Now showing items 42531-42550 of 56451

    • RECQL5 Suppresses Oncogenic JAK2-Induced Replication Stress and Genomic Instability 

      Chen, Edwin; Ahn, Jong Sook; Sykes, David Brian; Breyfogle, Lawrence J.; Godfrey, Anna L.; Nangalia, Jyoti; Ko, Amy; DeAngelo, Daniel J.; Green, Alexander Robert; Mullally, Ann (Elsevier BV, 2015)
      JAK2V617F is the most common oncogenic lesion in patients with myeloproliferative neoplasms (MPNs). Despite the ability of JAK2V617F to instigate DNA damage in vitro, MPNs are nevertheless characterized by genomic stability. ...
    • Recreating Herschel's Actinometry: An Essay in the Historiography of Experimental Practice 

      Voskuhl, Adelheid Clara (Cambridge University Press, 1997)
      Recreating, as part of doing history, can be a way of reflecting what creating is as part of science. Discussions revolving around historical understanding of the scientific enterprise have recently included strong commitments ...
    • Recreating the heart’s helical structure-function relationship with focused rotary jet spinning 

      Chang, Huibin; Liu, Qihan; Zimmerman, John F.; Lee, Keel Yong; Jin, Qianru; Peters, Michael M.; Rosnach, Michael; Choi, Suji; Kim, Sean L.; Ardoña, Herdeline Ann M.; MacQueen, Luke A.; Chantre, Christophe O.; Motta, Sarah E.; Cordoves, Elizabeth M.; Parker, Kevin (American Association for the Advancement of Science (AAAS), 2022-07-08)
      <jats:p>Helical alignments within the heart’s musculature have been speculated to be important in achieving physiological pumping efficiencies. Testing this possibility is difficult, however, because it is challenging to ...
    • Recruited macrophages elicit atrial fibrillation 

      Hulsmans, Maarten; Schloss, Maximilian J.; Lee, I-Hsiu; Bapat, Aneesh; Iwamoto, Yoshiko; Vinegoni, Claudio; Paccalet, Alexandre; Yamazoe, Masahiro; Grune, Jana; Pabel, Steffen; Momin, Noor; Seung, Hana; Kumowski, Nina; Pulous, Fadi; Keller, Daniel; Bening, Constanze; Green, Ursula; Lennerz, Jochen K.; Mitchell, Richard N.; Lewis, Andrew; Casadei, Barbara; Iborra-Egea, Oriol; Bayes-Genis, Antoni; Sossalla, Samuel; Ong, Chin Siang; Pierson, Richard N.; Aster, Jon C.; Rohde, David; Wojtkiewicz, Gregory R.; Weissleder, Ralph; Swirski, Filip K.; Tellides, George; Tolis, George; Melnitchouk, Serguei; Milan, David J.; Ellinor, Patrick T.; Naxerova, Kamila; Nahrendorf, Matthias
      Atrial fibrillation disrupts contraction of the atria, leading to stroke and heart failure. We here decipher how immune and stromal cells contribute to atrial fibrillation. Single-cell transcriptomes from human atria ...
    • Recruiting a Microtubule-Binding Complex to DNA Directs Chromosome Segregation in Budding Yeast 

      Lacefield, Soni; Lau, Tsz Cham Derek; Murray, Andrew W. (Natur Publishing Group, 2009)
      Accurate chromosome segregation depends on the kinetochore, the complex of proteins that link microtubules to centromeric DNA1. The budding yeast kinetochore consists of more than 80 proteins assembled on a 125bp region ...
    • Recruiting and Hiring Teachers in Six Successful, High-Poverty, Urban Schools 

      Simon, Nicole S. (2015-05-15)
      Good teaching matters, especially for students growing up in poverty. But, effective teaching does not alone depend on the contributions of talented and skilled individuals. Rather, promising pedagogues are far more ...
    • Recruiting and Preparing Quality Teachers 

      Mancenido, Zid (2022-05-10)
      In Paper #1, I investigate the career exploration processes of 96 recent graduates of elite higher education institutions with varying levels of interest and commitment to teaching. My aim is to understand how intrinsic ...
    • Recruiting Small Manufacturing Worksites That Employ Multiethnic, Low-Wage Workforces Into a Cancer Prevention Research Trial 

      Barbeau, Elizabeth M.; Wallace, Lorraine; Lederman, Ruth; Lightman, Nancy; Stoddard, Anne; Sorensen, Glorian (Centers for Disease Control and Prevention, 2004)
      Introduction: Worksites, including those that employ multiethnic, low-wage workforces, represent a strategic venue for reaching populations at risk for developing cancer. Methods: We surveyed 197 small manufacturing worksites ...
    • Recruiting Women Smokers: The Engineering of Consent 

      Brandt, Allan M. (American Medical Women's Association, 1996)
      A range of social forces contributed to the effective recruitment of women to cigarette smoking in the crucial period between 1900 and 1940. Cigarette advertisers and public relations experts recognized the significance ...
    • Recruitment and Retention for Community-Based eHealth Interventions with Populations of Low Socioeconomic Position: Strategies and Challenges 

      Nagler, Rebekah H.; Ramanadhan, Shoba; Minsky, Sara J; Viswanath, Kasisomayajula (Oxford University Press (OUP), 2013)
    • Recruitment and retention of participants in a pragmatic randomized intervention trial at three community health clinics: Results and lessons learned 

