Now showing items 5906-5925 of 57128

    • Bumetanide Enhances Phenobarbital Efficacy in a Rat Model of Hypoxic Neonatal Seizures 

      Cleary, Ryan T.; Sun, Hongyun; Huynh, Thanhthao; Manning, Simon; Li, Yijun; Rotenberg, Alexander; Talos, Delia M.; Kahle, Kristopher Thomas; Jackson, Michele; Rakhade, Sanjay N.; Berry, Gerard T.; Jensen, Frances Elizabeth (Public Library of Science, 2013)
      Neonatal seizures can be refractory to conventional anticonvulsants, and this may in part be due to a developmental increase in expression of the neuronal Na+-K+-2 Cl− cotransporter, NKCC1, and consequent paradoxical ...
    • Bunched, the Drosophila Homolog of the Mammalian Tumor Suppressor TSC-22, Promotes Cellular Growth 

      Gluderer, Silvia; Oldham, Sean; Rintelen, Felix; Sulzer, Andrea; Schütt, Corina; Wu, Xiaodong; Raftery, Laurel Anne; Hafen, Ernst; Stocker, Hugo (BioMed Central, 2008)
      Background: Transforming Growth Factor-β1 stimulated clone-22 (TSC-22) is assumed to act as a negative growth regulator and tumor suppressor. TSC-22 belongs to a family of putative transcription factors encoded by four ...
    • Bundled Systems and Better Law: Against the Leflar Method of Resolving Conflicts of Law 

      Neylan, Kevin Michael (2015)
      Suppose Jones is a New Hampshire fireworks dealer. Smith comes up from Massachusetts, buys a cache, and brings it home. One night Smith sets off a Roman Candle in his backyard, but mishandles it and badly injures himself. ...
    • Bundling and Entrenchment 

      Bebchuk, Lucian Arye; Ehud, Kamar (Harvard University, Harvard Law School, 2010)
      Because corporate charters can be amended only with shareholder approval, it is widely believed that new charter provisions appear in midstream only if shareholders favor them. However, the approval requirement may fail ...
    • Bundling and Firm Reputation 

      Dana, James Dwight; Spier, Kathryn E. (John M. Olin Center for Law, Economics, and Business. Harvard Law School., 2009)
      By bundling experience goods, a manufacturer can more easily maintain a reputation for high quality over time. Formally, we extend Klein and Lefler's (1981) repeated moral hazard model of product quality to consider ...
    • Buñuel, Lorca, Dalí: El Enigma Sin Fin (Book Review) 

      Fernandez-cifuentes, Luis (El Colegio de Mexico, A.C., 1989-01-01)
      Un tema de completa vigencia, un premio de prestigio y una amenidad poco frecuente han conseguido para este libro reseñas innumerables y justamente elogiosas. La mayoría, sin embargo, se limita a describirlo como un minucioso ...
    • Buprenorphine Treatment for Opioid Addiction in the Primary Care Setting: Predictors of Treatment Success and Failure 

      Drago, Joshua (2015-06-08)
      Buprenorphine is a partial mu-opioid agonist with well-demonstrated efficacy in the medical treatment of opioid addiction. Little is known about which patients respond successfully to treatment with buprenorphine. To help ...
    • Bupropion Reduces Some of the Symptoms of Marihuana Withdrawal in Chronic Marihuana Users: A Pilot Study 

      Penetar, David Michael; Looby, Alison R.; Ryan, Elizabeth T.; Maywalt, Melissa A.; Lukas, Scott E. (Libertas Academica, 2012)
      Bupropion’s (Zyban® SR) effectiveness to treat symptoms experienced in marihuana withdrawal was tested in a double-blind, placebo-controlled study with chronic, heavy marihuana users. Participants maintained their usual ...
    • Burden and predictors of hypertension in India: results of SEEK (Screening and Early Evaluation of Kidney Disease) study 

      Farag, Youssef MK; Mittal, Bharati V; Keithi-Reddy, Sai Ram; Acharya, Vidya N; Almeida, Alan F; C, Anil; HS, Ballal; P, Gaccione; R, Issacs; Jasuja, Sanjiv; AL, Kirpalani; V, Kher; GK, Modi; Nainan, Georgy; Prakash, Jai; Rajapurkar, Mohan M; DS, Rana; Sreedhara, Rajanna; DK, Sinha; Shah, Bharat V; Sunder, Sham; Sharma, Raj Kumar; Seetharam, Sridevi; Raju, Tatapudi Ravi; Singh, Ajay K (BioMed Central, 2014)
      Background: Hypertension (HTN) is one of the major causes of cardiovascular morbidity and mortality. The objective of the study was to investigate the burden and predictors of HTN in India. Methods: 6120 subjects participated ...
    • Burden and Rates of Treatment and Control of Cardiovascular Disease Risk Factors in Obesity 

      Molenaar, Esther A.; Hwang, Shih-Jen; Vasan, Ramachandran S.; Grobbee, Diederick E.; Meigs, James Benjamin; D'Agostino, Ralph B.; Levy, Daniel; Fox, Caroline (American Diabetes Association, 2008)
      OBJECTIVE—Obesity is associated with an increased risk for cardiovascular disease (CVD). We sought to determine rates of treatment and control of CVD risk factors among normal weight, overweight, and obese individuals in ...
    • Burden of antimicrobial resistance: compared to what? 

