Browsing by FAS Department "Health Sciences and Technology"
Now showing items 1-6 of 6
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Dynamic Expression of Primary Cilia Across Diverse Human Cancers
(2019-06-28)Primary cilia are highly conserved organelles that are best known for their role in signal transduction in development. However, their significance in cancer biology is unclear, with some studies reporting that cilia are ... -
Modulating BLA-vHPC Synapses to Reduce Anxiety-Like Behavior in Mice
(2019-06-28)Although anxiety disorders are some of the most prevalent mental health conditions, current pharmacotherapies are often ineffective or associated with negative side effects because the neural mechanisms underlying anxiety ... -
Mouse Models Expresssing Precursors of Broadly Neutralizing Antibodies Against HIV
(2019-06-28)An effective HIV vaccine would undoubtedly be the best solution for controlling the AIDS pandemic. Unfortunately, none of the numerous HIV-1 vaccine development efforts have succeeded to date. The enormous diversity of ... -
Predictive Value of Ventilatory Efficiency Across Categories of Heart Failure
(2019-06-28)Background: In cardiopulmonary stress testing (CPET), minute ventilation-carbon dioxide production relationship (VE/VCO2 slope) strongly predicts outcomes in heart failure (HF). A VE/VCO2 classification system evaluated ... -
Stem Cell Hierarichies within Tumor Genetic Subclones
(2019-06-28)Intratumoral heterogeneity has been appreciated at the genetic and transcriptional levels, yet it remains unclear how they relate to one another. My thesis project applies a novel qPCR technique to combine single-cell ... -
The Role of GM-CSF in Myocardial Infarction
(2019-06-28)Myocardial infarction (MI) is characterized by an obstruction of blood flow to the myocardium, leading to deprivation of oxygen and eventually, irreversible tissue death. After tissue death, intense inflammation occurs, ...