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Now showing items 24886-24905 of 56295

    • Impact of Patents on Access to HIV/AIDS Drugs in Developing Countries 

      Borrell, Joan-Ramon; Watal, Jayashree (Center for International Development at Harvard University, 2002-05)
      This paper uses sales data on HIV/AIDS drugs in a sample of 34 low and middle income countries between 1995 and 1999 to assess empirically the impact of patents on unsubsidized access to a new drug therapy. There can be ...

    • Impact of Patient Prescription History on Emergency Department Opioid Prescribing for Acute Pain 

      Sueker, Judah (2015-06-08)
      With prescription opioid abuse having reached epidemic proportions, Emergency Department clinicians must assess the safety of prescribing opioid pain medication to patients for whom they have limited information or history. ...

    • The impact of pediatric blood and marrow transplant on parents: introduction of the parent impact scale 

      Heinze, Katherine E; Rodday, Angie Mae; Nolan, Marie T; Bingen, Kristin; Kupst, Mary Jo; Patel, Sunita K; Syrjala, Karen; Harris, Lynnette; Recklitis, Christopher; Schwartz, Lisa; Davies, Stella; Guinan, Eva C; Noll, Robert; Chang, Grace; Parsons, Susan K (BioMed Central, 2015)
      Background: Parents often experience stress-related complications when their child requires blood and marrow transplant (BMT). Previous studies have described the emotional toll BMT places on parents during the acute phase ...

    • Impact of pharmaceutical policy interventions on utilization of antipsychotic medicines in Finland and Portugal in times of economic recession: interrupted time series analyses 

      Leopold, Christine; Zhang, Fang; Mantel-Teeuwisse, Aukje K; Vogler, Sabine; Valkova, Silvia; Ross-Degnan, Dennis; Wagner, Anita K (BioMed Central, 2014)
      Objectives: To analyze the impacts of pharmaceutical sector policies implemented to contain country spending during the economic recession – a reference price system in Finland and a mix of policies including changes in ...

