cumrun (Springer Verlag, 2015)
      A single M5-brane probing G, an ADE-type singularity, leads to a system which has G x G global symmetry and can be viewed as "bifundamental" (C, C) matter. For the AN series, this leads to the usual notion of bifundamental ...

    • 7 Leadership Blind Spots: Adult Development, Emotional Intelligence, and Leadership Effectiveness Among Biotech R&D Leaders 

      Shiner, Michael (2015-05-15)
      In this multiple-case study of 6 mid-level leaders working in biotech R&D--an archetype of a complex, uncertain, turbulent, and, multidisciplinary 21st-Century workplace--I explore the importance and interaction of mental ...

    • 7T MRI of spinal cord injury 

      Cohen-Adad, J.; Zhao, Wei Chen; Wald, Lawrence Leroy; Oaklander, Anne Louise (Ovid Technologies (Wolters Kluwer Health), 2012)
      A man with 25 years of mild left neck, arm, and leg paresthesias had initial MRI in 1996 identifying a left C3-4 dorsal horn cavernous hemangioma. In 1997, hemorrhage (C3-7) and resection induced left arm > leg proprioceptive ...

    • 8.4 GHz VLBI Observations of SN 2004et in NGC 6946 

      Martí-Vidal, I.; Marcaide, J. M.; Alberdi, A.; Guirado, J. C.; Lara, L.; Pérez-Torres, M. A.; Ros, E.; Argo, M. K.; Beswick, R. J.; Muxlow, T. W. B.; Pedlar, A.; Shapiro, Irwin; Stockdale, C. J.; Sramek, R. A.; Weiler, K. W.; Vinko, J. (EDP Sciences, 2007-05-25)
      We report on 8.4 GHz very-long-baseline-interferometry (VLBI) observations of the type II-P supernova SN2004et in the spiral galaxy NGC 6946, made on 20 February 2005 (151 days after explosion). The Very Large Array (VLA) ...

    • 87 Rare Variants Associated With Blood Pressure in Meta-Analysis of ∼1.32 Million Individuals 

      Feofanova, Elena; Franks, Paul (Ovid Technologies (Wolters Kluwer Health), 2021-04)
      Genetic studies of blood pressure (BP) to date have mainly analysed common variants (minor allele frequency, MAF>0.05). In a meta-analysis of up to >1.3 million participants, we discovered 106 new BP-associated genomic ...

    • 89 Zr-Labeled Dextran Nanoparticles Allow in Vivo Macrophage Imaging 

      Keliher, Edmund J.; Yoo, Jeongsoo; Nahrendorf, Matthias; Lewis, Jason S.; Marinelli, Brett; Newton, Andita; Pittet, Mikael J.; Weissleder, Ralph (American Chemical Society, 2011)
      Tissue macrophages play a critical role both in normal physiology and in disease states. However, because of a lack of specific imaging agents, we continue to have a poor understanding of their absolute numbers, flux rates, ...

    • The 8q24 Cancer Risk Variant Rs6983267 Shows Long-Range Interaction With MYC in Colorectal Cancer 

      Pomerantz, Mark; Ahmadiyeh, Nasim; Jia, Li; Herman, Paula; Verzi, Michael; Doddapaneni, Harshavardhan; Beckwith, Christine A.; Chan, Jennifer A.; Hills, Adam; Davis, Matt; Yao, Keluo; Kehoe, Sarah M.; Lenz, Heinz-Josef; Haiman, Christopher A.; Yan, Chunli; Henderson, Brian E.; Frenkel, Baruch; Barretina, Jordi; Bass, Adam; Tabernero, Josep; Baselga, Jose; Regan, Meredith; Manak, J. Robert; Shivdasani, Ramesh; Coetzee, Gerhard A.; Freedman, Matthew (Springer Science and Business Media LLC, 2009-06-28)
      An inherited variant on chromosome 8q24, rs6983267, is significantly associated with cancer pathogenesis. We present evidence that this region is a transcriptional enhancer, that the risk region physically interacts with ...

    • The 8th Annual Computational and Systems Neuroscience (Cosyne) Meeting 

      Histed, Mark; Pillow, Jonathan W (BioMed Central, 2011)

    • 8th international conference on management and rehabilitation of chronic respiratory failure: the long summaries – part 1 

      Ambrosino, Nicolino; Casaburi, Richard; Chetta, Alfredo; Clini, Enrico; Donner, Claudio F.; Dreher, Michael; Goldstein, Roger; Jubran, Amal; Nici, Linda; Owen, Caroline A.; Rochester, Carolyn; Tobin, Martin J.; Vagheggini, Guido; Vitacca, Michele; ZuWallack, Richard (BioMed Central, 2015)
      This paper summarizes the Part 1 of the proceedings of the 8th International Conference on Management and Rehabilitation of Chronic Respiratory Failure, held in Pescara, Italy, on 7 and 8 May, 2015. It summarizes the ...

    • 8th International conference on management and rehabilitation of chronic respiratory failure: the long summaries – part 2 

      Ambrosino, Nicolino; Casaburi, Richard; Chetta, Alfredo; Clini, Enrico; Donner, Claudio F.; Dreher, Michael; Goldstein, Roger; Jubran, Amal; Nici, Linda; Owen, Caroline A.; Rochester, Carolyn; Tobin, Martin J.; Vagheggini, Guido; Vitacca, Michele; ZuWallack, Richard (BioMed Central, 2015)
      This paper summarizes the Part 2 of the proceedings of the 8th International Conference on Management and Rehabilitation of Chronic Respiratory Failure, held in Pescara, Italy, on 7 and 8 May, 2015. It summarizes the ...

    • 8th International conference on management and rehabilitation of chronic respiratory failure: the long summaries – Part 3 

      Ambrosino, Nicolino; Casaburi, Richard; Chetta, Alfredo; Clini, Enrico; Donner, Claudio F.; Dreher, Michael; Goldstein, Roger; Jubran, Amal; Nici, Linda; Owen, Caroline A.; Rochester, Carolyn; Tobin, Martin J.; Vagheggini, Guido; Vitacca, Michele; ZuWallack, Richard (BioMed Central, 2015)
      This paper summarizes the Part 3 of the proceedings of the 8th International Conference on Management and Rehabilitation of Chronic Respiratory Failure, held in Pescara, Italy, on 7 and 8 May, 2015. It summarizes the ...

    • 9-Genes Reinforce the Phylogeny of Holometabola and Yield Alternate Views on the Phylogenetic Placement of Strepsiptera 

      McKenna, Duane D; Farrell, Brian Dorsey (Public Library of Science, 2010)
      Background: The extraordinary morphology, reproductive and developmental biology, and behavioral ecology of twisted wing parasites (order Strepsiptera) have puzzled biologists for centuries. Even today, the phylogenetic ...