Browsing by Title
Now showing items 24946-24965 of 55420
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Improving the Statistical Detection of Regulated Genes from Microarray Data Using Intensity-Based Variance Estimation
(BioMed Central, 2004)Background: Gene microarray technology provides the ability to study the regulation of thousands of genes simultaneously, but its potential is limited without an estimate of the statistical significance of the observed ... -
Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements
(Springer Science and Business Media LLC, 2020-11-30)Poor trans-ancestry portability of polygenic risk scores is a consequence of Eurocentric genetic studies and limited knowledge of shared causal variants. Leveraging regulatory annotations may improve portability by ... -
Improving Transfer Pathways: the Impact of Statewide Articulation Policies
(2017-05-08)Students who first enroll in a community college may experience barriers to attain a bachelor’s degree if they lose credits in the process of transferring to a four-year institution. Statewide articulation policies establish ... -
Improving transgender health by building safe clinical environments that promote existing resilience: Results from a qualitative analysis of providers
(BioMed Central, 2015)Background: Transgender (TG) individuals experience discordance between their sex at birth and their gender identity. To better understand the health care needs and characteristics of TG youth that contribute to resilience, ... -
Improving Treatment Intensification to Reduce Cardiovascular Disease Risk: A Cluster Randomized Trial
(BioMed Central, 2012)Background: Blood pressure, lipid, and glycemic control are essential for reducing cardiovascular disease (CVD) risk. Many health care systems have successfully shifted aspects of chronic disease management, including ... -
Improving Women's Health through Universal Health Coverage
(Public Library of Science, 2014)Jonathan Quick and colleagues discuss how women's health world-wide can be improved through universal health coverage. Please see later in the article for the Editors' Summary -
Improving Zinc Finger Nucleases - Strategies for Increasing Gene Editing Activities and Evaluating Off-Target Effects
(2012-08-23)Zinc finger nucleases (ZFNs) induce double-strand DNA breaks at specific recognition sites. ZFNs can dramatically increase the efficiency of incorporating desired insertions, deletions, or substitutions in living cells. ... -
Improvisation in evolution of genes and genomes: whose structure is it anyway?
(Elsevier BV, 2008)Significant progress has been made in recent years in a variety of seemingly unrelated fields such as sequencing, protein structure prediction, and high-throughput transcriptomics and metabolomics. At the same time new ... -
Impulsive Social Influence Increases Impulsive Choices on a Temporal Discounting Task in Young Adults
(Public Library of Science, 2014)Adolescents and young adults who affiliate with friends who engage in impulsive behavior are more likely to engage in impulsive behaviors themselves, and those who associate with prosocial (i.e. more prudent, future oriented) ... -
Impure Dissent: Hip Hop and the Political Ethics of Marginalized Black Urban Youth
(University of Chicago Press, 2015) -
Impurity Induced Spin Texture in Quantum Critical 2D Antiferromagnets
(American Physical Society, 2007) -
Impurity of Stem Cell Graft by Murine Embryonic Fibroblasts – Implications for Cell-Based Therapy of the Central Nervous System
(Frontiers Media S.A., 2014)Stem cells have been demonstrated to possess a therapeutic potential in experimental models of various central nervous system disorders, including stroke. The types of implanted cells appear to play a crucial role. Previously, ... -
Impurity Physics in Resonant X-Ray Scattering and Ultracold Atomic Gases
(2014-10-21)This thesis presents work on theoretical tools used to study transient and quantum-fluctuating impurity potentials that arise in resonant x-ray scattering and ultracold atomic gases. These tools fall under two main classes, ... -
Impurity spin textures across conventional and deconfined quantum critical points of two-dimensional antiferromagnets
(American Physical Society, 2007)We describe the spin distribution in the vicinity of a nonmagnetic impurity in a two-dimensional antiferromagnet undergoing a transition from a magnetically ordered Neel state to a paramagnet with a spin gap. The quantum ... -
Imputation and multiple imputation
(2009) -
Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens
(Public Library of Science, 2013)DNA sequence variation within human leukocyte antigen (HLA) genes mediate susceptibility to a wide range of human diseases. The complex genetic structure of the major histocompatibility complex (MHC) makes it difficult, ... -
Imputing gene expression from optimally reduced probe sets
(2012)Measuring complete gene expression profiles for a large number of experiments is costly. We propose an approach in which a small subset of probes is selected based on a preliminary set of full expression profiles. In ... -
In a Quite Practical Way: The Political Origins of Social Security Unemployment Insurance Policy
(2018-05-10)In the winter of 1930, Franklin Roosevelt requested that six of his fellow governors join him in Albany to discuss the relief and prevention of unemployment across the region. Governor Roosevelt stressed in his invitation, ... -
In Acute Stroke, Can CT Perfusion-Derived Cerebral Blood Volume Maps Substitute for Diffusion-Weighted Imaging in Identifying the Ischemic Core?
(Public Library of Science, 2015)Background and Purpose In the treatment of patients with suspected acute ischemic stroke, increasing evidence suggests the importance of measuring the volume of the irreversibly injured “ischemic core.” The gold standard ... -
In an octopus' garden: a story from Lesbos
(Harvard University, Center for Hellenic Studies, 2015-12-12)In Plutarch’s Banquet of the Seven Sages, the author imagines a remote time when conversations took placein the city of Corinth at a dinner party hosted by the tyrant of that city, Periandros, a historical figure whoselifetime ...