    • The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum 

      Xu, Wei; Wang, Hui-Fu; Tan, Lin; Tan, Meng-Shan; Tan, Chen-Chen; Zhu, Xi-Chen; Miao, Dan; Yu, Wan-Jiang; Jiang, Teng; Tan, Lan; Yu, Jin-Tai; Weiner, Michael W.; Aisen, Paul; Petersen, Ronald; Jack, Clifford R.; Jagust, William; Trojanowki, John Q.; Toga, Arthur W.; Beckett, Laurel; Green, Robert C.; Saykin, Andrew J.; Morris, John; Shaw, Leslie M.; Kaye, Jeffrey; Quinn, Joseph; Silbert, Lisa; Lind, Betty; Carter, Raina; Dolen, Sara; Schneider, Lon S.; Pawluczyk, Sonia; Beccera, Mauricio; Teodoro, Liberty; Spann, Bryan M.; Brewer, James; Vanderswag, Helen; Fleisher, Adam; Heidebrink, Judith L.; Lord, Joanne L.; Mason, Sara S.; Albers, Colleen S.; Knopman, David; Johnson, Kris; Doody, Rachelle S.; Villanueva-Meyer, Javier; Chowdhury, Munir; Rountree, Susan; Dang, Mimi; Stern, Yaakov; Honig, Lawrence S.; Bell, Karen L.; Ances, Beau; Morris, John C.; Carroll, Maria; Creech, Mary L.; Franklin, Erin; Mintun, Mark A.; Schneider, Stacy; Oliver, Angela; Marson, Daniel; Griffith, Randall; Clark, David; Geldmacher, David; Brockington, John; Roberson, Erik; Natelson Love, Marissa; Grossman, Hillel; Mitsis, Effie; Shah, Raj C.; deToledo-Morrell, Leyla; Duara, Ranjan; Varon, Daniel; Greig, Maria T.; Roberts, Peggy; Albert, Marilyn; Onyike, Chiadi; D’Agostino, Daniel; Kielb, Stephanie; Galvin, James E.; Cerbone, Brittany; Michel, Christina A.; Pogorelec, Dana M.; Rusinek, Henry; de Leon, Mony J.; Glodzik, Lidia; De Santi, Susan; Doraiswamy, P. Murali; Petrella, Jeffrey R.; Borges-Neto, Salvador; Wong, Terence Z.; Coleman, Edward; Smith, Charles D.; Jicha, Greg; Hardy, Peter; Sinha, Partha; Oates, Elizabeth; Conrad, Gary; Porsteinsson, Anton P.; Goldstein, Bonnie S.; Martin, Kim; Makino, Kelly M.; Ismail, M. Saleem; Brand, Connie; Mulnard, Ruth A.; Thai, Gaby; Mc-Adams-Ortiz, Catherine; Womack, Kyle; Mathews, Dana; Quiceno, Mary; Levey, Allan I.; Lah, James J.; Cellar, Janet S.; Burns, Jeffrey M.; Swerdlow, Russell H.; Brooks, William M.; Apostolova, Liana; Tingus, Kathleen; Woo, Ellen; Silverman, Daniel H.S.; Lu, Po H.; Bartzokis, George; Graff-Radford, Neill R.; Parfitt, Francine; Kendall, Tracy; Johnson, Heather; Farlow, Martin R.; Hake, Ann Marie; Matthews, Brandy R.; Brosch, Jared R.; Herring, Scott; Hunt, Cynthia; van Dyck, Christopher H.; Carson, Richard E.; MacAvoy, Martha G.; Varma, Pradeep; Chertkow, Howard; Bergman, Howard; Hosein, Chris; Black, Sandra; Stefanovic, Bojana; Caldwell, Curtis; Robin Hsiung, Ging-Yuek; Feldman, Howard; Mudge, Benita; Assaly, Michele; Finger, Elizabeth; Pasternack, Stephen; Rachisky, Irina; Trost, Dick; Kertesz, Andrew; Bernick, Charles; Munic, Donna; Mesulam, Marek-Marsel; Lipowski, Kristine; Weintraub, Sandra; Bonakdarpour, Borna; Kerwin, Diana; Wu, Chuang-Kuo; Johnson, Nancy; Sadowsky, Carl; Villena, Teresa; Scott Turner, Raymond; Johnson, Kathleen; Reynolds, Brigid; Sperling, Reisa A.; Johnson, Keith A.; Marshall, Gad; Yesavage, Jerome; Taylor, Joy L.; Lane, Barton; Rosen, Allyson; Tinklenberg, Jared; Sabbagh, Marwan N.; Belden, Christine M.; Jacobson, Sandra A.; Sirrel, Sherye A.; Kowall, Neil; Killiany, Ronald; Budson, Andrew E.; Norbash, Alexander; Lynn Johnson, Patricia; Obisesan, Thomas O.; Wolday, Saba; Allard, Joanne; Lerner, Alan; Ogrocki, Paula; Tatsuoka, Curtis; Fatica, Parianne; Fletcher, Evan; Maillard, Pauline; Olichney, John; DeCarli, Charles; Carmichael, Owen; Kittur, Smita; Borrie, Michael; Lee, T-Y; Bartha, Rob; Johnson, Sterling; Asthana, Sanjay; Carlsson, Cynthia M.; Potkin, Steven G.; Preda, Adrian; Nguyen, Dana; Tariot, Pierre; Burke, Anna; Trncic, Nadira; Reeder, Stephanie; Bates, Vernice; Capote, Horacio; Rainka, Michelle; Scharre, Douglas W; Kataki, Maria; Adeli, Anahita; Zimmerman, Earl A.; Celmins, Dzintra; Brown, Alice D.; Pearlson, Godfrey D.; Blank, Karen; Anderson, Karen; Flashman, Laura A.; Seltzer, Marc; Hynes, Mary L.; Santulli, Robert B.; Sink, Kaycee M.; Gordineer, Leslie; Williamson, Jeff D.; Garg, Pradeep; Watkins, Franklin; Ott, Brian R.; Querfurth, Henry; Tremont, Geoffrey; Salloway, Stephen; Malloy, Paul; Correia, Stephen; Rosen, Howard J.; Miller, Bruce L.; Perry, David; Mintzer, Jacobo; Spicer, Kenneth; Bachman, David; Pomara, Nunzio; Hernando, Raymundo; Sarrael, Antero; Relkin, Norman; Chaing, Gloria; Lin, Michael; Ravdin, Lisa; Smith, Amanda; Ashok Raj, Balebail; Fargher, Kristin (Nature Publishing Group, 2016)
      Phosphatidylinositolbinding clathrin assembly protein (PICALM) gene is one novel genetic player associated with late-onset Alzheimer’s disease (LOAD), based on recent genome wide association studies (GWAS). However, how ...

    • Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair 

      Reynolds, John J.; Walker, Alexandra K.; Gilmore, Edward C.; Walsh, Christopher A.; Caldecott, Keith W. (Oxford University Press, 2012)
      Microcephaly with early-onset, intractable seizures and developmental delay (MCSZ) is a hereditary disease caused by mutations in polynucleotide kinase/phosphatase (PNKP), a DNA strand break repair protein with DNA 5′-kinase ...

    • The Impact of Pooling on Throughput Time in Discretionary Work Settings: An Empirical Investigation of Emergency Department Length of Stay 

      Song, Hummy; Tucker, Anita Lynn; Murrell, Karen L. (2013-05-22)
      We conduct an empirical investigation on the impact of pooling tasks and resources on throughput times in a discretionary work setting. We use an Emergency Department’s (ED) patient-level data (N = 234,334) from 2007 to ...

    • The impact of power generation emissions on ambient PM2.5 pollution and human health in China and India 

      Gao, Meng; Beig, Gufran; Song, Shaojie; Zhang, Hongliang; Hu, Jianlin; Ying, Qi; Liang, Fengchao; Liu, Yang; Wang, Haikun; Lu, Xiao; Zhu, Tong; Carmichael, Gregory R.; Nielsen, Chris; McElroy, Michael (Elsevier BV, 2018-12)
      Emissions from power plants in China and India contain a myriad of fine particulate matter (PM2.5, PM≤2.5 micrometers in diameter) precursors, posing significant health risks among large, densely settled populations. Studies ...

    • Impact of Pre-adapted HIV Transmission 

      Carlson, Jonathan M.; Du, Victor Y.; Pfeifer, Nico; Bansal, Anju; Tan, Vincent Y.F.; Power, Karen; Brumme, Chanson J.; Kreimer, Anat; DeZiel, Charles E.; Fusi, Nicolo; Schaefer, Malinda; Brockman, Mark A.; Gilmour, Jill; Price, Matt A.; Kilembe, William; Haubrich, Richard; John, Mina; Mallal, Simon; Shapiro, Roger; Frater, John; Harrigan, P. Richard; Ndung’u, Thumbi; Allen, Susan; Heckerman, David; Sidney, John; Allen, Todd M.; Goulder, Philip J.R.; Brumme, Zabrina L.; Hunter, Eric; Goepfert, Paul A. (2016)
      Human Leukocyte Antigen class I (HLA) restricted CD8+ T lymphocyte (CTL) responses are critical to HIV-1 control. Although HIV can evade these responses, the longer-term impact of viral escape mutants remains unclear, since ...

    • Impact of prenatal methylmercury exposure on neurobehavioral function at age 14 years 

      Debes, Frodi; Budtz-Jørgensen, Esben; Weihe, Pal; White, Roberta F; Grandjean, Philippe (Elsevier BV, 2006)
      A cohort of 1022 consecutive singleton births was generated during 1987–1988 in the Faroe Islands, where increased methylmercury exposure occurs from traditional seafood diets that include pilot whale meat. The prenatal ...

    • The Impact of Preprinted Prescription Forms on Medication Prescribing Errors in an Ophthalmology Clinic in Northeast Thailand: A Non-Randomised Interventional Study 

      Sanguansak, Thuss; Yospaiboon, Yosanan; Morley, Michael Gerard; Lorch, Alice Carlyle; Hedt, Bethany; Morley, Katharine Elise (BMJ Group, 2012)
      Objectives: To understand the incidence and types of medication prescribing errors in a low resource setting ophthalmology clinic and to determine the impact of a preprinted prescription based on the hospital formulary ...