      Warner, Erica; Glasgow, Russell E; Emmons, Karen Maria; Bennett, Gary G; Askew, Sandy; Rosner, Bernard Alfred; Colditz, Graham A. (BioMed Central, 2013)
      Background: Obesity and hypertension and their associated health complications disproportionately affect communities of color and people of lower socioeconomic status. Recruitment and retention of these populations in ...
    • Recruitment of faster motor units is associated with greater rates of fascicle strain and rapid changes in muscle force during locomotion 

      Lee, S. S. M.; de Boef Miara, M.; Arnold, A. S.; Biewener, Andrew Austin; Wakeling, J. M. (The Company of Biologists, 2013)
      Animals modulate the power output needed for different locomotor tasks through changes in muscle force production and fascicle strain rate. To generate sufficient force, appropriate motor unit recruitment must occur. ...
    • Recruitment of Scribble to the Synaptic Scaffolding Complex Requires GUK-holder, a Novel DLG Binding Protein 

      Mathew, Dennis; Gramates, L. Sian; Packard, Mary; Thomas, Ulrich; Bilder, David; Perrimon, Norbert; Gorczyca, Michael; Budnik, Vivian (Elsevier BV, 2002-04-02)
      Background Membrane-associated guanylate kinases (MAGUKs), such as Discs-Large (DLG), play critical roles in synapse maturation by regulating the assembly of synaptic multiprotein complexes. Previous studies have revealed ...
    • Recruitment to Multicentre Trials—Lessons from UKCTOCS: Descriptive Study 

      Menon, Usha; Gentry-Maharaj, Aleksandra; Ryan, Andy; Sharma, Aarti; Burnell, Matthew; Hallett, Rachel; Lopez, Alberto; Godfrey, Keith; Oram, David; Herod, Jonathan; Williamson, Karin; Seif, Mourad; Scott, Ian; Mould, Tim; Woolas, Robert; Murdoch, John; Dobbs, Stephen; Amso, Nazar; Leeson, Simon; Cruickshank, Derek; McGuire, Ali; Campbell, Stuart; Fallowfield, Lesley; Parmar, Mahesh; Jacobs, Ian; Lewis, Sarah Catherine; Skates, Steven J. (BMJ Publishing Group, 2008)
      Objective: To describe the factors that contributed to successful recruitment of more than 200,000 women to the UK Collaborative Trial of Ovarian Cancer Screening, one of the largest ever randomised controlled trials. ...
    • Rectal 1% Tenofovir Gel Use Associates with Altered Epidermal Protein Expression 

      Romas, Laura; Birse, Kenzie; Mayer, Kenneth H.; Abou, Max; Westmacott, Garrett; Giguere, Rebecca; Febo, Irma; Cranston, Ross D.; Carballo-Diéguez, Alex; McGowan, Ian; Burgener, Adam (Mary Ann Liebert, Inc., 2016)
      Abstract Rectal use of a 1% tenofovir (TFV) gel is currently being evaluated for HIV prevention. While careful assessment of mucosal safety of candidate microbicides is a primary concern, tools to assess mucosal toxicity ...
    • Rectal mucosal dysplasia in Crohn's disease. 

      Korelitz, B I; Lauwers, Gregory Y.; Sommers, S C (BMJ, 1990)
      Serial sections of 812 rectal biopsy specimens from 356 Crohn's disease patients were analysed for mucosal epithelial dysplasia. Dysplasia was found in 18 patients (5%), with four showing dysplasia on repeat biopsy specimen. ...
    • The Rectal Tonsil: A Reactive Lymphoid Proliferation That May Mimic Lymphoma 

      Farris, Alton B.; Lauwers, Gregory Y.; Ferry, Judith Ann; Zukerberg, Lawrence R. (Ovid Technologies (Wolters Kluwer Health), 2008)
      The rectal tonsil (RT), a localized reactive proliferation of lymphoid tissue occurring in the rectum, can cause diagnostic difficulty; and awareness of this entity can prevent a misdiagnosis of lymphoma. A clinicopathologic ...
    • “Recte Perficitur”: Sermons to the Jews and the Rhetoric of Conversion (1572-1585) 

      De La Guardia, Jennifer Noelle (2022-05-13)
      This dissertation examines the rhetoric of Jewish conversion during the institutionalization of the Roman Catholic practice of preaching to the Jews under Pope Gregory XIII (1572-1585). Focusing primarily on the sermon ...
    • Rectification and Precession-Period Signals in the Climate System 

      Huybers, Peter John; Wunsch, Carl (American Geophysical Union, 2003)
      Precession of the equinoxes has no effect on the mean annual insolation, but does modulate the amplitude of the seasonal cycle. In a linear climate system, there would be no energy near the 21,000 year precession period. ...
    • Rectification in Tunneling Junctions: 2,2′-Bipyridyl-Terminated n -Alkanethiolates 

      Yoon, Hyo Jae; Liao, Kung-ching; Lockett, Matthew R.; Kwok, Sen Wai; Baghbanzadeh, Mostafa; Whitesides, George McClelland (American Chemical Society (ACS), 2014)
      Molecular rectification is a particularly attractive phenomenon to examine in studying structure–property relationships in charge transport across molecular junctions, since the tunneling currents across the same molecular ...