      de Kraker, Marlieke E. A.; Lipsitch, Marc (2020)
      Background There has been an increased focus on the public health burden of antimicrobial resistance (AMR). This raises conceptual challenges such as determining how much harm multi-drug resistant organisms do compared ...
    • Burden of Changes in Pill Appearance for Patients Receiving Generic Cardiovascular Medications After Myocardial Infarction 

      Kesselheim, Aaron Seth; Bykov, Katsiaryna; Avorn, Jerry Lewis; Tong, Angela; Doherty, Michael Joseph; Choudhry, Niteesh Kumar (American College of Physicians, 2014)
      Background: Generic prescription drugs made by different manufacturers may vary in color or shape, and switching among these drug products may interrupt medication use. Objective: To determine whether nonpersistent use of ...
    • The burden of chronic mercury intoxication in artisanal small-scale gold mining in Zimbabwe: data availability and preliminary estimates 

      Steckling, Nadine; Bose-O’Reilly, Stephan; Pinheiro, Paulo; Plass, Dietrich; Shoko, Dennis; Drasch, Gustav; Bernaudat, Ludovic; Siebert, Uwe; Hornberg, Claudia (BioMed Central, 2014)
      Background: Artisanal small-scale gold mining (ASGM) is a poverty-driven activity practiced in over 70 countries worldwide. Zimbabwe is amongst the top ten countries using large quantities of mercury to extract gold from ...
    • The burden of clostridium difficile infection: estimates of the incidence of CDI from U.S. Administrative databases 

      Olsen, Margaret A.; Young-Xu, Yinong; Stwalley, Dustin; Kelly, Ciarán P.; Gerding, Dale N.; Saeed, Mohammed J.; Mahé, Cedric; Dubberke, Erik R. (BioMed Central, 2016)
      Background: Many administrative data sources are available to study the epidemiology of infectious diseases, including Clostridium difficile infection (CDI), but few publications have compared CDI event rates across databases ...
    • Burden of disease and costs of exposure to endocrine disrupting chemicals in the European Union: an updated analysis 

      Trasande, L.; Zoeller, R. T.; Hass, U.; Kortenkamp, A.; Grandjean, Philippe; Myers, J. P.; DiGangi, J.; Hunt, P. M.; Rudel, R.; Sathyanarayana, S.; Bellanger, M.; Hauser, R.; Legler, J.; Skakkebaek, N. E.; Heindel, J. J. (Wiley-Blackwell, 2016)
      A previous report documented that endocrine disrupting chemicals contribute substantially to certain forms of disease and disability. In the present analysis, our main objective was to update a range of health and economic ...
    • The Burden of Disease and Injury in the United States 1996 

      Begg, Stephen; Tomijima, Niels; Majmudar, Meghna; Bulzacchelli, Maria T; Ebrahim, Shahul; Gaber Kreiser, Jessica; Hogan, Mollie; Michaud, Catherine M.; McKenna, Matthew; Ezzati, Majid; Salomon, Joshua A.; Murray, Christopher (BioMed Central, 2006)
      Background: Burden of disease studies have been implemented in many countries using the Disability-Adjusted Life Year (DALY) to assess major health problems. Important objectives of the study were to quantify intra-country ...
    • The Burden of Disease and the Changing Task of Medicine 

      Jones, David Shumway; Podolsky, Scott Harris; Greene, Jeremy Alan (New England Journal of Medicine (NEJM/MMS), 2012)
    • The Burden of Guilt: Heavy Backpacks, Light Snacks, and Enhanced Morality 

      Kouchaki, Maryam; Gino, Francesca; Jami, Ata (American Psychological Association, 2013-09-06)
      Drawing on the embodied simulation account of emotional information processing, we argue that the physical experience of weight is associated with the emotional experience of guilt and thus that weight intensifies the ...
    • The burden of hypertension in sub-Saharan Africa: a four-country cross sectional study 

      Guwatudde, David; Nankya-Mutyoba, Joan; Kalyesubula, Robert; Laurence, Carien; Adebamowo, Clement; Ajayi, IkeOluwapo; Bajunirwe, Francis; Njelekela, Marina; Chiwanga, Faraja S.; Reid, Todd; Volmink, Jimmy; Adami, Hans-Olov; Holmes, Michelle D.; Dalal, Shona (BioMed Central, 2015)
      Background: Hypertension, the leading single cause of morbidity and mortality worldwide, is a growing public health problem in sub-Saharan Africa (SSA). Few studies have estimated and compared the burden of hypertension ...
    • Burden of illness score for elderly persons (BISEP): Risk adjustment incorporating the cumulative impact of diseases, physiologic abnormalities and functional impairments. 

      Inouye, Sharon; Bogardus, Sidney T.; Vitagliano, Gail; Desai, Mayur; Williams, Christianna; Grady, Jacqueline; Scinto, Jeanne (Lippincott Williams & Wilkins, Inc., 2003)
      Background/Objectives. To develop and validate a new risk adjustment index-the Burden of Illness Score for Elderly Persons (BISEP)-which integrates multiple domains, including diseases, physiologic abnormalities, and ...