Now showing items 44840-44859 of 56883

    • The role of interpretive studies in medieval Latin philology 

      Ziolkowski, Jan M. (Brepols Publishers NV, 2008)
      Interpretation and philology have a long, rich, and complicated relationship. In one sense philology takes interpretation as its point of departure, while in another philology aims ultimately at facilitating or achieving ...
    • The Role of Interstitials and Surface Defects on Oxidation and Reduction Reactions on Titania 

      Jensen, Stephen C (2013-07-25)
      This thesis focuses on understanding the influence of defect sites in titanium dioxide that drive many types of thermal and photochemical reactions. Two of the most common defects in vacuum are titanium interstitials and ...
    • The Role of Intradiscal Steroids in the Treatment of Discogenic Low Back Pain 

      Muzin, Stefan C.; Isaac, Zacharia; Walker, Joseph (Springer Verlag, 2007)
      LBP is one of the most common reasons for visiting a doctor and is the most common cause of disability under age 45. Amongst a variety of etiologies, internal disc disruption (IDD) has been postulated as an important cause ...
    • The role of intrinsic muscle mechanics in the neuromuscular control of stable running in the guinea fowl 

      Daley, M. A.; Voloshina, A.; Biewener, Andrew Austin (Wiley-Blackwell, 2009)
      Here we investigate the interplay between intrinsic mechanical and neural factors in muscle contractile performance during running, which has been less studied than during walking. We report in vivo recordings of the ...
    • Role of invariant natural killer T cell subsets in adipose tissue homeostasis 

      LaMarche, Nelson Martin (2020-09-25)
      Obesity and its related metabolic disorders have the potential to reduce the human life span by 5-20 years, being key drivers of deadly maladies such as cancer, diabetes, and cardiovascular disease. At the heart of these ...
    • Role of Kappa-Opioid Receptors in Stress-Induced Behaviors 

      Van't Veer, Ashlee Victoria (2013-10-08)
      The development of anxiety and mood disorders often coincides with exposure to stress. Accumulating evidence indicates that both corticotropin-releasing factor (CRF) and dynorphin, the endogenous ligand for the kappa-opioid ...
    • The role of ketamine in addressing the anesthesia gap in low-resource settings 

      Suarez, Sebastian; Burke, Thomas; Yusufali, Taha; Makin, Jennifer; Sessler, Daniel I. (Elsevier BV, 2018-09)
    • The Role of Kinds in the Semantics of Ceteris Paribus Laws 

      Nickel, Bernhard (Springer Science + Business Media, 2014)
      This paper investigates the interaction between semantic theories for cp-laws (roughly, laws that hold “all things equal”) and metaphysical theories of kinds in the special sciences. Its central conclusion is that cp-laws ...
    • Role of KIR3DS1 in Human Diseases 

      Körner, Christian; Altfeld, Marcus (Frontiers Media S.A., 2012)
      The function of natural killer (NK) cells is controlled by several activating and inhibitory receptors, including the family of killer-immunoglobulin-like receptors (KIRs). One distinctive feature of KIRs is the extensive ...
    • The Role of KRAS rs61764370 in Invasive Epithelial Ovarian Cancer: Implications for Clinical Testing 

      Pharoah, P. D. P.; Palmieri, R. T.; Ramus, S. J.; Gayther, S. A.; Andrulis, I. L.; Anton-Culver, H.; Antonenkova, N.; Antoniou, A. C.; Goldgar, D.; Beattie, M. S.; Beckmann, M. W.; Birrer, Michael James; Bogdanova, N.; Bolton, K. L.; Brewster, W.; Brooks-Wilson, A.; Brown, R.; Butzow, R.; Caldes, T.; Caligo, M. A.; Campbell, I.; Chang-Claude, J.; Chen, Y. A.; Cook, L. S.; Couch, F. J.; Cramer, Daniel William; Cunningham, J. M.; Despierre, E.; Doherty, J. A.; Dork, T.; Durst, M.; Eccles, D. M.; Ekici, A. B.; Easton, D.; Fasching, P. A.; de Fazio, A.; Fenstermacher, D. A.; Flanagan, J. M.; Fridley, B. L.; Friedman, E.; Gao, B.; Sinilnikova, O.; Gentry-Maharaj, A.; Godwin, A. K.; Goode, E. L.; Goodman, M. T.; Gross, J.; Hansen, T. V. O.; Harnett, P.; Rookus, M.; Heikkinen, T.; Hein, R.; Hogdall, C.; Hogdall, E.; Iversen, E. S.; Jakubowska, A.; Johnatty, S. E.; Karlan, B. Y.; Kauff, N. D.; Kaye, S. B.; Chenevix-Trench, G.; Kelemen, L. E.; Kiemeney, L. A.; Kjaer, S. K.; Lambrechts, D.; LaPolla, J. P.; Lazaro, C.; Le, N. D.; Leminen, A.; Leunen, K.; Levine, D. A.; Lu, Y.; Lundvall, L.; Macgregor, S.; Marees, T.; Massuger, L. F.; McLaughlin, J. R.; Menon, U.; Montagna, M.; Moysich, K. B.; Narod, S. A.; Nathanson, K. L.; Nedergaard, L.; Ness, R. B.; Nevanlinna, H.; Nickels, S.; Osorio, A.; Paul, J.; Pearce, C. L.; Phelan, C. M.; Pike, M. C.; Radice, P.; Rossing, M. A.; Schildkraut, J. M.; Sellers, T. A.; Singer, C. F.; Song, H.; Stram, D. O.; Sutphen, R.; Lindblom, A.; Terry, Kathryn Lynne; Tsai, Y.-Y.; van Altena, A. M.; Vergote, I.; Vierkant, R. A.; Vitonis, A. F.; Walsh, C.; Wang-Gohrke, S.; Wappenschmidt, B.; Wu, A. H.; Ziogas, A.; Berchuck, A.; Risch, H. A. (American Association for Cancer Research (AACR), 2011)
      Purpose An assay for the single nucleotide polymorphism (SNP) rs61764370 has recently been commercially marketed as a clinical test to aid ovarian cancer risk evaluation in women with family histories of the disease. ...
    • The Role of Latin America’s Land and Water Resources for Global Food Security: Environmental Trade-Offs of Future Food Production Pathways 