    • The Impact of Prescribing Safety Alerts for Elderly Persons in an Electronic Medical Record 

      Smith, David H.; Perrin, Nancy; Feldstein, Adrianne; Yang, Xiuhai; Kuang, Daniel; Simon, Steven R.; Sittig, Dean F.; Platt, Richard; Soumerai, Stephen Bertram (American Medical Association (AMA), 2006)
      Background Considerable effort and attention have focused on medication safety in elderly persons; one approach that has been understudied in the outpatient environment is the use of computerized provider order entry with ...

    • The impact of private provision of public education: Empirical evidence from Bogota's concession schools 

      Barrera-Osorio, Felipe (2006)
      In 1999, the city of Bogotá, Colombia launched the Concession School program designed to broaden the coverage and quality of basic education. It consists of a contract between a group of private schools and the public ...

    • The impact of Production Tax Credits on the profitable production of electricity from wind in the U.S. 

      Lu, Xi; Tchou, Jeremy; McElroy, Michael Brendon; Nielsen, Chris (Elsevier BV, 2011)
      A spatial financial model using wind data derived from assimilated meteorological condition was developed to investigate the profitability and competitiveness of onshore wind power in the contiguous U.S. It considers not ...

    • Impact of Public Health Emergencies on Modern Disaster Taxonomy, Planning, and Response 

      Burkle, Frederick; Greenough, P. Gregg (Cambridge University Press (CUP), 2008)
      Current disaster taxonomy describes diversity, distinguishing characteristics, and common relations in disaster event classifications. The impact of compromised public health infrastructure and systems on health consequences ...

    • The Impact of Radiocarbon Dating on Old World Archaeology: Past Achievements and Future Expectations 

      Bar-Yosef, Ofer (University of Arizona, 2000)

    • The Impact of Realistic Age Structure in Simple Models of Tuberculosis Transmission 

      Brooks-Pollock, Ellen; Cohen, Ted; Murray, Megan Blanche (Public Library of Science, 2010)
      Background: Mathematical models of tuberculosis (TB) transmission have been used to characterize disease dynamics, investigate the potential effects of public health interventions, and prioritize control measures. While ...

    • Impact of Reduced Tobacco Smoking on Lung Cancer Mortality in the United States During 1975–2000 

      Moolgavkar, Suresh H.; Holford, Theodore R.; Levy, David T.; Foy, Millenia; Clarke, Lauren; Jeon, Jihyoun; Hazelton, William D.; Meza, Rafael; Schultz, Frank; McCarthy, William; Boer, Robert; Gorlova, Olga; Kimmel, Marek; de Koning, Harry J.; Feuer, Eric J.; Kong, Chung Yin; Gazelle, Guy Scott; McMahon, Pamela Markell (Oxford University Press, 2012)
      Background: Considerable effort has been expended on tobacco control strategies in the United States since the mid-1950s. However, we have little quantitative information on how changes in smoking behaviors have impacted ...

    • The Impact of Regulation on Mortgage Risk: Evidence from India 

      Campbell, John Y.; Ramadorai, Tarun; Ranish, Benjamin (American Economic Association, 2015)
      We employ loan-level data on over a million loans disbursed in India between 1995 and 2010 to understand how fast-changing regulation impacted mortgage lending and risk. Our paper uses changes in regulatory treatment ...

    • The Impact of Reporting a Prior Penicillin Allergy on the Treatment of Methicillin-Sensitive Staphylococcus aureus Bacteremia 

      Blumenthal, Kimberly G.; Shenoy, Erica S.; Huang, Mingshu; Kuhlen, James L.; Ware, Winston A.; Parker, Robert A.; Walensky, Rochelle P. (Public Library of Science, 2016)
      Background: Methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia is a morbid infection with mortality benefit from receipt of parenteral β-lactam therapy. A substantial portion of MSSA bacteremia patients report ...