      Flachsbarth, Insa; Willaarts, Bárbara; Xie, Hua; Pitois, Gauthier; Mueller, Nathaniel D.; Ringler, Claudia; Garrido, Alberto (Public Library of Science, 2015)
      One of humanity’s major challenges of the 21st century will be meeting future food demands on an increasingly resource constrained-planet. Global food production will have to rise by 70 percent between 2000 and 2050 to ...
    • The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy 

      Wang, Leo; Rao, Tirzah; Rowe, Robert Grant; Nguyen, Phi; Sullivan, Jessica J; Pearson, Daniel Stark; Doulatov, Sergei; Wu, Linwei; Lindsley, Robert Coleman; Zhu, Hao; DeAngelo, Daniel J.; Daley, George Quentin; Wagers, Amy Jo (Nature Publishing Group, 2015)
      Mast cells are critical components of the innate immune system and important for host 48 defense, allergy, autoimmunity, tissue regeneration, and tumor progression.Dysregulated 49 mastcell development leads to systemic ...
    • The role of lineage in identity formation among black Americans 

      Waters, Mary C. (Springer Science + Business Media, 1991)
    • Role of lipegfilgrastim in the management of chemotherapy-induced neutropenia 

      Hoggatt, Jonathan; Tate, Tiffany A; Pelus, Louis M (Dove Medical Press, 2015)
      Chemotherapy, irradiation, and other agents are widely used to target the process of cell division in neoplastic cells. However, while these therapies are effective against most cancers, the high proliferative rate of the ...
    • The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults 

      Valenca, Guilherme T.; Srivastava, Gyan P.; Oliveira-Filho, Jamary; White, Charles C.; Yu, Lei; Schneider, Julie A.; Buchman, Aron S.; Shulman, Joshua M.; Bennett, David A.; De Jager, Philip L. (Public Library of Science, 2016)
      Background and Objective Recently, we have shown that the Parkinson’s disease (PD) susceptibility locus MAPT (microtubule associated protein tau) is associated with parkinsonism in older adults without a clinical diagnosis ...
    • The role of maternal-specific H3K9me3 modification in establishing imprinted X-chromosome inactivation and embryogenesis in mice 

      Fukuda, Atsushi; Tomikawa, Junko; Miura, Takumi; Hata, Kenichiro; Nakabayashi, Kazuhiko; Eggan, Kevin; Akutsu, Hidenori; Umezawa, Akihiro (Nature Pub. Group, 2014)
      Maintaining a single active X-chromosome by repressing Xist is crucial for embryonic development in mice. Although the Xist activator RNF12/RLIM is present as a maternal factor, maternal Xist (Xm-Xist) is repressed during ...
    • The Role of Mechanical Forces in Patterning and Morphogenesis of the Vertebrate Gut 

      Shyer, Amy Elizabeth (2013-09-30)
      The vertebrate small intestine is responsible for nutrient absorption during digestion. To this end, the surface area of the gut tube is maximally expanded, both through a series of loops extending its length and via the ...
    • The Role of Mesalamine in the Treatment of Ulcerative Colitis 

      Karagozian, Raffi; Burakoff, Robert (Dove Medical Press, 2007)
      Ulcerative colitis (UC) is a chronic inflammatory condition of unclear etiology affecting the large bowel, most commonly the rectum and extending proximally in a continuous fashion. The overall principle in the pathophysiolgy ...
    • Role of Microbiota in Strengthening Ocular Mucosal Barrier Function Through Secretory IgA 

      Wright, Quentin George (2017-05-05)
      Unlike other mucosal sites, the ocular mucosal surfaces are paucibacterial, which suggests that effective cellular and molecular mechanisms ensure limited commensal presence. Given that secretory IgA (SIgA) is a major ...
    • The Role of Microenvironmental Cues in Cardiomyogenesis and Pathogenesis 

      Horton, Renita Elillian (2014-06-06)
      The cellular microenvironment consists of soluble and insoluble factors that provide signals that dictate cell behavior and cell fate. Limited characterization has hindered our ability to mimic the physiological or ...